6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol

C102H86F17N27O5 — CID 159272754

About 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol

6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol (PubChem CID 159272754) has the molecular formula C102H86F17N27O5 and a molecular weight of 2092.96 g/mol. Its IUPAC name is 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol.

Molecular Properties

• Compound Name: 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol
• PubChem CID: 159272754
• Molecular Formula: C102H86F17N27O5
• Molecular Weight: 2092.96 g/mol
• Exact Mass: 2091.70
• IUPAC Name: 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol
• SMILES: CCc1nc2c(n1-c1cncc(Nc3ccc(C(F)(F)F)cc3)n1)CN(C)CC2.COCCn1nc(C)c(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)c1C.Cc1nc2ccc(NCCO)cc2n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ccc(O)cn2c1-c1cc(C#N)cc(Nc2ccc(OC(F)(F)F)cc2)n1.N#Cc1cc(Nc2ccc(C(F)(F)F)c(F)c2)nc(-c2c(CO)nc3ccc(F)cn23)c1
• InChI: InChI=1S/C21H12F5N5O.C21H19F3N6O.C21H14F3N5O2.C20H21F3N6.C19H20F3N5O/c22-12-1-4-19-30-17(10-32)20(31(19)9-12)16-5-11(8-27)6-18(29-16)28-13-2-3-14(15(23)7-13)21(24,25)26;1-13-27-17-7-6-16(26-8-9-31)10-18(17)30(13)20-12-25-11-19(29-20)28-15-4-2-14(3-5-15)21(22,23)24;1-12-20(29-11-15(30)4-7-19(29)26-12)17-8-13(10-25)9-18(28-17)27-14-2-5-16(6-3-14)31-21(22,23)24;1-3-18-26-15-8-9-28(2)12-16(15)29(18)19-11-24-10-17(27-19)25-14-6-4-13(5-7-14)20(21,22)23;1-12-18(13(2)27(26-12)8-9-28-3)16-10-23-11-17(25-16)24-15-6-4-14(5-7-15)19(20,21)22/h1-7,9,32H,10H2,(H,28,29);2-7,10-12,26,31H,8-9H2,1H3,(H,28,29);2-9,11,30H,1H3,(H,27,28);4-7,10-11H,3,8-9,12H2,1-2H3,(H,25,27);4-7,10-11H,8-9H2,1-3H3,(H,24,25)
• InChIKey: KXXMCVIGXLJIIG-UHFFFAOYSA-N
• XLogP: 22.36
• TPSA: 393.33 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 32
• Rotatable Bonds: 24
• Heavy Atoms: 151
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2092.96
LogP ≤ 5	22.36
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol?

The IUPAC name of 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol (CID 159272754) is 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol.

What is the SMILES notation for 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol?

The canonical SMILES for 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol is CCc1nc2c(n1-c1cncc(Nc3ccc(C(F)(F)F)cc3)n1)CN(C)CC2.COCCn1nc(C)c(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)c1C.Cc1nc2ccc(NCCO)cc2n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ccc(O)cn2c1-c1cc(C#N)cc(Nc2ccc(OC(F)(F)F)cc2)n1.N#Cc1cc(Nc2ccc(C(F)(F)F)c(F)c2)nc(-c2c(CO)nc3ccc(F)cn23)c1.

What is the InChIKey of 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol?

The InChIKey is KXXMCVIGXLJIIG-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H12F5N5O.C21H19F3N6O.C21H14F3N5O2.C20H21F3N6.C19H20F3N5O/c22-12-1-4-19-30-17(10-32)20(31(19)9-12)16-5-11(8-27)6-18(29-16)28-13-2-3-14(15(23)7-13)21(24,25)26;1-13-27-17-7-6-16(26-8-9-31)10-18(17)30(13)20-12-25-11-19(29-20)28-15-4-2-14(3-5-15)21(22,23)24;1-12-20(29-11-15(30)4-7-19(29)26-12)17-8-13(10-25)9-18(28-17)27-14-2-5-16(6-3-14)31-21(22,23)24;1-3-18-26-15-8-9-28(2)12-16(15)29(18)19-11-24-10-17(27-19)25-14-6-4-13(5-7-14)20(21,22)23;1-12-18(13(2)27(26-12)8-9-28-3)16-10-23-11-17(25-16)24-15-6-4-14(5-7-15)19(20,21)22/h1-7,9,32H,10H2,(H,28,29);2-7,10-12,26,31H,8-9H2,1H3,(H,28,29);2-9,11,30H,1H3,(H,27,28);4-7,10-11H,3,8-9,12H2,1-2H3,(H,25,27);4-7,10-11H,8-9H2,1-3H3,(H,24,25).

What are the key properties of 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol?

6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol has a molecular weight of 2092.96 g/mol, XLogP of 22.36, 24 rotatable bonds, 9 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(2-ethyl-5-methyl-6,7-dihydro-4H-imidazo[4,5-c]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[6-fluoro-2-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]-6-[3-fluoro-4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-hydroxy-2-methylimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethoxy)anilino]pyridine-4-carbonitrile;6-[1-(2-methoxyethyl)-3,5-dimethylpyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-[[2-methyl-3-[6-[4-(trifluoromethyl)anilino]pyrazin-2-yl]benzimidazol-5-yl]amino]ethanol is sourced from PubChem (CID 159272754), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).