2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine

C227H277Br5N90O4 — CID 159036473

IUPAC2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
SMILESCC(C)n1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3Br)cnn12.CCn1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)c(Br)c(C4CCCNC4)nc23)cn1.N#Cc1cncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)c1.Nc1cc(C2CCCNC2)nc2c(-c3cccnc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccoc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(CCO)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4ccccn4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4cccnc4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnoc3)cnn12
InChIInChI=1S/C21H29BrN8O.C21H28BrN7.2C20H22N8.C17H21Br2N7.C17H22BrN7.C17H23N7.C17H17N7.C16H21N7O.C16H21N7.C16H18N6.C15H17N5O.C14H16N6O/c1-28-14-16(12-25-28)17-13-26-30-20(17)27-19(15-3-2-4-23-11-15)18(22)21(30)24-5-6-29-7-9-31-10-8-29;1-28-13-15(11-24-28)17-12-25-29-20(17)27-19(14-6-5-9-23-10-14)18(22)21(29)26-16-7-3-2-4-8-16;21-19-7-18(15-4-2-6-23-9-15)26-20-17(11-25-28(19)20)16-10-24-27(13-16)12-14-3-1-5-22-8-14;21-19-8-18(14-4-3-6-22-9-14)26-20-17(11-25-28(19)20)15-10-24-27(12-15)13-16-5-1-2-7-23-16;1-3-21-17-13(18)14(10-5-4-6-20-7-10)24-16-12(9-23-26(16)17)11-8-22-25(2)15(11)19;1-3-20-17-14(18)15(11-5-4-6-19-7-11)23-16-13(9-22-25(16)17)12-8-21-24(2)10-12;1-11(2)23-10-13(8-20-23)14-9-21-24-16(18)6-15(22-17(14)24)12-4-3-5-19-7-12;18-6-11-4-13(9-21-7-11)14-10-22-24-16(19)5-15(23-17(14)24)12-2-1-3-20-8-12;17-15-6-14(11-2-1-3-18-7-11)21-16-13(9-20-23(15)16)12-8-19-22(10-12)4-5-24;1-2-22-10-12(8-19-22)13-9-20-23-15(17)6-14(21-16(13)23)11-4-3-5-18-7-11;17-15-7-14(12-4-2-6-19-9-12)21-16-13(10-20-22(15)16)11-3-1-5-18-8-11;16-14-6-13(10-2-1-4-17-7-10)19-15-12(8-18-20(14)15)11-3-5-21-9-11;15-13-4-12(9-2-1-3-16-5-9)19-14-11(7-17-20(13)14)10-6-18-21-8-10/h12-15,23-24H,2-11H2,1H3;11-14,16,23,26H,2-10H2,1H3;1,3,5,7-8,10-11,13,15,23H,2,4,6,9,12,21H2;1-2,5,7-8,10-12,14,22H,3-4,6,9,13,21H2;8-10,20-21H,3-7H2,1-2H3;8-11,19-20H,3-7H2,1-2H3;6,8-12,19H,3-5,7,18H2,1-2H3;4-5,7,9-10,12,20H,1-3,8,19H2;6,8-11,18,24H,1-5,7,17H2;6,8-11,18H,2-5,7,17H2,1H3;1,3,5,7-8,10,12,19H,2,4,6,9,17H2;3,5-6,8-10,17H,1-2,4,7,16H2;4,6-9,16H,1-3,5,15H2
InChIKeyJVNBYBDFUAVXEC-UHFFFAOYSA-N
MW4729.86 g/mol
LogP28.27
Rot. Bonds44

About 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine

2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine (PubChem CID 159036473) has the molecular formula C227H277Br5N90O4 and a molecular weight of 4729.86 g/mol. Its IUPAC name is 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine.

