N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide

C118H125Cl6F2N25O11 — CID 159138753

About N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide

N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide (PubChem CID 159138753) has the molecular formula C118H125Cl6F2N25O11 and a molecular weight of 2320.18 g/mol. Its IUPAC name is N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide.

Molecular Properties

• Compound Name: N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide
• PubChem CID: 159138753
• Molecular Formula: C118H125Cl6F2N25O11
• Molecular Weight: 2320.18 g/mol
• Exact Mass: 2315.81
• IUPAC Name: N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide
• SMILES: C[C@@](O)(CC(=O)Nc1nc2cc(Cl)c(Cl)nc2n1C1CCC1)c1ccccc1.C[C@@](O)(CC(=O)Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cc1)c1ccccn1.Cc1cc2nc(NC(=O)C[C@@](C)(O)c3ccccc3)n(C3CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C3CCC3)c2nc1Cl.Cc1ccc2nc(NC(=O)CC(C)(C)O)n(-c3ccc(F)cc3)c2n1.Cc1nc2c(cc1Cl)nc(NC(=O)CC(C)(C)C)n2C1CCC1
• InChI: InChI=1S/C21H17ClFN5O2.2C21H23ClN4O2.C20H20Cl2N4O2.C18H19FN4O2.C17H23ClN4O/c1-21(30,16-4-2-3-11-24-16)12-18(29)27-20-25-15-9-10-17(22)26-19(15)28(20)14-7-5-13(23)6-8-14;2*1-13-11-16-19(25-18(13)22)26(15-9-6-10-15)20(23-16)24-17(27)12-21(2,28)14-7-4-3-5-8-14;1-20(28,12-6-3-2-4-7-12)11-16(27)24-19-23-15-10-14(21)17(22)25-18(15)26(19)13-8-5-9-13;1-11-4-9-14-16(20-11)23(13-7-5-12(19)6-8-13)17(21-14)22-15(24)10-18(2,3)25;1-10-12(18)8-13-15(19-10)22(11-6-5-7-11)16(20-13)21-14(23)9-17(2,3)4/h2-11,30H,12H2,1H3,(H,25,27,29);2*3-5,7-8,11,15,28H,6,9-10,12H2,1-2H3,(H,23,24,27);2-4,6-7,10,13,28H,5,8-9,11H2,1H3,(H,23,24,27);4-9,25H,10H2,1-3H3,(H,21,22,24);8,11H,5-7,9H2,1-4H3,(H,20,21,23)/t3*21-;20-;;/m1101../s1
• InChIKey: KHVGQFLRQGDRBH-WYUDGBJOSA-N
• XLogP: 24.71
• TPSA: 472.90 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 30
• Rotatable Bonds: 27
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2320.18
LogP ≤ 5	24.71
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide?

The IUPAC name of N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide (CID 159138753) is N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide.

What is the SMILES notation for N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide?

The canonical SMILES for N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide is C[C@@](O)(CC(=O)Nc1nc2cc(Cl)c(Cl)nc2n1C1CCC1)c1ccccc1.C[C@@](O)(CC(=O)Nc1nc2ccc(Cl)nc2n1-c1ccc(F)cc1)c1ccccn1.Cc1cc2nc(NC(=O)C[C@@](C)(O)c3ccccc3)n(C3CCC3)c2nc1Cl.Cc1cc2nc(NC(=O)C[C@](C)(O)c3ccccc3)n(C3CCC3)c2nc1Cl.Cc1ccc2nc(NC(=O)CC(C)(C)O)n(-c3ccc(F)cc3)c2n1.Cc1nc2c(cc1Cl)nc(NC(=O)CC(C)(C)C)n2C1CCC1.

What is the InChIKey of N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide?

The InChIKey is KHVGQFLRQGDRBH-WYUDGBJOSA-N. The full InChI is InChI=1S/C21H17ClFN5O2.2C21H23ClN4O2.C20H20Cl2N4O2.C18H19FN4O2.C17H23ClN4O/c1-21(30,16-4-2-3-11-24-16)12-18(29)27-20-25-15-9-10-17(22)26-19(15)28(20)14-7-5-13(23)6-8-14;2*1-13-11-16-19(25-18(13)22)26(15-9-6-10-15)20(23-16)24-17(27)12-21(2,28)14-7-4-3-5-8-14;1-20(28,12-6-3-2-4-7-12)11-16(27)24-19-23-15-10-14(21)17(22)25-18(15)26(19)13-8-5-9-13;1-11-4-9-14-16(20-11)23(13-7-5-12(19)6-8-13)17(21-14)22-15(24)10-18(2,3)25;1-10-12(18)8-13-15(19-10)22(11-6-5-7-11)16(20-13)21-14(23)9-17(2,3)4/h2-11,30H,12H2,1H3,(H,25,27,29);2*3-5,7-8,11,15,28H,6,9-10,12H2,1-2H3,(H,23,24,27);2-4,6-7,10,13,28H,5,8-9,11H2,1H3,(H,23,24,27);4-9,25H,10H2,1-3H3,(H,21,22,24);8,11H,5-7,9H2,1-4H3,(H,20,21,23)/t3*21-;20-;;/m1101../s1.

What are the key properties of N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide?

N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide has a molecular weight of 2320.18 g/mol, XLogP of 24.71, 27 rotatable bonds, 11 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for N-(6-chloro-3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;(3R)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3S)-N-(5-chloro-3-cyclobutyl-6-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;(3R)-N-[5-chloro-3-(4-fluorophenyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-pyridin-2-ylbutanamide;(3R)-N-(5,6-dichloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylbutanamide;N-[3-(4-fluorophenyl)-5-methylimidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-methylbutanamide is sourced from PubChem (CID 159138753), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).