N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate

C251H235ClF15N39O29S7 — CID 159203597

IUPACN-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate
SMILESCC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.CC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(OCC(F)(F)F)cc3n2C2CCC2)cc1)C1CC1.N#Cc1c(-c2ccc(NC(=O)NC3CCC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)c(Cl)c2)n(C2CCC2)c2cc(Oc3ncccn3)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2ccc(OC(F)F)cc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CCC3)cc2)n(C2CC2)c2cc(Oc3ncccn3)ccc12
InChIInChI=1S/C27H26F3N3O3.C26H22ClN5O3S.C26H25F3N4O2.C26H23N5O3S.C26H25N5O3S.C26H23N5O3.C24H22F3N3O3S.C24H25F2N3O3S.C23H21F2N3O3S.C23H23F2N3O3S/c1-16(17-5-6-17)36-26(34)32-19-9-7-18(8-10-19)25-23(14-31)22-12-11-21(35-15-27(28,29)30)13-24(22)33(25)20-3-2-4-20;27-22-13-16(5-10-23(22)31-36(33,34)19-7-8-19)25-21(15-28)20-9-6-18(35-26-29-11-2-12-30-26)14-24(20)32(25)17-3-1-4-17;27-26(28,29)15-35-20-11-12-21-22(14-30)24(33(23(21)13-20)19-5-2-6-19)16-7-9-18(10-8-16)32-25(34)31-17-3-1-4-17;27-16-23-22-12-11-20(34-26-28-13-2-14-29-26)15-24(22)31(19-9-10-19)25(23)17-5-7-18(8-6-17)30-35(32,33)21-3-1-4-21;1-17(2)16-35(32,33)30-19-6-4-18(5-7-19)25-23(15-27)22-11-10-21(34-26-28-12-3-13-29-26)14-24(22)31(25)20-8-9-20;1-16(2)33-26(32)30-18-6-4-17(5-7-18)24-22(15-27)21-11-10-20(34-25-28-12-3-13-29-25)14-23(21)31(24)19-8-9-19;25-24(26,27)14-33-18-8-11-20-21(13-28)23(30(22(20)12-18)17-2-1-3-17)15-4-6-16(7-5-15)29-34(31,32)19-9-10-19;1-15(2)14-33(30,31)28-17-8-6-16(7-9-17)23-21(13-27)20-12-19(32-24(25)26)10-11-22(20)29(23)18-4-3-5-18;24-23(25)31-17-8-11-21-19(12-17)20(13-26)22(28(21)16-2-1-3-16)14-4-6-15(7-5-14)27-32(29,30)18-9-10-18;1-14(2)32(29,30)27-16-8-6-15(7-9-16)22-20(13-26)19-12-18(31-23(24)25)10-11-21(19)28(22)17-4-3-5-17/h7-13,16-17,20H,2-6,15H2,1H3,(H,32,34);2,5-6,9-14,17,19,31H,1,3-4,7-8H2;7-13,17,19H,1-6,15H2,(H2,31,32,34);2,5-8,11-15,19,21,30H,1,3-4,9-10H2;3-7,10-14,17,20,30H,8-9,16H2,1-2H3;3-7,10-14,16,19H,8-9H2,1-2H3,(H,30,32);4-8,11-12,17,19,29H,1-3,9-10,14H2;6-12,15,18,24,28H,3-5,14H2,1-2H3;4-8,11-12,16,18,23,27H,1-3,9-10H2;6-12,14,17,23,27H,3-5H2,1-2H3/t16-;;;;;;;;;/m1........./s1
InChIKeyKPPDJDQYLYCXRG-NTFOZJTKSA-N
MW4806.78 g/mol
LogP59.42
Rot. Bonds70

About N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate

N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate (PubChem CID 159203597) has the molecular formula C251H235ClF15N39O29S7 and a molecular weight of 4806.78 g/mol. Its IUPAC name is N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate.