Molecular Properties

Compound Name2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
PubChem CID159036473
Molecular FormulaC227H277Br5N90O4
Molecular Weight4729.86 g/mol
Exact Mass4722.02
IUPAC Name2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
SMILESCC(C)n1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3Br)cnn12.CCn1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)c(Br)c(C4CCCNC4)nc23)cn1.N#Cc1cncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)c1.Nc1cc(C2CCCNC2)nc2c(-c3cccnc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccoc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(CCO)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4ccccn4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4cccnc4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnoc3)cnn12
InChIInChI=1S/C21H29BrN8O.C21H28BrN7.2C20H22N8.C17H21Br2N7.C17H22BrN7.C17H23N7.C17H17N7.C16H21N7O.C16H21N7.C16H18N6.C15H17N5O.C14H16N6O/c1-28-14-16(12-25-28)17-13-26-30-20(17)27-19(15-3-2-4-23-11-15)18(22)21(30)24-5-6-29-7-9-31-10-8-29;1-28-13-15(11-24-28)17-12-25-29-20(17)27-19(14-6-5-9-23-10-14)18(22)21(29)26-16-7-3-2-4-8-16;21-19-7-18(15-4-2-6-23-9-15)26-20-17(11-25-28(19)20)16-10-24-27(13-16)12-14-3-1-5-22-8-14;21-19-8-18(14-4-3-6-22-9-14)26-20-17(11-25-28(19)20)15-10-24-27(12-15)13-16-5-1-2-7-23-16;1-3-21-17-13(18)14(10-5-4-6-20-7-10)24-16-12(9-23-26(16)17)11-8-22-25(2)15(11)19;1-3-20-17-14(18)15(11-5-4-6-19-7-11)23-16-13(9-22-25(16)17)12-8-21-24(2)10-12;1-11(2)23-10-13(8-20-23)14-9-21-24-16(18)6-15(22-17(14)24)12-4-3-5-19-7-12;18-6-11-4-13(9-21-7-11)14-10-22-24-16(19)5-15(23-17(14)24)12-2-1-3-20-8-12;17-15-6-14(11-2-1-3-18-7-11)21-16-13(9-20-23(15)16)12-8-19-22(10-12)4-5-24;1-2-22-10-12(8-19-22)13-9-20-23-15(17)6-14(21-16(13)23)11-4-3-5-18-7-11;17-15-7-14(12-4-2-6-19-9-12)21-16-13(10-20-22(15)16)11-3-1-5-18-8-11;16-14-6-13(10-2-1-4-17-7-10)19-15-12(8-18-20(14)15)11-3-5-21-9-11;15-13-4-12(9-2-1-3-16-5-9)19-14-11(7-17-20(13)14)10-6-18-21-8-10/h12-15,23-24H,2-11H2,1H3;11-14,16,23,26H,2-10H2,1H3;1,3,5,7-8,10-11,13,15,23H,2,4,6,9,12,21H2;1-2,5,7-8,10-12,14,22H,3-4,6,9,13,21H2;8-10,20-21H,3-7H2,1-2H3;8-11,19-20H,3-7H2,1-2H3;6,8-12,19H,3-5,7,18H2,1-2H3;4-5,7,9-10,12,20H,1-3,8,19H2;6,8-11,18,24H,1-5,7,17H2;6,8-11,18H,2-5,7,17H2,1H3;1,3,5,7-8,10,12,19H,2,4,6,9,17H2;3,5-6,8-10,17H,1-2,4,7,16H2;4,6-9,16H,1-3,5,15H2
InChIKeyJVNBYBDFUAVXEC-UHFFFAOYSA-N
XLogP28.27
TPSA1138.76 Ų
H-Bond Donors27
H-Bond Acceptors94
Rotatable Bonds44
Heavy Atoms326
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004729.86
LogP ≤ 528.27
H-Bond Donors ≤ 527
H-Bond Acceptors ≤ 1094

