8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine

C65H61F3N16O3S — CID 159067957

About 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine

8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine (PubChem CID 159067957) has the molecular formula C65H61F3N16O3S and a molecular weight of 1203.37 g/mol. Its IUPAC name is 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 159067957
• Molecular Formula: C65H61F3N16O3S
• Molecular Weight: 1203.37 g/mol
• Exact Mass: 1202.48
• IUPAC Name: 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine
• SMILES: Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C4CC4)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccccn3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3nc(C)sc3C)c2n1
• InChI: InChI=1S/C23H23FN6O.C21H20FN5OS.C21H18FN5O/c1-13-12-30-22(27-13)17(20-9-19(14-3-4-14)28-29(20)2)11-26-23(30)25-10-16-15-7-8-31-21(15)6-5-18(16)24;1-11-10-27-20(25-11)16(19-12(2)29-13(3)26-19)9-24-21(27)23-8-15-14-6-7-28-18(14)5-4-17(15)22;1-13-12-27-20(26-13)16(18-4-2-3-8-23-18)11-25-21(27)24-10-15-14-7-9-28-19(14)6-5-17(15)22/h5-6,9,11-12,14H,3-4,7-8,10H2,1-2H3,(H,25,26);4-5,9-10H,6-8H2,1-3H3,(H,23,24);2-6,8,11-12H,7,9-10H2,1H3,(H,24,25)
• InChIKey: JZHHPDHQQOMKPA-UHFFFAOYSA-N
• XLogP: 12.25
• TPSA: 197.95 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 20
• Rotatable Bonds: 13
• Heavy Atoms: 88
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1203.37
LogP ≤ 5	12.25
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine (CID 159067957) is 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine is Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cc(C4CC4)nn3C)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccccn3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3nc(C)sc3C)c2n1.

What is the InChIKey of 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is JZHHPDHQQOMKPA-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23FN6O.C21H20FN5OS.C21H18FN5O/c1-13-12-30-22(27-13)17(20-9-19(14-3-4-14)28-29(20)2)11-26-23(30)25-10-16-15-7-8-31-21(15)6-5-18(16)24;1-11-10-27-20(25-11)16(19-12(2)29-13(3)26-19)9-24-21(27)23-8-15-14-6-7-28-18(14)5-4-17(15)22;1-13-12-27-20(26-13)16(18-4-2-3-8-23-18)11-25-21(27)24-10-15-14-7-9-28-19(14)6-5-17(15)22/h5-6,9,11-12,14H,3-4,7-8,10H2,1-2H3,(H,25,26);4-5,9-10H,6-8H2,1-3H3,(H,23,24);2-6,8,11-12H,7,9-10H2,1H3,(H,24,25).

What are the key properties of 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine?

8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1203.37 g/mol, XLogP of 12.25, 13 rotatable bonds, 3 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(3-cyclopropyl-1-methylpyrazol-5-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;8-(2,5-dimethyl-1,3-thiazol-4-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 159067957), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).