1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one

C74H69ClF3N21O4 — CID 158965249

IUPAC1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
SMILESCCn1cc(-c2cccc(N3CCN(c4ccc(C(F)(F)F)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(Cl)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(OC)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1
InChIInChI=1S/C25H22F3N7O.C25H25N7O2.C24H22ClN7O/c1-2-33-15-20(22(32-33)21-10-11-30-23(29)31-21)16-4-3-5-19(14-16)35-13-12-34(24(35)36)18-8-6-17(7-9-18)25(26,27)28;1-3-30-16-21(23(29-30)22-11-12-27-24(26)28-22)17-5-4-6-19(15-17)32-14-13-31(25(32)33)18-7-9-20(34-2)10-8-18;1-2-30-15-20(22(29-30)21-10-11-27-23(26)28-21)16-4-3-5-19(14-16)32-13-12-31(24(32)33)18-8-6-17(25)7-9-18/h3-11,14-15H,2,12-13H2,1H3,(H2,29,30,31);4-12,15-16H,3,13-14H2,1-2H3,(H2,26,27,28);3-11,14-15H,2,12-13H2,1H3,(H2,26,27,28)
InChIKeyJNCSODNALNBQPX-UHFFFAOYSA-N
MW1408.96 g/mol
LogP13.85
Rot. Bonds16

About 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one

1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one (PubChem CID 158965249) has the molecular formula C74H69ClF3N21O4 and a molecular weight of 1408.96 g/mol. Its IUPAC name is 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one.

Molecular Properties

Compound Name1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
PubChem CID158965249
Molecular FormulaC74H69ClF3N21O4
Molecular Weight1408.96 g/mol
Exact Mass1407.55
IUPAC Name1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
SMILESCCn1cc(-c2cccc(N3CCN(c4ccc(C(F)(F)F)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(Cl)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(OC)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1
InChIInChI=1S/C25H22F3N7O.C25H25N7O2.C24H22ClN7O/c1-2-33-15-20(22(32-33)21-10-11-30-23(29)31-21)16-4-3-5-19(14-16)35-13-12-34(24(35)36)18-8-6-17(7-9-18)25(26,27)28;1-3-30-16-21(23(29-30)22-11-12-27-24(26)28-22)17-5-4-6-19(15-17)32-14-13-31(25(32)33)18-7-9-20(34-2)10-8-18;1-2-30-15-20(22(29-30)21-10-11-27-23(26)28-21)16-4-3-5-19(14-16)32-13-12-31(24(32)33)18-8-6-17(25)7-9-18/h3-11,14-15H,2,12-13H2,1H3,(H2,29,30,31);4-12,15-16H,3,13-14H2,1-2H3,(H2,26,27,28);3-11,14-15H,2,12-13H2,1H3,(H2,26,27,28)
InChIKeyJNCSODNALNBQPX-UHFFFAOYSA-N
XLogP13.85
TPSA288.74 Ų
H-Bond Donors3
H-Bond Acceptors19
Rotatable Bonds16
Heavy Atoms103
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001408.96
LogP ≤ 513.85
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1019

