6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C136H120Cl3F13N28O12S6 — CID 159118296

About 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 159118296) has the molecular formula C136H120Cl3F13N28O12S6 and a molecular weight of 2884.37 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 159118296
• Molecular Formula: C136H120Cl3F13N28O12S6
• Molecular Weight: 2884.37 g/mol
• Exact Mass: 2880.68
• IUPAC Name: 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCC3)c2cc1Cl.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2cc1Cl.Cc1cc2c(C#N)c(-c3ncc(S(=O)(=O)NC(C)C)cn3)n(C3CCC3)c2cc1Cl.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2-c1ccccn1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1
• InChI: InChI=1S/C25H20F3N5O2S.C23H18F3N5O2S.C23H19F2N5O2S.C22H20ClF3N4O2S.C22H21ClF2N4O2S.C21H22ClN5O2S/c1-15(25(26,27)28)32-36(34,35)18-8-10-21(31-14-18)24-20(13-29)19-9-7-17(16-5-6-16)12-22(19)33(24)23-4-2-3-11-30-23;1-14-6-9-20-17(11-14)18(12-27)22(31(20)21-5-3-4-10-28-21)19-8-7-16(13-29-19)34(32,33)30-15(2)23(24,25)26;1-15-5-8-21-18(10-15)19(13-26)23(30(21)22-4-2-3-9-27-22)20-7-6-17(14-28-20)33(31,32)29-16(11-24)12-25;1-12-8-16-17(10-27)21(30(14-4-3-5-14)20(16)9-18(12)23)19-7-6-15(11-28-19)33(31,32)29-13(2)22(24,25)26;1-13-7-17-18(11-26)22(29(15-3-2-4-15)21(17)8-19(13)23)20-6-5-16(12-27-20)32(30,31)28-14(9-24)10-25;1-12(2)26-30(28,29)15-10-24-21(25-11-15)20-17(9-23)16-7-13(3)18(22)8-19(16)27(20)14-5-4-6-14/h2-4,7-12,14-16,32H,5-6H2,1H3;3-11,13,15,30H,1-2H3;2-10,14,16,29H,11-12H2,1H3;6-9,11,13-14,29H,3-5H2,1-2H3;5-8,12,14-15,28H,2-4,9-10H2,1H3;7-8,10-12,14,26H,4-6H2,1-3H3/t2*15-;;13-;;/m00.0../s1
• InChIKey: KFIZJNIEYJWJMM-XKKHOOSCSA-N
• XLogP: 28.10
• TPSA: 578.24 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 34
• Rotatable Bonds: 35
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2884.37
LogP ≤ 5	28.10
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 159118296) is 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(C3CCC3)c2cc1Cl.Cc1cc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCC3)c2cc1Cl.Cc1cc2c(C#N)c(-c3ncc(S(=O)(=O)NC(C)C)cn3)n(C3CCC3)c2cc1Cl.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2-c1ccccn1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2-c1ccccn1.

What is the InChIKey of 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is KFIZJNIEYJWJMM-XKKHOOSCSA-N. The full InChI is InChI=1S/C25H20F3N5O2S.C23H18F3N5O2S.C23H19F2N5O2S.C22H20ClF3N4O2S.C22H21ClF2N4O2S.C21H22ClN5O2S/c1-15(25(26,27)28)32-36(34,35)18-8-10-21(31-14-18)24-20(13-29)19-9-7-17(16-5-6-16)12-22(19)33(24)23-4-2-3-11-30-23;1-14-6-9-20-17(11-14)18(12-27)22(31(20)21-5-3-4-10-28-21)19-8-7-16(13-29-19)34(32,33)30-15(2)23(24,25)26;1-15-5-8-21-18(10-15)19(13-26)23(30(21)22-4-2-3-9-27-22)20-7-6-17(14-28-20)33(31,32)29-16(11-24)12-25;1-12-8-16-17(10-27)21(30(14-4-3-5-14)20(16)9-18(12)23)19-7-6-15(11-28-19)33(31,32)29-13(2)22(24,25)26;1-13-7-17-18(11-26)22(29(15-3-2-4-15)21(17)8-19(13)23)20-6-5-16(12-27-20)32(30,31)28-14(9-24)10-25;1-12(2)26-30(28,29)15-10-24-21(25-11-15)20-17(9-23)16-7-13(3)18(22)8-19(16)27(20)14-5-4-6-14/h2-4,7-12,14-16,32H,5-6H2,1H3;3-11,13,15,30H,1-2H3;2-10,14,16,29H,11-12H2,1H3;6-9,11,13-14,29H,3-5H2,1-2H3;5-8,12,14-15,28H,2-4,9-10H2,1H3;7-8,10-12,14,26H,4-6H2,1-3H3/t2*15-;;13-;;/m00.0../s1.

What are the key properties of 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2884.37 g/mol, XLogP of 28.10, 35 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-5-methyl-1-pyridin-2-ylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 159118296), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).