3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine

C98H72Cl5FN26 — CID 159106433

IUPAC3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine
SMILESCc1cc(-c2nc(C#N)c(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2nc(C#N)c(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1ccnc2c(Cl)cc(-c3ncc(N)nc3-c3ccc(F)cc3)cc12
InChIInChI=1S/C21H14ClN5.C20H14ClFN4.C20H15ClN4.C19H14ClN7.C18H15ClN6/c1-12-9-14(10-15-16(22)7-8-25-18(12)15)20-19(13-5-3-2-4-6-13)27-21(24)17(11-23)26-20;1-11-6-7-24-20-15(11)8-13(9-16(20)21)18-19(26-17(23)10-25-18)12-2-4-14(22)5-3-12;1-12-9-14(10-15-16(21)7-8-23-18(12)15)19-20(25-17(22)11-24-19)13-5-3-2-4-6-13;1-10-7-11(8-12-13(20)3-5-23-16(10)12)17-18(14-4-6-27(2)26-14)25-19(22)15(9-21)24-17;1-10-7-11(8-12-13(19)3-5-21-16(10)12)17-18(23-15(20)9-22-17)14-4-6-25(2)24-14/h2-10H,1H3,(H2,24,27);2-10H,1H3,(H2,23,26);2-11H,1H3,(H2,22,25);3-8H,1-2H3,(H2,22,25);3-9H,1-2H3,(H2,20,23)
InChIKeyKDYFVOLOSVGKHE-UHFFFAOYSA-N
MW1810.10 g/mol
LogP21.86
Rot. Bonds10

About 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine

3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine (PubChem CID 159106433) has the molecular formula C98H72Cl5FN26 and a molecular weight of 1810.10 g/mol. Its IUPAC name is 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine.

Molecular Properties

Compound Name3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine
PubChem CID159106433
Molecular FormulaC98H72Cl5FN26
Molecular Weight1810.10 g/mol
Exact Mass1806.49
IUPAC Name3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine
SMILESCc1cc(-c2nc(C#N)c(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2nc(C#N)c(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1ccnc2c(Cl)cc(-c3ncc(N)nc3-c3ccc(F)cc3)cc12
InChIInChI=1S/C21H14ClN5.C20H14ClFN4.C20H15ClN4.C19H14ClN7.C18H15ClN6/c1-12-9-14(10-15-16(22)7-8-25-18(12)15)20-19(13-5-3-2-4-6-13)27-21(24)17(11-23)26-20;1-11-6-7-24-20-15(11)8-13(9-16(20)21)18-19(26-17(23)10-25-18)12-2-4-14(22)5-3-12;1-12-9-14(10-15-16(21)7-8-23-18(12)15)19-20(25-17(22)11-24-19)13-5-3-2-4-6-13;1-10-7-11(8-12-13(20)3-5-23-16(10)12)17-18(14-4-6-27(2)26-14)25-19(22)15(9-21)24-17;1-10-7-11(8-12-13(19)3-5-21-16(10)12)17-18(23-15(20)9-22-17)14-4-6-25(2)24-14/h2-10H,1H3,(H2,24,27);2-10H,1H3,(H2,23,26);2-11H,1H3,(H2,22,25);3-8H,1-2H3,(H2,22,25);3-9H,1-2H3,(H2,20,23)
InChIKeyKDYFVOLOSVGKHE-UHFFFAOYSA-N
XLogP21.86
TPSA406.67 Ų
H-Bond Donors5
H-Bond Acceptors26
Rotatable Bonds10
Heavy Atoms130
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001810.10
LogP ≤ 521.86
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1026