Analyze 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(4-chlorophenyl)-6-(6-fluoro-2-methylbenzimidazol-1-yl)pyrazin-2-amine;1-[6-[4-(difluoromethoxy)-3-fluoroanilino]pyrazin-2-yl]-N-[4-(difluoromethoxy)-3-fluorophenyl]-2-ethylimidazo[4,5-b]pyridin-6-amine;6-(2-ethyl-5-fluoropyrazolo[1,5-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine;6-(6-fluoro-2-methylbenzimidazol-1-yl)-N-(4-methylphenyl)pyrazin-2-amine
CID 157131555
1-(4-chlorophenyl)-3-[2-fluoro-3-(2-morpholin-4-yl-4-pyridin-4-yl-1H-imidazol-5-yl)phenyl]urea;1-[2-fluoro-3-(2-morpholin-4-yl-4-pyridin-4-yl-1H-imidazol-5-yl)phenyl]-3-(4-methoxyphenyl)urea;1-[2-fluoro-3-(2-morpholin-4-yl-4-pyridin-4-yl-1H-imidazol-5-yl)phenyl]-3-(4-methylphenyl)urea;1-[2-fluoro-3-(2-morpholin-4-yl-4-pyridin-4-yl-1H-imidazol-5-yl)phenyl]-3-[4-(trifluoromethyl)phenyl]urea
CID 157248577
4-(2-Chloropyrimidin-4-yl)oxyaniline;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[2-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyphenyl]urea;2,4-dichloropyrimidine;4-[2-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyaniline
CID 157344788
6-(5-chloro-2-ethylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(difluoromethoxy)phenyl]pyrimidine-2,4-diamine;6-(5-chloro-2-ethylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine;6-(5-chloro-2-methylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(difluoromethoxy)phenyl]pyrimidine-2,4-diamine;6-(5-chloro-2-methylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine;6-(2-cyclopropylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine;6-(2-ethylbenzimidazol-1-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine
CID 157437117
1-[3-[4-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-5-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-5-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-5-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
CID 157636901
4-Chloro-6-(1-methylpyrazol-4-yl)pyrimidine;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-fluoro-4-[6-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyphenyl]urea;2-fluoro-4-[6-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyaniline
CID 158190011
4-Chloro-6-(1-methylpyrazol-4-yl)pyrimidine;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-[6-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyphenyl]urea;4-[6-(1-methylpyrazol-4-yl)pyrimidin-4-yl]oxyaniline
CID 158328705
6-(5-chloro-2-cyclopropylbenzimidazol-1-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine;6-(6-chloro-2-cyclopropylbenzimidazol-1-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine;6-(2-cyclopropylbenzimidazol-1-yl)-2-N-[4-(difluoromethoxy)phenyl]pyrimidine-2,4-diamine;2-N-[4-(difluoromethoxy)phenyl]-6-[2-(difluoromethyl)benzimidazol-1-yl]pyrimidine-2,4-diamine;2-N-[4-(difluoromethoxy)phenyl]-6-(2-propan-2-ylbenzimidazol-1-yl)pyrimidine-2,4-diamine;6-(2-ethylpyrazolo[1,5-a]pyridin-3-yl)-2-N-[4-(trifluoromethyl)phenyl]pyrimidine-2,4-diamine
CID 158341103
1-[5-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)-2-fluorophenyl]-3-(4-chlorophenyl)urea;1-[5-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)-2-fluorophenyl]-3-(4-methoxyphenyl)urea;1-[5-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)-2-fluorophenyl]-3-(4-methylphenyl)urea;1-[5-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)-2-fluorophenyl]-3-[4-(trifluoromethyl)phenyl]urea
CID 158445648
1-[3-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenyl]-3-(4-chlorophenyl)urea;1-[3-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenyl]-3-(4-methoxyphenyl)urea;1-[3-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenyl]-3-(4-methylphenyl)urea;1-[3-(2-tert-butyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenyl]-3-[4-(trifluoromethyl)phenyl]urea
CID 158811812
1-[1-(3-Chloro-5-methylphenyl)imidazol-2-yl]-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea;1-[1-(4-ethylphenyl)imidazol-2-yl]-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea;1-[1-(4-methylphenyl)imidazol-2-yl]-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea;1-[4-[1-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]-3-[1-(2-propan-2-ylphenyl)imidazol-2-yl]urea;1-(1-phenylimidazol-2-yl)-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea;1-(1-pyridin-2-ylimidazol-2-yl)-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea;1-(1-pyridin-4-ylimidazol-2-yl)-3-[4-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]phenyl]urea
CID 158845296
4,5-dimethyl-1-(3-methylbenzene-6-id-1-yl)-3-(3-methylphenyl)-2H-imidazol-3-ium-2-ide;4,5-dimethyl-1-(3-methylbenzene-6-id-1-yl)-3-phenyl-2H-imidazol-3-ium-2-ide;tris(iridium);tetrakis(1-(4-methoxybenzene-6-id-1-yl)-3-(4-methoxyphenyl)-4,5-dimethyl-2H-imidazol-3-ium-2-ide);2-(5-methyl-1,4-diaza-2-azanidacyclopenta-3,5-dien-3-yl)pyridine;2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)pyridine;2-[3-(trifluoromethyl)pyrazol-1-id-5-yl]pyridine
CID 159081755

Frequently Asked Questions

What is the IUPAC name of 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one?
The IUPAC name of 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one (CID 158965249) is 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one.
What is the SMILES notation for 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one?
The canonical SMILES for 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one is CCn1cc(-c2cccc(N3CCN(c4ccc(C(F)(F)F)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(Cl)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.CCn1cc(-c2cccc(N3CCN(c4ccc(OC)cc4)C3=O)c2)c(-c2ccnc(N)n2)n1.
What is the InChIKey of 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one?
The InChIKey is JNCSODNALNBQPX-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22F3N7O.C25H25N7O2.C24H22ClN7O/c1-2-33-15-20(22(32-33)21-10-11-30-23(29)31-21)16-4-3-5-19(14-16)35-13-12-34(24(35)36)18-8-6-17(7-9-18)25(26,27)28;1-3-30-16-21(23(29-30)22-11-12-27-24(26)28-22)17-5-4-6-19(15-17)32-14-13-31(25(32)33)18-7-9-20(34-2)10-8-18;1-2-30-15-20(22(29-30)21-10-11-27-23(26)28-21)16-4-3-5-19(14-16)32-13-12-31(24(32)33)18-8-6-17(25)7-9-18/h3-11,14-15H,2,12-13H2,1H3,(H2,29,30,31);4-12,15-16H,3,13-14H2,1-2H3,(H2,26,27,28);3-11,14-15H,2,12-13H2,1H3,(H2,26,27,28).
What are the key properties of 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one?
1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one has a molecular weight of 1408.96 g/mol, XLogP of 13.85, 16 rotatable bonds, 3 hydrogen bond donors, and 19 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-(4-methoxyphenyl)imidazolidin-2-one;1-[3-[3-(2-aminopyrimidin-4-yl)-1-ethylpyrazol-4-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one is sourced from PubChem (CID 158965249), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).