3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide

C140H103Cl2F4N25O — CID 158869420

IUPAC3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide
SMILESCc1cc(-c2ncccc2-c2ccc3ncnc(NCCc4cccnc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(NCc4ccncc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(Nc4cccc(C(N)=O)c4)c3c2)ccc1F.Clc1cccc(-c2ncccc2-c2cnc3ncccc3c2)c1.Fc1ccc(-c2ncccc2-c2cnc3ncccc3c2)cc1Cl.Nc1ncnc2ccc(-c3cccnc3-c3cccc(C4CC4)c3)cc12
InChIInChI=1S/C27H20FN5O.C27H22FN5.C26H20FN5.C22H18N4.C19H11ClFN3.C19H12ClN3/c1-16-12-18(7-9-23(16)28)25-21(6-3-11-30-25)17-8-10-24-22(14-17)27(32-15-31-24)33-20-5-2-4-19(13-20)26(29)34;1-18-14-21(6-8-24(18)28)26-22(5-3-12-30-26)20-7-9-25-23(15-20)27(33-17-32-25)31-13-10-19-4-2-11-29-16-19;1-17-13-20(4-6-23(17)27)25-21(3-2-10-29-25)19-5-7-24-22(14-19)26(32-16-31-24)30-15-18-8-11-28-12-9-18;23-22-19-12-16(8-9-20(19)25-13-26-22)18-5-2-10-24-21(18)17-4-1-3-15(11-17)14-6-7-14;20-16-10-12(5-6-17(16)21)18-15(4-2-7-22-18)14-9-13-3-1-8-23-19(13)24-11-14;20-16-6-1-4-13(11-16)18-17(7-3-8-21-18)15-10-14-5-2-9-22-19(14)23-12-15/h2-15H,1H3,(H2,29,34)(H,31,32,33);2-9,11-12,14-17H,10,13H2,1H3,(H,31,32,33);2-14,16H,15H2,1H3,(H,30,31,32);1-5,8-14H,6-7H2,(H2,23,25,26);1-11H;1-12H
InChIKeyJBQPLKDPLTVTGF-UHFFFAOYSA-N
MW2298.44 g/mol
LogP32.30
Rot. Bonds23

About 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide

3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide (PubChem CID 158869420) has the molecular formula C140H103Cl2F4N25O and a molecular weight of 2298.44 g/mol. Its IUPAC name is 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide.

Molecular Properties

Compound Name3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide
PubChem CID158869420
Molecular FormulaC140H103Cl2F4N25O
Molecular Weight2298.44 g/mol
Exact Mass2295.81
IUPAC Name3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide
SMILESCc1cc(-c2ncccc2-c2ccc3ncnc(NCCc4cccnc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(NCc4ccncc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(Nc4cccc(C(N)=O)c4)c3c2)ccc1F.Clc1cccc(-c2ncccc2-c2cnc3ncccc3c2)c1.Fc1ccc(-c2ncccc2-c2cnc3ncccc3c2)cc1Cl.Nc1ncnc2ccc(-c3cccnc3-c3cccc(C4CC4)c3)cc12
InChIInChI=1S/C27H20FN5O.C27H22FN5.C26H20FN5.C22H18N4.C19H11ClFN3.C19H12ClN3/c1-16-12-18(7-9-23(16)28)25-21(6-3-11-30-25)17-8-10-24-22(14-17)27(32-15-31-24)33-20-5-2-4-19(13-20)26(29)34;1-18-14-21(6-8-24(18)28)26-22(5-3-12-30-26)20-7-9-25-23(15-20)27(33-17-32-25)31-13-10-19-4-2-11-29-16-19;1-17-13-20(4-6-23(17)27)25-21(3-2-10-29-25)19-5-7-24-22(14-19)26(32-16-31-24)30-15-18-8-11-28-12-9-18;23-22-19-12-16(8-9-20(19)25-13-26-22)18-5-2-10-24-21(18)17-4-1-3-15(11-17)14-6-7-14;20-16-10-12(5-6-17(16)21)18-15(4-2-7-22-18)14-9-13-3-1-8-23-19(13)24-11-14;20-16-6-1-4-13(11-16)18-17(7-3-8-21-18)15-10-14-5-2-9-22-19(14)23-12-15/h2-15H,1H3,(H2,29,34)(H,31,32,33);2-9,11-12,14-17H,10,13H2,1H3,(H,31,32,33);2-14,16H,15H2,1H3,(H,30,31,32);1-5,8-14H,6-7H2,(H2,23,25,26);1-11H;1-12H
InChIKeyJBQPLKDPLTVTGF-UHFFFAOYSA-N
XLogP32.30
TPSA363.00 Ų
H-Bond Donors5
H-Bond Acceptors25
Rotatable Bonds23
Heavy Atoms172
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002298.44
LogP ≤ 532.30
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1025

