6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide

C190H169F27N36O32 — CID 159015053

IUPAC6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
SMILESCC(C)CN1CCN(CCOc2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1ccn[nH]1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(O)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(OCCN2CCCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OC2CCOCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCCCCO)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(-c2cncnc2)c1
InChIInChI=1S/C28H32F3N5O3.C24H23F3N4O3.C22H19F3N4O4.C22H21F3N4O4.C20H17F3N4O4.C19H17F3N4O4.C19H15F3N4O4.C18H13F3N4O3.C18H12F3N3O3/c1-20(2)18-36-11-9-35(10-12-36)13-14-38-26-8-3-21(15-25(26)22-16-32-19-33-17-22)27(37)34-23-4-6-24(7-5-23)39-28(29,30)31;25-24(26,27)34-20-6-4-19(5-7-20)30-23(32)17-3-8-22(33-12-11-31-9-1-2-10-31)21(13-17)18-14-28-16-29-15-18;23-22(24,25)33-18-3-1-16(2-4-18)29-20(30)14-9-19(15-10-26-13-27-11-15)21(28-12-14)32-17-5-7-31-8-6-17;23-22(24,25)33-18-6-4-17(5-7-18)29-20(31)15-10-19(16-11-26-14-27-12-16)21(28-13-15)32-9-3-1-2-8-30;1-29-6-7-30-19-17(14-9-24-12-25-10-14)8-13(11-26-19)18(28)27-15-2-4-16(5-3-15)31-20(21,22)23;1-28-8-9-29-18-15(16-6-7-24-26-16)10-12(11-23-18)17(27)25-13-2-4-14(5-3-13)30-19(20,21)22;20-19(21,22)30-15-3-1-14(2-4-15)26-17(28)12-7-16(13-8-23-11-24-9-13)18(25-10-12)29-6-5-27;1-27-17-15(12-7-22-10-23-8-12)6-11(9-24-17)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)27-14-4-2-13(3-5-14)24-17(26)11-1-6-16(25)15(7-11)12-8-22-10-23-9-12/h3-8,15-17,19-20H,9-14,18H2,1-2H3,(H,34,37);3-8,13-16H,1-2,9-12H2,(H,30,32);1-4,9-13,17H,5-8H2,(H,29,30);4-7,10-14,30H,1-3,8-9H2,(H,29,31);2-5,8-12H,6-7H2,1H3,(H,27,28);2-7,10-11H,8-9H2,1H3,(H,24,26)(H,25,27);1-4,7-11,27H,5-6H2,(H,26,28);2-10H,1H3,(H,25,26);1-10,25H,(H,24,26)
InChIKeyJSZFMEUJYQYQKG-UHFFFAOYSA-N
MW3981.61 g/mol
LogP36.32
Rot. Bonds66

About 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide

6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide (PubChem CID 159015053) has the molecular formula C190H169F27N36O32 and a molecular weight of 3981.61 g/mol. Its IUPAC name is 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide.

