(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide

C379H388Cl5F8N39O60S — CID 159196864

About (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide

(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide (PubChem CID 159196864) has the molecular formula C379H388Cl5F8N39O60S and a molecular weight of 6810.80 g/mol. Its IUPAC name is (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide.

Molecular Properties

• Compound Name: (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide
• PubChem CID: 159196864
• Molecular Formula: C379H388Cl5F8N39O60S
• Molecular Weight: 6810.80 g/mol
• Exact Mass: 6803.65
• IUPAC Name: (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide
• SMILES: CCC1(c2ccccc2)CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(-c2ccncc2)cc1.COc1cccc(-c2ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCC[C@@H]3c3cccc(Cl)c3)cc2)n1.COc1cccc(-c2ccc([C@@H](C)NC(=O)[C@H](O)[C@@H](O)C(=O)N3CCC[C@@H]3c3cccc(Cl)c3)cc2)n1.COc1ncccc1-c1ccc([C@@H](C)NC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)c1ccc(-c2ccc[nH]c2=O)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccccc2C(F)(F)F)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2cccs2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccncc2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccccc2C(F)(F)F)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccnc3ccc(F)cc23)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2Cl)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2F)cc1.C[C@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccncc2)cc1
• InChI: InChI=1S/C29H29F3N2O4.C29H26FN3O4.C29H33N3O4.2C28H30ClN3O5.2C27H28ClN3O5.C27H25F3N2O4.2C27H29N3O4.C26H28N2O4S.C25H24ClN3O4.C25H24FN3O4.C25H25N3O4/c1-18(19-13-15-20(16-14-19)22-10-5-6-11-23(22)29(30,31)32)33-27(37)25(35)26(36)28(38)34-17-7-12-24(34)21-8-3-2-4-9-21;1-17(18-6-8-19(9-7-18)23-12-13-31-25-11-10-22(30)14-24(23)25)32-28(36)26(34)27(35)29(37)33-15-20-4-2-3-5-21(20)16-33;1-3-29(24-8-5-4-6-9-24)16-7-19-32(29)28(36)26(34)25(33)27(35)31-20(2)21-10-12-22(13-11-21)23-14-17-30-18-15-23;1-17(18-10-12-19(13-11-18)22-8-4-14-30-27(22)37-2)31-26(35)24(33)25(34)28(36)32-15-5-9-23(32)20-6-3-7-21(29)16-20;1-17(18-11-13-19(14-12-18)22-8-4-10-24(31-22)37-2)30-27(35)25(33)26(34)28(36)32-15-5-9-23(32)20-6-3-7-21(29)16-20;1-16(17-9-11-18(12-10-17)21-7-3-13-29-25(21)34)30-26(35)23(32)24(33)27(36)31-14-4-8-22(31)19-5-2-6-20(28)15-19;1-36-23-9-3-7-21(30-23)18-12-10-17(11-13-18)16-29-26(34)24(32)25(33)27(35)31-14-4-8-22(31)19-5-2-6-20(28)15-19;1-16(17-10-12-18(13-11-17)21-8-4-5-9-22(21)27(28,29)30)31-25(35)23(33)24(34)26(36)32-14-19-6-2-3-7-20(19)15-32;2*1-18(19-9-11-20(12-10-19)21-13-15-28-16-14-21)29-26(33)24(31)25(32)27(34)30-17-5-8-23(30)22-6-3-2-4-7-22;1-17(18-11-13-20(14-12-18)22-10-6-16-33-22)27-25(31)23(29)24(30)26(32)28-15-5-9-21(28)19-7-3-2-4-8-19;2*1-15(16-6-8-17(9-7-16)20-10-11-27-12-21(20)26)28-24(32)22(30)23(31)25(33)29-13-18-4-2-3-5-19(18)14-29;1-16(17-6-8-18(9-7-17)19-10-12-26-13-11-19)27-24(31)22(29)23(30)25(32)28-14-20-4-2-3-5-21(20)15-28/h2-6,8-11,13-16,18,24-26,35-36H,7,12,17H2,1H3,(H,33,37);2-14,17,26-27,34-35H,15-16H2,1H3,(H,32,36);4-6,8-15,17-18,20,25-26,33-34H,3,7,16,19H2,1-2H3,(H,31,35);3-4,6-8,10-14,16-17,23-25,33-34H,5,9,15H2,1-2H3,(H,31,35);3-4,6-8,10-14,16-17,23,25-26,33-34H,5,9,15H2,1-2H3,(H,30,35);2-3,5-7,9-13,15-16,22-24,32-33H,4,8,14H2,1H3,(H,29,34)(H,30,35);2-3,5-7,9-13,15,22,24-25,32-33H,4,8,14,16H2,1H3,(H,29,34);2-13,16,23-24,33-34H,14-15H2,1H3,(H,31,35);2*2-4,6-7,9-16,18,23-25,31-32H,5,8,17H2,1H3,(H,29,33);2-4,6-8,10-14,16-17,21,23-24,29-30H,5,9,15H2,1H3,(H,27,31);2*2-12,15,22-23,30-31H,13-14H2,1H3,(H,28,32);2-13,16,22-23,29-30H,14-15H2,1H3,(H,27,31)/t18-,24-,25-,26-;17-,26-,27-;20-,25-,26-,29?;17-,23?,24-,25-;17-,23-,25-,26-;16-,22-,23-,24-;22-,24-,25-;16-,23-,24-;18-,23+,24+,25+;18-,23-,24-,25-;17-,21-,23-,24-;2*15-,22-,23-;16-,22-,23-/m11111111011111/s1
• InChIKey: KOTQBIFDSMXCRX-VXHYAJTASA-N
• XLogP: 45.99
• TPSA: 1447.63 Ų
• H-Bond Donors: 43
• H-Bond Acceptors: 71
• Rotatable Bonds: 97
• Heavy Atoms: 492
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	6810.80
LogP ≤ 5	45.99
H-Bond Donors ≤ 5	43
H-Bond Acceptors ≤ 10	71

