2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide

C123H129F17N16O6 — CID 158793787

About 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide

2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide (PubChem CID 158793787) has the molecular formula C123H129F17N16O6 and a molecular weight of 2250.46 g/mol. Its IUPAC name is 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide.

Molecular Properties

• Compound Name: 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide
• PubChem CID: 158793787
• Molecular Formula: C123H129F17N16O6
• Molecular Weight: 2250.46 g/mol
• Exact Mass: 2249.00
• IUPAC Name: 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide
• SMILES: CC(C)C(=O)Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1.CC1=C(c2ccc(NC(=O)C(C)C)nc2)CC2CCCC2C1.CC1=C(c2ccc(NC(=O)c3c(F)cccc3F)nc2)CC2CCCC2C1.Cc1ccccc1C(=O)Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1.O=C(Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1)c1c(F)cccc1F.O=C(Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1)c1ccccc1F
• InChI: InChI=1S/C22H22F3N3O.C22H22F2N2O.C21H18F5N3O.C21H19F4N3O.C19H26N2O.C18H22F3N3O/c1-13-5-2-3-8-16(13)21(29)28-20-12-26-19(11-27-20)17-9-14-6-4-7-15(14)10-18(17)22(23,24)25;1-13-10-14-4-2-5-15(14)11-17(13)16-8-9-20(25-12-16)26-22(27)21-18(23)6-3-7-19(21)24;22-15-5-2-6-16(23)19(15)20(30)29-18-10-27-17(9-28-18)13-7-11-3-1-4-12(11)8-14(13)21(24,25)26;22-17-7-2-1-6-14(17)20(29)28-19-11-26-18(10-27-19)15-8-12-4-3-5-13(12)9-16(15)21(23,24)25;1-12(2)19(22)21-18-8-7-16(11-20-18)17-10-15-6-4-5-14(15)9-13(17)3;1-10(2)17(25)24-16-9-22-15(8-23-16)13-6-11-4-3-5-12(11)7-14(13)18(19,20)21/h2-3,5,8,11-12,14-15H,4,6-7,9-10H2,1H3,(H,27,28,29);3,6-9,12,14-15H,2,4-5,10-11H2,1H3,(H,25,26,27);2,5-6,9-12H,1,3-4,7-8H2,(H,28,29,30);1-2,6-7,10-13H,3-5,8-9H2,(H,27,28,29);7-8,11-12,14-15H,4-6,9-10H2,1-3H3,(H,20,21,22);8-12H,3-7H2,1-2H3,(H,23,24,25)
• InChIKey: ISPNCJAERJVZMY-UHFFFAOYSA-N
• XLogP: 31.34
• TPSA: 303.50 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 16
• Rotatable Bonds: 18
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2250.46
LogP ≤ 5	31.34
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	16

Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide?

The IUPAC name of 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide (CID 158793787) is 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide.

What is the SMILES notation for 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide?

The canonical SMILES for 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide is CC(C)C(=O)Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1.CC1=C(c2ccc(NC(=O)C(C)C)nc2)CC2CCCC2C1.CC1=C(c2ccc(NC(=O)c3c(F)cccc3F)nc2)CC2CCCC2C1.Cc1ccccc1C(=O)Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1.O=C(Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1)c1c(F)cccc1F.O=C(Nc1cnc(C2=C(C(F)(F)F)CC3CCCC3C2)cn1)c1ccccc1F.

What is the InChIKey of 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide?

The InChIKey is ISPNCJAERJVZMY-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H22F3N3O.C22H22F2N2O.C21H18F5N3O.C21H19F4N3O.C19H26N2O.C18H22F3N3O/c1-13-5-2-3-8-16(13)21(29)28-20-12-26-19(11-27-20)17-9-14-6-4-7-15(14)10-18(17)22(23,24)25;1-13-10-14-4-2-5-15(14)11-17(13)16-8-9-20(25-12-16)26-22(27)21-18(23)6-3-7-19(21)24;22-15-5-2-6-16(23)19(15)20(30)29-18-10-27-17(9-28-18)13-7-11-3-1-4-12(11)8-14(13)21(24,25)26;22-17-7-2-1-6-14(17)20(29)28-19-11-26-18(10-27-19)15-8-12-4-3-5-13(12)9-16(15)21(23,24)25;1-12(2)19(22)21-18-8-7-16(11-20-18)17-10-15-6-4-5-14(15)9-13(17)3;1-10(2)17(25)24-16-9-22-15(8-23-16)13-6-11-4-3-5-12(11)7-14(13)18(19,20)21/h2-3,5,8,11-12,14-15H,4,6-7,9-10H2,1H3,(H,27,28,29);3,6-9,12,14-15H,2,4-5,10-11H2,1H3,(H,25,26,27);2,5-6,9-12H,1,3-4,7-8H2,(H,28,29,30);1-2,6-7,10-13H,3-5,8-9H2,(H,27,28,29);7-8,11-12,14-15H,4-6,9-10H2,1-3H3,(H,20,21,22);8-12H,3-7H2,1-2H3,(H,23,24,25).

What are the key properties of 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide?

2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide has a molecular weight of 2250.46 g/mol, XLogP of 31.34, 18 rotatable bonds, 6 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for 2,6-difluoro-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]benzamide;2,6-difluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-fluoro-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-(6-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl)-2-pyridinyl]propanamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]benzamide;2-methyl-N-[5-[6-(trifluoromethyl)-2,3,3a,4,7,7a-hexahydro-1H-inden-5-yl]pyrazin-2-yl]propanamide is sourced from PubChem (CID 158793787), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).