Molecular Properties

Compound Name6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
PubChem CID159015053
Molecular FormulaC190H169F27N36O32
Molecular Weight3981.61 g/mol
Exact Mass3979.23
IUPAC Name6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
SMILESCC(C)CN1CCN(CCOc2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1ccn[nH]1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(O)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(OCCN2CCCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OC2CCOCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCCCCO)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(-c2cncnc2)c1
InChIInChI=1S/C28H32F3N5O3.C24H23F3N4O3.C22H19F3N4O4.C22H21F3N4O4.C20H17F3N4O4.C19H17F3N4O4.C19H15F3N4O4.C18H13F3N4O3.C18H12F3N3O3/c1-20(2)18-36-11-9-35(10-12-36)13-14-38-26-8-3-21(15-25(26)22-16-32-19-33-17-22)27(37)34-23-4-6-24(7-5-23)39-28(29,30)31;25-24(26,27)34-20-6-4-19(5-7-20)30-23(32)17-3-8-22(33-12-11-31-9-1-2-10-31)21(13-17)18-14-28-16-29-15-18;23-22(24,25)33-18-3-1-16(2-4-18)29-20(30)14-9-19(15-10-26-13-27-11-15)21(28-12-14)32-17-5-7-31-8-6-17;23-22(24,25)33-18-6-4-17(5-7-18)29-20(31)15-10-19(16-11-26-14-27-12-16)21(28-13-15)32-9-3-1-2-8-30;1-29-6-7-30-19-17(14-9-24-12-25-10-14)8-13(11-26-19)18(28)27-15-2-4-16(5-3-15)31-20(21,22)23;1-28-8-9-29-18-15(16-6-7-24-26-16)10-12(11-23-18)17(27)25-13-2-4-14(5-3-13)30-19(20,21)22;20-19(21,22)30-15-3-1-14(2-4-15)26-17(28)12-7-16(13-8-23-11-24-9-13)18(25-10-12)29-6-5-27;1-27-17-15(12-7-22-10-23-8-12)6-11(9-24-17)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)27-14-4-2-13(3-5-14)24-17(26)11-1-6-16(25)15(7-11)12-8-22-10-23-9-12/h3-8,15-17,19-20H,9-14,18H2,1-2H3,(H,34,37);3-8,13-16H,1-2,9-12H2,(H,30,32);1-4,9-13,17H,5-8H2,(H,29,30);4-7,10-14,30H,1-3,8-9H2,(H,29,31);2-5,8-12H,6-7H2,1H3,(H,27,28);2-7,10-11H,8-9H2,1H3,(H,24,26)(H,25,27);1-4,7-11,27H,5-6H2,(H,26,28);2-10H,1H3,(H,25,26);1-10,25H,(H,24,26)
InChIKeyJSZFMEUJYQYQKG-UHFFFAOYSA-N
XLogP36.32
TPSA829.17 Ų
H-Bond Donors13
H-Bond Acceptors58
Rotatable Bonds66
Heavy Atoms285
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003981.61
LogP ≤ 536.32
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1058

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Analyze 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide with MolForge

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Related Compounds

N-[4-[chloro(difluoro)methoxy]phenyl]-6-(oxan-4-yloxy)-5-pyrimidin-5-ylpyridine-3-carboxamide;6-ethoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(2,2,2-trifluoroethyl)phenyl]pyridine-3-carboxamide;methyl 2-pyrimidin-5-yl-4-[[4-(trifluoromethoxy)phenyl]carbamoyl]benzoate
CID 157381204
5-(3,4-dihydro-1H-isoquinolin-2-yl)-4-hydroxy-1-[3-(4-oxopentyl)phenyl]pentan-1-one;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-3-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-3-[[2-(hydroxymethyl)-4-methylpiperazin-1-yl]methyl]benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-3-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]benzamide;N-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-N-methyl-3-(oxan-4-ylmethyl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-5-phenyl-1H-pyrazole-4-carboxamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1,2,4-triazol-1-yl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxybenzamide
CID 157598358
N-[4-[chloro(difluoro)methoxy]phenyl]-6-(oxan-4-yloxy)-5-pyrimidin-5-ylpyridine-3-carboxamide;6-ethoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;methyl 2-pyrimidin-5-yl-4-[[4-(trifluoromethoxy)phenyl]carbamoyl]benzoate
CID 157932954
3-(5-acetylthiophen-2-yl)-4-methoxy-N-[4-(trifluoromethoxy)phenyl]benzamide;3-(1,3-benzodioxol-5-yl)-4-methoxy-N-[4-(trifluoromethoxy)phenyl]benzamide;3-(6-fluoro-3-pyridinyl)-4-methoxy-N-[4-(trifluoromethoxy)phenyl]benzamide;4-(2-hydroxyethoxy)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-methoxy-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-methoxy-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-methoxy-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-methoxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-(2-morpholin-4-ylethoxy)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 157983494
N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypiperidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3S)-3-hydroxypiperidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-hydroxypiperidin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[2-(hydroxymethyl)morpholin-4-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 158940017
4-(2-hydroxyethoxy)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 159238704
3-(5-acetylthiophen-2-yl)-4-methoxy-N-[4-(trifluoromethoxy)phenyl]benzamide;4-(2-hydroxyethoxy)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-(2-morpholin-4-ylethoxy)-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 159252762
CID 159382095
CID 159382095
N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-3-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]benzamide;N-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-N-methyl-3-(oxan-4-ylmethyl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1-methylsulfonylpiperidin-4-yl)oxybenzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-5-phenyl-1H-pyrazole-4-carboxamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1,2,4-triazol-1-yl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxybenzamide
CID 159516215
4-(1-acetylpiperidin-4-yl)oxy-N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-3-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]benzamide;N-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-N-methyl-3-(oxan-4-ylmethyl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1-methylpiperidin-4-yl)oxybenzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1-methylsulfonylpiperidin-4-yl)oxybenzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-5-phenyl-1H-pyrazole-4-carboxamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1-propan-2-ylpiperidin-4-yl)oxybenzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-(1,2,4-triazol-1-yl)benzamide;N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]-4-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxybenzamide
CID 159524128
N-[4-[chloro(difluoro)methoxy]phenyl]-6-(oxan-4-yloxy)-5-pyrimidin-5-ylpyridine-3-carboxamide;6-ethoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-hydroxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;methyl 2-pyrimidin-5-yl-4-[[4-(trifluoromethoxy)phenyl]carbamoyl]benzoate;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 160422147
6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-methoxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 160521268