Molecular Properties

Compound NameN-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate
PubChem CID159203597
Molecular FormulaC251H235ClF15N39O29S7
Molecular Weight4806.78 g/mol
Exact Mass4802.56
IUPAC NameN-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate
SMILESCC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.CC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(OCC(F)(F)F)cc3n2C2CCC2)cc1)C1CC1.N#Cc1c(-c2ccc(NC(=O)NC3CCC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)c(Cl)c2)n(C2CCC2)c2cc(Oc3ncccn3)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2ccc(OC(F)F)cc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CCC3)cc2)n(C2CC2)c2cc(Oc3ncccn3)ccc12
InChIInChI=1S/C27H26F3N3O3.C26H22ClN5O3S.C26H25F3N4O2.C26H23N5O3S.C26H25N5O3S.C26H23N5O3.C24H22F3N3O3S.C24H25F2N3O3S.C23H21F2N3O3S.C23H23F2N3O3S/c1-16(17-5-6-17)36-26(34)32-19-9-7-18(8-10-19)25-23(14-31)22-12-11-21(35-15-27(28,29)30)13-24(22)33(25)20-3-2-4-20;27-22-13-16(5-10-23(22)31-36(33,34)19-7-8-19)25-21(15-28)20-9-6-18(35-26-29-11-2-12-30-26)14-24(20)32(25)17-3-1-4-17;27-26(28,29)15-35-20-11-12-21-22(14-30)24(33(23(21)13-20)19-5-2-6-19)16-7-9-18(10-8-16)32-25(34)31-17-3-1-4-17;27-16-23-22-12-11-20(34-26-28-13-2-14-29-26)15-24(22)31(19-9-10-19)25(23)17-5-7-18(8-6-17)30-35(32,33)21-3-1-4-21;1-17(2)16-35(32,33)30-19-6-4-18(5-7-19)25-23(15-27)22-11-10-21(34-26-28-12-3-13-29-26)14-24(22)31(25)20-8-9-20;1-16(2)33-26(32)30-18-6-4-17(5-7-18)24-22(15-27)21-11-10-20(34-25-28-12-3-13-29-25)14-23(21)31(24)19-8-9-19;25-24(26,27)14-33-18-8-11-20-21(13-28)23(30(22(20)12-18)17-2-1-3-17)15-4-6-16(7-5-15)29-34(31,32)19-9-10-19;1-15(2)14-33(30,31)28-17-8-6-16(7-9-17)23-21(13-27)20-12-19(32-24(25)26)10-11-22(20)29(23)18-4-3-5-18;24-23(25)31-17-8-11-21-19(12-17)20(13-26)22(28(21)16-2-1-3-16)14-4-6-15(7-5-14)27-32(29,30)18-9-10-18;1-14(2)32(29,30)27-16-8-6-15(7-9-16)22-20(13-26)19-12-18(31-23(24)25)10-11-21(19)28(22)17-4-3-5-17/h7-13,16-17,20H,2-6,15H2,1H3,(H,32,34);2,5-6,9-14,17,19,31H,1,3-4,7-8H2;7-13,17,19H,1-6,15H2,(H2,31,32,34);2,5-8,11-15,19,21,30H,1,3-4,9-10H2;3-7,10-14,17,20,30H,8-9,16H2,1-2H3;3-7,10-14,16,19H,8-9H2,1-2H3,(H,30,32);4-8,11-12,17,19,29H,1-3,9-10,14H2;6-12,15,18,24,28H,3-5,14H2,1-2H3;4-8,11-12,16,18,23,27H,1-3,9-10H2;6-12,14,17,23,27H,3-5H2,1-2H3/t16-;;;;;;;;;/m1........./s1
InChIKeyKPPDJDQYLYCXRG-NTFOZJTKSA-N
XLogP59.42
TPSA923.60 Ų
H-Bond Donors11
H-Bond Acceptors57
Rotatable Bonds70
Heavy Atoms342
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004806.78
LogP ≤ 559.42
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1057