Analyze 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine with MolForge

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Launch Full Analysis

Related Compounds

5-(8-Chloro-6-quinolinyl)-6-(1-methyl-1H-pyrazol-3-yl)-2-pyrazinamine
CID 137423685
3-Amino-6-(8-chloroquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile
CID 137423788
3-Amino-6-(8-chloroquinolin-6-yl)-5-(3-methylpyrazol-1-yl)pyrazine-2-carbonitrile
CID 137423835
2-[5-chloro-2-fluoro-3-[4-(3-pyridin-2-yl-1H-pyrazol-4-yl)quinolin-6-yl]phenyl]-N-pyridin-4-ylpteridin-4-amine
CID 136654835
5-(8-chloroquinolin-6-yl)-3-N-[(4-fluorophenyl)methyl]-6-(1-methylpyrazol-3-yl)pyrazine-2,3-diamine
CID 137430573
5-(8-chloroquinolin-6-yl)-3-N-[(4-fluorophenyl)methyl]-6-(3-methylpyrazol-1-yl)pyrazine-2,3-diamine
CID 137430581
5-(8-Chloroquinolin-6-yl)-6-(3-fluoropyrazol-1-yl)pyrazin-2-amine
CID 137430848
5-(8-Chloroquinolin-6-yl)-3-fluoro-6-(1-methylpyrazol-3-yl)pyrazin-2-amine
CID 137431194
5-(8-Chloroquinolin-6-yl)-6-(1-methylpyrazol-3-yl)-3-(trifluoromethyl)pyrazin-2-amine
CID 137431195
5-(8-chloroquinolin-6-yl)-6-(1-methylpyrazol-3-yl)-3-N-[2-[3-(trifluoromethyl)pyrrol-1-yl]ethyl]pyrazine-2,3-diamine
CID 137431278
5-(8-Chloroquinolin-6-yl)-6-(4-fluorophenyl)-3-[2-[(1-methylpyrazol-3-yl)amino]ethyl]pyrazin-2-amine
CID 154604507
5-(8-Chloroquinolin-6-yl)-6-(4-fluorophenyl)-3-[2-[(1-propan-2-ylpyrazol-3-yl)amino]ethyl]pyrazin-2-amine
CID 154604583

Frequently Asked Questions

What is the IUPAC name of 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine?
The IUPAC name of 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine (CID 159106433) is 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine.
What is the SMILES notation for 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine?
The canonical SMILES for 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine is Cc1cc(-c2nc(C#N)c(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2nc(C#N)c(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccccc2)cc2c(Cl)ccnc12.Cc1cc(-c2ncc(N)nc2-c2ccn(C)n2)cc2c(Cl)ccnc12.Cc1ccnc2c(Cl)cc(-c3ncc(N)nc3-c3ccc(F)cc3)cc12.
What is the InChIKey of 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine?
The InChIKey is KDYFVOLOSVGKHE-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H14ClN5.C20H14ClFN4.C20H15ClN4.C19H14ClN7.C18H15ClN6/c1-12-9-14(10-15-16(22)7-8-25-18(12)15)20-19(13-5-3-2-4-6-13)27-21(24)17(11-23)26-20;1-11-6-7-24-20-15(11)8-13(9-16(20)21)18-19(26-17(23)10-25-18)12-2-4-14(22)5-3-12;1-12-9-14(10-15-16(21)7-8-23-18(12)15)19-20(25-17(22)11-24-19)13-5-3-2-4-6-13;1-10-7-11(8-12-13(20)3-5-23-16(10)12)17-18(14-4-6-27(2)26-14)25-19(22)15(9-21)24-17;1-10-7-11(8-12-13(19)3-5-21-16(10)12)17-18(23-15(20)9-22-17)14-4-6-25(2)24-14/h2-10H,1H3,(H2,24,27);2-10H,1H3,(H2,23,26);2-11H,1H3,(H2,22,25);3-8H,1-2H3,(H2,22,25);3-9H,1-2H3,(H2,20,23).
What are the key properties of 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine?
3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine has a molecular weight of 1810.10 g/mol, XLogP of 21.86, 10 rotatable bonds, 5 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for 3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-(1-methylpyrazol-3-yl)pyrazine-2-carbonitrile;3-amino-6-(4-chloro-8-methylquinolin-6-yl)-5-phenylpyrazine-2-carbonitrile;5-(8-chloro-4-methylquinolin-6-yl)-6-(4-fluorophenyl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-(1-methylpyrazol-3-yl)pyrazin-2-amine;5-(4-chloro-8-methylquinolin-6-yl)-6-phenylpyrazin-2-amine is sourced from PubChem (CID 159106433), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).