Frequently Asked Questions

What is the IUPAC name of 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide?
The IUPAC name of 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide (CID 159015053) is 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide.
What is the SMILES notation for 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide?
The canonical SMILES for 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide is CC(C)CN1CCN(CCOc2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1ccn[nH]1.COCCOc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.COc1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncnc1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(O)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(OCCN2CCCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OC2CCOCC2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCCCCO)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(-c2cncnc2)c1.
What is the InChIKey of 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide?
The InChIKey is JSZFMEUJYQYQKG-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H32F3N5O3.C24H23F3N4O3.C22H19F3N4O4.C22H21F3N4O4.C20H17F3N4O4.C19H17F3N4O4.C19H15F3N4O4.C18H13F3N4O3.C18H12F3N3O3/c1-20(2)18-36-11-9-35(10-12-36)13-14-38-26-8-3-21(15-25(26)22-16-32-19-33-17-22)27(37)34-23-4-6-24(7-5-23)39-28(29,30)31;25-24(26,27)34-20-6-4-19(5-7-20)30-23(32)17-3-8-22(33-12-11-31-9-1-2-10-31)21(13-17)18-14-28-16-29-15-18;23-22(24,25)33-18-3-1-16(2-4-18)29-20(30)14-9-19(15-10-26-13-27-11-15)21(28-12-14)32-17-5-7-31-8-6-17;23-22(24,25)33-18-6-4-17(5-7-18)29-20(31)15-10-19(16-11-26-14-27-12-16)21(28-13-15)32-9-3-1-2-8-30;1-29-6-7-30-19-17(14-9-24-12-25-10-14)8-13(11-26-19)18(28)27-15-2-4-16(5-3-15)31-20(21,22)23;1-28-8-9-29-18-15(16-6-7-24-26-16)10-12(11-23-18)17(27)25-13-2-4-14(5-3-13)30-19(20,21)22;20-19(21,22)30-15-3-1-14(2-4-15)26-17(28)12-7-16(13-8-23-11-24-9-13)18(25-10-12)29-6-5-27;1-27-17-15(12-7-22-10-23-8-12)6-11(9-24-17)16(26)25-13-2-4-14(5-3-13)28-18(19,20)21;19-18(20,21)27-14-4-2-13(3-5-14)24-17(26)11-1-6-16(25)15(7-11)12-8-22-10-23-9-12/h3-8,15-17,19-20H,9-14,18H2,1-2H3,(H,34,37);3-8,13-16H,1-2,9-12H2,(H,30,32);1-4,9-13,17H,5-8H2,(H,29,30);4-7,10-14,30H,1-3,8-9H2,(H,29,31);2-5,8-12H,6-7H2,1H3,(H,27,28);2-7,10-11H,8-9H2,1H3,(H,24,26)(H,25,27);1-4,7-11,27H,5-6H2,(H,26,28);2-10H,1H3,(H,25,26);1-10,25H,(H,24,26).
What are the key properties of 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide?
6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide has a molecular weight of 3981.61 g/mol, XLogP of 36.32, 66 rotatable bonds, 13 hydrogen bond donors, and 58 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(2-hydroxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(5-hydroxypentoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-hydroxy-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(2-methoxyethoxy)-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-(2-methoxyethoxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-methoxy-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;4-[2-[4-(2-methylpropyl)piperazin-1-yl]ethoxy]-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;6-(oxan-4-yloxy)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;3-pyrimidin-5-yl-4-(2-pyrrolidin-1-ylethoxy)-N-[4-(trifluoromethoxy)phenyl]benzamide is sourced from PubChem (CID 159015053), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).