Analyze 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide with MolForge

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Related Compounds

US10927111, Example 64
CID 155253596
US10927111, Example 33
CID 155253675
N-[4-({[7-(2-chloropyridin-3-yl)-2-(dimethylamino)quinazolin-4-yl]amino}methyl)phenyl]-4-fluorobenzamide
CID 25026310
4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3-chloro-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide
CID 134264537
4-chloro-N-[4-({[2-(4-pyrimidin-2-ylpiperazin-1-yl)-6-(trifluoromethyl)quinazolin-4-yl]amino}methyl)phenyl]benzamide
CID 68943951
3-[4-[[6-[Bis(4-chlorophenyl)methyl]quinazolin-4-yl]amino]piperidin-1-yl]benzamide
CID 118916154
US10023557, Example 195
CID 124182091
4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3-chloro-N-(pyridin-2-yl)benzamide
CID 134264601
4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-2-chloro-N-(pyridin-2-yl)benzamide
CID 134264765
4-(8-(3-acrylamidophenyl)quinazolin-6-yl)-3-chloro-N-(4-cyclopropylpyridin-2-yl)benzamide
CID 134265375
3-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]-N-[2-(dimethylamino)ethyl]benzamide
CID 53346154
6-chloro-N-[2-(4,4-difluoropiperidin-1-yl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethyl]-2-(4-propan-2-ylpiperazin-1-yl)quinoline-5-carboxamide
CID 58227985

Frequently Asked Questions

What is the IUPAC name of 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide?
The IUPAC name of 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide (CID 158869420) is 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide.
What is the SMILES notation for 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide?
The canonical SMILES for 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide is Cc1cc(-c2ncccc2-c2ccc3ncnc(NCCc4cccnc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(NCc4ccncc4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(Nc4cccc(C(N)=O)c4)c3c2)ccc1F.Clc1cccc(-c2ncccc2-c2cnc3ncccc3c2)c1.Fc1ccc(-c2ncccc2-c2cnc3ncccc3c2)cc1Cl.Nc1ncnc2ccc(-c3cccnc3-c3cccc(C4CC4)c3)cc12.
What is the InChIKey of 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide?
The InChIKey is JBQPLKDPLTVTGF-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H20FN5O.C27H22FN5.C26H20FN5.C22H18N4.C19H11ClFN3.C19H12ClN3/c1-16-12-18(7-9-23(16)28)25-21(6-3-11-30-25)17-8-10-24-22(14-17)27(32-15-31-24)33-20-5-2-4-19(13-20)26(29)34;1-18-14-21(6-8-24(18)28)26-22(5-3-12-30-26)20-7-9-25-23(15-20)27(33-17-32-25)31-13-10-19-4-2-11-29-16-19;1-17-13-20(4-6-23(17)27)25-21(3-2-10-29-25)19-5-7-24-22(14-19)26(32-16-31-24)30-15-18-8-11-28-12-9-18;23-22-19-12-16(8-9-20(19)25-13-26-22)18-5-2-10-24-21(18)17-4-1-3-15(11-17)14-6-7-14;20-16-10-12(5-6-17(16)21)18-15(4-2-7-22-18)14-9-13-3-1-8-23-19(13)24-11-14;20-16-6-1-4-13(11-16)18-17(7-3-8-21-18)15-10-14-5-2-9-22-19(14)23-12-15/h2-15H,1H3,(H2,29,34)(H,31,32,33);2-9,11-12,14-17H,10,13H2,1H3,(H,31,32,33);2-14,16H,15H2,1H3,(H,30,31,32);1-5,8-14H,6-7H2,(H2,23,25,26);1-11H;1-12H.
What are the key properties of 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide?
3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide has a molecular weight of 2298.44 g/mol, XLogP of 32.30, 23 rotatable bonds, 5 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(3-chlorophenyl)-3-pyridinyl]-1,8-naphthyridine;6-[2-(3-cyclopropylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(2-pyridin-3-ylethyl)quinazolin-4-amine;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(pyridin-4-ylmethyl)quinazolin-4-amine;3-[[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-yl]amino]benzamide is sourced from PubChem (CID 158869420), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).