N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine

C100H73BrCl2F11N25O6 — CID 158849999

About N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine

N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine (PubChem CID 158849999) has the molecular formula C100H73BrCl2F11N25O6 and a molecular weight of 2080.64 g/mol. Its IUPAC name is N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine.

Molecular Properties

• Compound Name: N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine
• PubChem CID: 158849999
• Molecular Formula: C100H73BrCl2F11N25O6
• Molecular Weight: 2080.64 g/mol
• Exact Mass: 2077.46
• IUPAC Name: N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine
• SMILES: COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(Br)cc4)n3)n2c1.COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(Cl)cc4)n3)n2c1.COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccccc4)n3)n2c1.COc1ccc2nc(C)c(-c3cc(C#N)cc(Nc4ccc(Cl)cc4)n3)n2c1.COc1ccc2nc(C)c(-c3cc(C#N)cc(Nc4ccc(OC(F)F)cc4)n3)n2c1
• InChI: InChI=1S/C22H17F2N5O2.C21H16ClN5O.C19H13BrF3N5O.C19H13ClF3N5O.C19H14F3N5O/c1-13-21(29-12-17(30-2)7-8-20(29)26-13)18-9-14(11-25)10-19(28-18)27-15-3-5-16(6-4-15)31-22(23)24;1-13-21(27-12-17(28-2)7-8-20(27)24-13)18-9-14(11-23)10-19(26-18)25-16-5-3-15(22)4-6-16;2*1-29-13-6-7-16-27-18(19(21,22)23)17(28(16)10-13)14-8-24-9-15(26-14)25-12-4-2-11(20)3-5-12;1-28-13-7-8-16-26-18(19(20,21)22)17(27(16)11-13)14-9-23-10-15(25-14)24-12-5-3-2-4-6-12/h3-10,12,22H,1-2H3,(H,27,28);3-10,12H,1-2H3,(H,25,26);2*2-10H,1H3,(H,25,26);2-11H,1H3,(H,24,25)
• InChIKey: IZICZCUTDXUJCK-UHFFFAOYSA-N
• XLogP: 25.01
• TPSA: 352.73 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 31
• Rotatable Bonds: 22
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2080.64
LogP ≤ 5	25.01
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine?

The IUPAC name of N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine (CID 158849999) is N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine.

What is the SMILES notation for N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine?

The canonical SMILES for N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine is COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(Br)cc4)n3)n2c1.COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccc(Cl)cc4)n3)n2c1.COc1ccc2nc(C(F)(F)F)c(-c3cncc(Nc4ccccc4)n3)n2c1.COc1ccc2nc(C)c(-c3cc(C#N)cc(Nc4ccc(Cl)cc4)n3)n2c1.COc1ccc2nc(C)c(-c3cc(C#N)cc(Nc4ccc(OC(F)F)cc4)n3)n2c1.

What is the InChIKey of N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine?

The InChIKey is IZICZCUTDXUJCK-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H17F2N5O2.C21H16ClN5O.C19H13BrF3N5O.C19H13ClF3N5O.C19H14F3N5O/c1-13-21(29-12-17(30-2)7-8-20(29)26-13)18-9-14(11-25)10-19(28-18)27-15-3-5-16(6-4-15)31-22(23)24;1-13-21(27-12-17(28-2)7-8-20(27)24-13)18-9-14(11-23)10-19(26-18)25-16-5-3-15(22)4-6-16;2*1-29-13-6-7-16-27-18(19(21,22)23)17(28(16)10-13)14-8-24-9-15(26-14)25-12-4-2-11(20)3-5-12;1-28-13-7-8-16-26-18(19(20,21)22)17(27(16)11-13)14-9-23-10-15(25-14)24-12-5-3-2-4-6-12/h3-10,12,22H,1-2H3,(H,27,28);3-10,12H,1-2H3,(H,25,26);2*2-10H,1H3,(H,25,26);2-11H,1H3,(H,24,25).

What are the key properties of N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine?

N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine has a molecular weight of 2080.64 g/mol, XLogP of 25.01, 22 rotatable bonds, 5 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for N-(4-bromophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-(4-chloroanilino)-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-(4-chlorophenyl)-6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(difluoromethoxy)anilino]-6-(6-methoxy-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;6-[6-methoxy-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-phenylpyrazin-2-amine is sourced from PubChem (CID 158849999), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).