Analyze N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate with MolForge

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Related Compounds

CID 157082105
CID 157082105
CID 157153677
CID 157153677
1-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-3-propan-2-ylurea;1-cyclobutyl-2-[2-(propan-2-ylamino)pyrimidin-5-yl]-6-pyrimidin-2-yloxyindole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;2-[4-[1-(cyclopropylmethyl)-6-pyrimidin-2-yloxyindol-2-yl]phenyl]-1,2-thiazolidine 1,1-dioxide;propan-2-yl N-[2-cyano-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[5-[1-(azetidin-1-yl)-3-cyano-6-pyrimidin-2-yloxy-1H-inden-2-yl]-2-pyridinyl]carbamate
CID 157159756
N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]propane-1-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]-3-propan-2-ylurea;1-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]-3-propan-2-ylurea;N-[4-[3-cyano-1-cyclopropyl-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-[(2S)-2,3-dihydroxypropoxy]indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-[3-cyano-1-cyclobutyl-6-(2-fluoroethoxy)indol-2-yl]-2,6-difluorophenyl]carbamate;[(2R)-1,1,1-trifluoropropan-2-yl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(2,2-difluoroethoxy)indol-2-yl]phenyl]carbamate
CID 157180987
N-[4-[6-[(3-bromo-2-pyridinyl)oxy]-3-cyano-1-cyclopropylindol-2-yl]phenyl]propane-1-sulfonamide;1-cyclobutyl-6-[(3-fluoro-2-pyridinyl)oxy]-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-6-(4-methylpyrimidin-2-yl)oxy-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-cyclobutyl-2-[4-(propan-2-ylamino)phenyl]-6-[[3-(trifluoromethyl)-2-pyridinyl]oxy]indole-3-carbonitrile;[(1R)-1-cyclopropylethyl] N-[4-[6-(5-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[6-(6-chloro-2-pyridinyl)-3-cyano-1-cyclobutylindol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(5-methyl-2-pyridinyl)indol-2-yl]phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclopropyl-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]phenyl]carbamate
CID 157210131
CID 157301426
CID 157301426
N-[4-[3-cyano-1-(cyclopropylmethyl)-6-[(3-fluoro-2-pyridinyl)oxy]indol-2-yl]-3-methylphenyl]propane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-(cyclopropylmethyl)-6-(4-methylpyrimidin-2-yl)oxyindol-2-yl]-3-methylphenyl]carbamate;1-(cyclopropylmethyl)-6-(2-methylsulfonylethoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;1-(cyclopropylmethyl)-6-(3-methylsulfonylpropoxy)-2-[4-(propan-2-ylamino)phenyl]indole-3-carbonitrile;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2,6-difluorophenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)-2-(trifluoromethoxy)phenyl]carbamate
CID 157344993
CID 157438060
CID 157438060
CID 157632056
CID 157632056
CID 157834402
CID 157834402
CID 157936386
CID 157936386
CID 157949272
CID 157949272