Frequently Asked Questions

What is the IUPAC name of (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide?

The IUPAC name of (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide (CID 159196864) is (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide.

What is the SMILES notation for (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide?

The canonical SMILES for (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide is CCC1(c2ccccc2)CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(-c2ccncc2)cc1.COc1cccc(-c2ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N3CCC[C@@H]3c3cccc(Cl)c3)cc2)n1.COc1cccc(-c2ccc([C@@H](C)NC(=O)[C@H](O)[C@@H](O)C(=O)N3CCC[C@@H]3c3cccc(Cl)c3)cc2)n1.COc1ncccc1-c1ccc([C@@H](C)NC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)c1ccc(-c2ccc[nH]c2=O)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccccc2C(F)(F)F)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2cccs2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccncc2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccccc2C(F)(F)F)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccnc3ccc(F)cc23)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2Cl)cc1.C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1Cc2ccccc2C1)c1ccc(-c2ccncc2F)cc1.C[C@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccc(-c2ccncc2)cc1.

What is the InChIKey of (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide?

The InChIKey is KOTQBIFDSMXCRX-VXHYAJTASA-N. The full InChI is InChI=1S/C29H29F3N2O4.C29H26FN3O4.C29H33N3O4.2C28H30ClN3O5.2C27H28ClN3O5.C27H25F3N2O4.2C27H29N3O4.C26H28N2O4S.C25H24ClN3O4.C25H24FN3O4.C25H25N3O4/c1-18(19-13-15-20(16-14-19)22-10-5-6-11-23(22)29(30,31)32)33-27(37)25(35)26(36)28(38)34-17-7-12-24(34)21-8-3-2-4-9-21;1-17(18-6-8-19(9-7-18)23-12-13-31-25-11-10-22(30)14-24(23)25)32-28(36)26(34)27(35)29(37)33-15-20-4-2-3-5-21(20)16-33;1-3-29(24-8-5-4-6-9-24)16-7-19-32(29)28(36)26(34)25(33)27(35)31-20(2)21-10-12-22(13-11-21)23-14-17-30-18-15-23;1-17(18-10-12-19(13-11-18)22-8-4-14-30-27(22)37-2)31-26(35)24(33)25(34)28(36)32-15-5-9-23(32)20-6-3-7-21(29)16-20;1-17(18-11-13-19(14-12-18)22-8-4-10-24(31-22)37-2)30-27(35)25(33)26(34)28(36)32-15-5-9-23(32)20-6-3-7-21(29)16-20;1-16(17-9-11-18(12-10-17)21-7-3-13-29-25(21)34)30-26(35)23(32)24(33)27(36)31-14-4-8-22(31)19-5-2-6-20(28)15-19;1-36-23-9-3-7-21(30-23)18-12-10-17(11-13-18)16-29-26(34)24(32)25(33)27(35)31-14-4-8-22(31)19-5-2-6-20(28)15-19;1-16(17-10-12-18(13-11-17)21-8-4-5-9-22(21)27(28,29)30)31-25(35)23(33)24(34)26(36)32-14-19-6-2-3-7-20(19)15-32;2*1-18(19-9-11-20(12-10-19)21-