6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one

C151H135N39O15S — CID 159151204

About 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one

6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one (PubChem CID 159151204) has the molecular formula C151H135N39O15S and a molecular weight of 2768.07 g/mol. Its IUPAC name is 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one.

Molecular Properties

• Compound Name: 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one
• PubChem CID: 159151204
• Molecular Formula: C151H135N39O15S
• Molecular Weight: 2768.07 g/mol
• Exact Mass: 2766.07
• IUPAC Name: 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one
• SMILES: CCOc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CCS(=O)c1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.COCC(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(CC(=O)C4CCOCC4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(N4CCN(C)C4=O)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(OCCN4CCCC4=O)cc23)ccc1Oc1ccn2ncnc2c1
• InChI: InChI=1S/C28H26N6O3.C27H25N7O3.C25H22N8O2.C25H22N6O3.C23H20N6O2S.C23H20N6O2/c1-18-12-21(3-5-26(18)37-22-6-9-34-27(15-22)30-17-32-34)33-28-23-13-19(2-4-24(23)29-16-31-28)14-25(35)20-7-10-36-11-8-20;1-18-13-19(4-7-24(18)37-21-8-10-34-25(15-21)29-17-31-34)32-27-22-14-20(5-6-23(22)28-16-30-27)36-12-11-33-9-2-3-26(33)35;1-16-11-17(3-6-22(16)35-19-7-8-33-23(13-19)27-15-29-33)30-24-20-12-18(4-5-21(20)26-14-28-24)32-10-9-31(2)25(32)34;1-16-9-18(4-6-23(16)34-20-7-8-31-24(12-20)27-15-29-31)30-25-21-11-17(10-19(32)13-33-2)3-5-22(21)26-14-28-25;1-3-32(30)18-5-6-20-19(12-18)23(26-13-24-20)28-16-4-7-21(15(2)10-16)31-17-8-9-29-22(11-17)25-14-27-29;1-3-30-17-5-6-20-19(11-17)23(26-13-24-20)28-16-4-7-21(15(2)10-16)31-18-8-9-29-22(12-18)25-14-27-29/h2-6,9,12-13,15-17,20H,7-8,10-11,14H2,1H3,(H,29,31,33);4-8,10,13-17H,2-3,9,11-12H2,1H3,(H,28,30,32);3-8,11-15H,9-10H2,1-2H3,(H,26,28,30);3-9,11-12,14-15H,10,13H2,1-2H3,(H,26,28,30);4-14H,3H2,1-2H3,(H,24,26,28);4-14H,3H2,1-2H3,(H,24,26,28)
• InChIKey: KJHUEVVSPKJLFA-UHFFFAOYSA-N
• XLogP: 27.80
• TPSA: 595.37 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 51
• Rotatable Bonds: 40
• Heavy Atoms: 206
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2768.07
LogP ≤ 5	27.80
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	51

Frequently Asked Questions

What is the IUPAC name of 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one?

The IUPAC name of 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one (CID 159151204) is 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one.

What is the SMILES notation for 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one?

The canonical SMILES for 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one is CCOc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.CCS(=O)c1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.COCC(=O)Cc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(CC(=O)C4CCOCC4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(N4CCN(C)C4=O)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(OCCN4CCCC4=O)cc23)ccc1Oc1ccn2ncnc2c1.

What is the InChIKey of 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one?

The InChIKey is KJHUEVVSPKJLFA-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H26N6O3.C27H25N7O3.C25H22N8O2.C25H22N6O3.C23H20N6O2S.C23H20N6O2/c1-18-12-21(3-5-26(18)37-22-6-9-34-27(15-22)30-17-32-34)33-28-23-13-19(2-4-24(23)29-16-31-28)14-25(35)20-7-10-36-11-8-20;1-18-13-19(4-7-24(18)37-21-8-10-34-25(15-21)29-17-31-34)32-27-22-14-20(5-6-23(22)28-16-30-27)36-12-11-33-9-2-3-26(33)35;1-16-11-17(3-6-22(16)35-19-7-8-33-23(13-19)27-15-29-33)30-24-20-12-18(4-5-21(20)26-14-28-24)32-10-9-31(2)25(32)34;1-16-9-18(4-6-23(16)34-20-7-8-31-24(12-20)27-15-29-31)30-25-21-11-17(10-19(32)13-33-2)3-5-22(21)26-14-28-25;1-3-32(30)18-5-6-20-19(12-18)23(26-13-24-20)28-16-4-7-21(15(2)10-16)31-17-8-9-29-22(11-17)25-14-27-29;1-3-30-17-5-6-20-19(11-17)23(26-13-24-20)28-16-4-7-21(15(2)10-16)31-18-8-9-29-22(12-18)25-14-27-29/h2-6,9,12-13,15-17,20H,7-8,10-11,14H2,1H3,(H,29,31,33);4-8,10,13-17H,2-3,9,11-12H2,1H3,(H,28,30,32);3-8,11-15H,9-10H2,1-2H3,(H,26,28,30);3-9,11-12,14-15H,10,13H2,1-2H3,(H,26,28,30);4-14H,3H2,1-2H3,(H,24,26,28);4-14H,3H2,1-2H3,(H,24,26,28).

What are the key properties of 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one?

6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one has a molecular weight of 2768.07 g/mol, XLogP of 27.80, 40 rotatable bonds, 6 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 6-ethoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;6-ethylsulfinyl-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;1-methoxy-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]propan-2-one;1-methyl-3-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]imidazolidin-2-one;2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-1-(oxan-4-yl)ethanone;1-[2-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxyethyl]pyrrolidin-2-one is sourced from PubChem (CID 159151204), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).