Frequently Asked Questions

What is the IUPAC name of N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate?
The IUPAC name of N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate (CID 159203597) is N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate.
What is the SMILES notation for N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate?
The canonical SMILES for N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate is CC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.CC(C)CS(=O)(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CC2)cc1.CC(C)S(=O)(=O)Nc1ccc(-c2c(C#N)c3cc(OC(F)F)ccc3n2C2CCC2)cc1.C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(OCC(F)(F)F)cc3n2C2CCC2)cc1)C1CC1.N#Cc1c(-c2ccc(NC(=O)NC3CCC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)c(Cl)c2)n(C2CCC2)c2cc(Oc3ncccn3)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2cc(OCC(F)(F)F)ccc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)n(C2CCC2)c2ccc(OC(F)F)cc12.N#Cc1c(-c2ccc(NS(=O)(=O)C3CCC3)cc2)n(C2CC2)c2cc(Oc3ncccn3)ccc12.
What is the InChIKey of N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate?
The InChIKey is KPPDJDQYLYCXRG-NTFOZJTKSA-N. The full InChI is InChI=1S/C27H26F3N3O3.C26H22ClN5O3S.C26H25F3N4O2.C26H23N5O3S.C26H25N5O3S.C26H23N5O3.C24H22F3N3O3S.C24H25F2N3O3S.C23H21F2N3O3S.C23H23F2N3O3S/c1-16(17-5-6-17)36-26(34)32-19-9-7-18(8-10-19)25-23(14-31)22-12-11-21(35-15-27(28,29)30)13-24(22)33(25)20-3-2-4-20;27-22-13-16(5-10-23(22)31-36(33,34)19-7-8-19)25-21(15-28)20-9-6-18(35-26-29-11-2-12-30-26)14-24(20)32(25)17-3-1-4-17;27-26(28,29)15-35-20-11-12-21-22(14-30)24(33(23(21)13-20)19-5-2-6-19)16-7-9-18(10-8-16)32-25(34)31-17-3-1-4-17;27-16-23-22-12-11-20(34-26-28-13-2-14-29-26)15-24(22)31(19-9-10-19)25(23)17-5-7-18(8-6-17)30-35(32,33)21-3-1-4-21;1-17(2)16-35(32,33)30-19-6-4-18(5-7-19)25-23(15-27)22-11-10-21(34-26-28-12-3-13-29-26)14-24(22)31(25)20-8-9-20;1-16(2)33-26(32)30-18-6-4-17(5-7-18)24-22(15-27)21-11-10-20(34-25-28-12-3-13-29-25)14-23(21)31(24)19-8-9-19;25-24(26,27)14-33-18-8-11-20-21(13-28)23(30(22(20)12-18)17-2-1-3-17)15-4-6-16(7-5-15)29-34(31,32)19-9-10-19;1-15(2)14-33(30,31)28-17-8-6-16(7-9-17)23-21(13-27)20-12-19(32-24(25)26)10-11-22(20)29(23)18-4-3-5-18;24-23(25)31-17-8-11-21-19(12-17)20(13-26)22(28(21)16-2-1-3-16)14-4-6-15(7-5-14)27-32(29,30)18-9-10-18;1-14(2)32(29,30)27-16-8-6-15(7-9-16)22-20(13-26)19-12-18(31-23(24)25)10-11-21(19)28(22)17-4-3-5-17/h7-13,16-17,20H,2-6,15H2,1H3,(H,32,34);2,5-6,9-14,17,19,31H,1,3-4,7-8H2;7-13,17,19H,1-6,15H2,(H2,31,32,34);2,5-8,11-15,19,21,30H,1,3-4,9-10H2;3-7,10-14,17,20,30H,8-9,16H2,1-2H3;3-7,10-14,16,19H,8-9H2,1-2H3,(H,30,32);4-8,11-12,17,19,29H,1-3,9-10,14H2;6-12,15,18,24,28H,3-5,14H2,1-2H3;4-8,11-12,16,18,23,27H,1-3,9-10H2;6-12,14,17,23,27H,3-5H2,1-2H3/t16-;;;;;;;;;/m1........./s1.
What are the key properties of N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate?
N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate has a molecular weight of 4806.78 g/mol, XLogP of 59.42, 70 rotatable bonds, 11 hydrogen bond donors, and 57 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-chloro-4-(3-cyano-1-cyclobutyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]-2-methylpropane-1-sulfonamide;N-[4-[3-cyano-1-cyclobutyl-5-(difluoromethoxy)indol-2-yl]phenyl]propane-2-sulfonamide;1-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]-3-cyclobutylurea;N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]cyclopropanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]cyclobutanesulfonamide;N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]-2-methylpropane-1-sulfonamide;[(1R)-1-cyclopropylethyl] N-[4-[3-cyano-1-cyclobutyl-6-(2,2,2-trifluoroethoxy)indol-2-yl]phenyl]carbamate;propan-2-yl N-[4-(3-cyano-1-cyclopropyl-6-pyrimidin-2-yloxyindol-2-yl)phenyl]carbamate is sourced from PubChem (CID 159203597), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).