13-15-28-16-14-21)29-26(33)24(31)25(32)27(34)30-17-5-8-23(30)22-6-3-2-4-7-22;1-17(18-11-13-20(14-12-18)22-10-6-16-33-22)27-25(31)23(29)24(30)26(32)28-15-5-9-21(28)19-7-3-2-4-8-19;2*1-15(16-6-8-17(9-7-16)20-10-11-27-12-21(20)26)28-24(32)22(30)23(31)25(33)29-13-18-4-2-3-5-19(18)14-29;1-16(17-6-8-18(9-7-17)19-10-12-26-13-11-19)27-24(31)22(29)23(30)25(32)28-14-20-4-2-3-5-21(20)15-28/h2-6,8-11,13-16,18,24-26,35-36H,7,12,17H2,1H3,(H,33,37);2-14,17,26-27,34-35H,15-16H2,1H3,(H,32,36);4-6,8-15,17-18,20,25-26,33-34H,3,7,16,19H2,1-2H3,(H,31,35);3-4,6-8,10-14,16-17,23-25,33-34H,5,9,15H2,1-2H3,(H,31,35);3-4,6-8,10-14,16-17,23,25-26,33-34H,5,9,15H2,1-2H3,(H,30,35);2-3,5-7,9-13,15-16,22-24,32-33H,4,8,14H2,1H3,(H,29,34)(H,30,35);2-3,5-7,9-13,15,22,24-25,32-33H,4,8,14,16H2,1H3,(H,29,34);2-13,16,23-24,33-34H,14-15H2,1H3,(H,31,35);2*2-4,6-7,9-16,18,23-25,31-32H,5,8,17H2,1H3,(H,29,33);2-4,6-8,10-14,16-17,21,23-24,29-30H,5,9,15H2,1H3,(H,27,31);2*2-12,15,22-23,30-31H,13-14H2,1H3,(H,28,32);2-13,16,22-23,29-30H,14-15H2,1H3,(H,27,31)/t18-,24-,25-,26-;17-,26-,27-;20-,25-,26-,29?;17-,23?,24-,25-;17-,23-,25-,26-;16-,22-,23-,24-;22-,24-,25-;16-,23-,24-;18-,23+,24+,25+;18-,23-,24-,25-;17-,21-,23-,24-;2*15-,22-,23-;16-,22-,23-/m11111111011111/s1.

What are the key properties of (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide?

(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide has a molecular weight of 6810.80 g/mol, XLogP of 45.99, 97 rotatable bonds, 43 hydrogen bond donors, and 71 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[(1R)-1-[4-(2-methoxy-3-pyridinyl)phenyl]ethyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-N-[[4-(6-methoxy-2-pyridinyl)phenyl]methyl]-4-oxobutanamide;(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-(2-oxo-1H-pyridin-3-yl)phenyl]ethyl]butanamide;(2R,3R)-N-[(1R)-1-[4-(3-chloro-4-pyridinyl)phenyl]ethyl]-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(3-fluoro-4-pyridinyl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-4-(1,3-dihydroisoindol-2-yl)-N-[(1R)-1-[4-(6-fluoroquinolin-4-yl)phenyl]ethyl]-2,3-dihydroxy-4-oxobutanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1S)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-(4-thiophen-2-ylphenyl)ethyl]butanamide;(2R,3R)-2,3-dihydroxy-4-oxo-4-[(2R)-2-phenylpyrrolidin-1-yl]-N-[(1R)-1-[4-[2-(trifluoromethyl)phenyl]phenyl]ethyl]butanamide;(2R,3R)-4-(2-ethyl-2-phenylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-[(1R)-1-(4-pyridin-4-ylphenyl)ethyl]butanamide is sourced from PubChem (CID 159196864), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).