Analyze 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine?
The IUPAC name of 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine (CID 159036473) is 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine.
What is the SMILES notation for 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine?
The canonical SMILES for 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine is CC(C)n1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.CCNc1c(Br)c(C2CCCNC2)nc2c(-c3cnn(C)c3Br)cnn12.CCn1cc(-c2cnn3c(N)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)c(Br)c(C4CCCNC4)nc23)cn1.N#Cc1cncc(-c2cnn3c(N)cc(C4CCCNC4)nc23)c1.Nc1cc(C2CCCNC2)nc2c(-c3cccnc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3ccoc3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(CCO)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4ccccn4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnn(Cc4cccnc4)c3)cnn12.Nc1cc(C2CCCNC2)nc2c(-c3cnoc3)cnn12.
What is the InChIKey of 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine?
The InChIKey is JVNBYBDFUAVXEC-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H29BrN8O.C21H28BrN7.2C20H22N8.C17H21Br2N7.C17H22BrN7.C17H23N7.C17H17N7.C16H21N7O.C16H21N7.C16H18N6.C15H17N5O.C14H16N6O/c1-28-14-16(12-25-28)17-13-26-30-20(17)27-19(15-3-2-4-23-11-15)18(22)21(30)24-5-6-29-7-9-31-10-8-29;1-28-13-15(11-24-28)17-12-25-29-20(17)27-19(14-6-5-9-23-10-14)18(22)21(29)26-16-7-3-2-4-8-16;21-19-7-18(15-4-2-6-23-9-15)26-20-17(11-25-28(19)20)16-10-24-27(13-16)12-14-3-1-5-22-8-14;21-19-8-18(14-4-3-6-22-9-14)26-20-17(11-25-28(19)20)15-10-24-27(12-15)13-16-5-1-2-7-23-16;1-3-21-17-13(18)14(10-5-4-6-20-7-10)24-16-12(9-23-26(16)17)11-8-22-25(2)15(11)19;1-3-20-17-14(18)15(11-5-4-6-19-7-11)23-16-13(9-22-25(16)17)12-8-21-24(2)10-12;1-11(2)23-10-13(8-20-23)14-9-21-24-16(18)6-15(22-17(14)24)12-4-3-5-19-7-12;18-6-11-4-13(9-21-7-11)14-10-22-24-16(19)5-15(23-17(14)24)12-2-1-3-20-8-12;17-15-6-14(11-2-1-3-18-7-11)21-16-13(9-20-23(15)16)12-8-19-22(10-12)4-5-24;1-2-22-10-12(8-19-22)13-9-20-23-15(17)6-14(21-16(13)23)11-4-3-5-18-7-11;17-15-7-14(12-4-2-6-19-9-12)21-16-13(10-20-22(15)16)11-3-1-5-18-8-11;16-14-6-13(10-2-1-4-17-7-10)19-15-12(8-18-20(14)15)11-3-5-21-9-11;15-13-4-12(9-2-1-3-16-5-9)19-14-11(7-17-20(13)14)10-6-18-21-8-10/h12-15,23-24H,2-11H2,1H3;11-14,16,23,26H,2-10H2,1H3;1,3,5,7-8,10-11,13,15,23H,2,4,6,9,12,21H2;1-2,5,7-8,10-12,14,22H,3-4,6,9,13,21H2;8-10,20-21H,3-7H2,1-2H3;8-11,19-20H,3-7H2,1-2H3;6,8-12,19H,3-5,7,18H2,1-2H3;4-5,7,9-10,12,20H,1-3,8,19H2;6,8-11,18,24H,1-5,7,17H2;6,8-11,18H,2-5,7,17H2,1H3;1,3,5,7-8,10,12,19H,2,4,6,9,17H2;3,5-6,8-10,17H,1-2,4,7,16H2;4,6-9,16H,1-3,5,15H2.
What are the key properties of 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine?
2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine has a molecular weight of 4729.86 g/mol, XLogP of 28.27, 44 rotatable bonds, 27 hydrogen bond donors, and 94 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyrazol-1-yl]ethanol;5-(7-amino-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-3-yl)pyridine-3-carbonitrile;6-bromo-3-(5-bromo-1-methylpyrazol-4-yl)-N-ethyl-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclohexyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-ethyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-ethylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(furan-3-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1,2-oxazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-(1-propan-2-ylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-2-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-[1-(pyridin-3-ylmethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-amine;5-piperidin-3-yl-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine is sourced from PubChem (CID 159036473), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).