4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide

C141H150F15N43O8S5 — CID 159272756

IUPAC4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
SMILESC[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC(N4CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC4(CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC4(CC3)COC4)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(C4CC4)CC3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(CC4CC4)CC3)cn2)cs1)C(F)(F)F
InChIInChI=1S/C29H32F3N9OS.C28H30F3N9O2S.C28H30F3N9OS.2C28H29F3N8O2S/c1-18(29(30,31)32)41-7-6-33-26(41)28-37-25(16-43-28)36-27(42)21-12-23(40-15-22(35-17-40)20-4-5-20)24(13-34-21)39-10-8-38(9-11-39)14-19-2-3-19;1-17(28(29,30)31)40-5-4-32-25(40)27-36-24(15-43-27)35-26(41)20-10-22(39-14-21(34-16-39)18-2-3-18)23(11-33-20)38-12-19(13-38)37-6-8-42-9-7-37;1-17(28(29,30)31)40-7-6-32-25(40)27-36-24(15-42-27)35-26(41)20-12-22(39-14-21(34-16-39)18-2-3-18)23(13-33-20)38-10-8-37(9-11-38)19-4-5-19;1-17(28(29,30)31)39-7-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(37-12-20(34-16-37)18-2-3-18)22(11-33-19)38-14-27(15-38)4-8-41-9-5-27;1-17(28(29,30)31)39-9-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(38-12-20(34-16-38)18-2-3-18)22(11-33-19)37-7-4-27(5-8-37)14-41-15-27/h6-7,12-13,15-20H,2-5,8-11,14H2,1H3,(H,36,42);4-5,10-11,14-19H,2-3,6-9,12-13H2,1H3,(H,35,41);6-7,12-19H,2-5,8-11H2,1H3,(H,35,41);6-7,10-13,16-18H,2-5,8-9,14-15H2,1H3,(H,35,40);6,9-13,16-18H,2-5,7-8,14-15H2,1H3,(H,35,40)/t18-;4*17-/m00000/s1
InChIKeyKXXMDDSMVSBZAP-SOXZQHRUSA-N
MW3020.35 g/mol
LogP25.77
Rot. Bonds39

About 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide

4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide (PubChem CID 159272756) has the molecular formula C141H150F15N43O8S5 and a molecular weight of 3020.35 g/mol. Its IUPAC name is 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide.

Molecular Properties

Compound Name4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
PubChem CID159272756
Molecular FormulaC141H150F15N43O8S5
Molecular Weight3020.35 g/mol
Exact Mass3018.10
IUPAC Name4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
SMILESC[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC(N4CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC4(CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC4(CC3)COC4)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(C4CC4)CC3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(CC4CC4)CC3)cn2)cs1)C(F)(F)F
InChIInChI=1S/C29H32F3N9OS.C28H30F3N9O2S.C28H30F3N9OS.2C28H29F3N8O2S/c1-18(29(30,31)32)41-7-6-33-26(41)28-37-25(16-43-28)36-27(42)21-12-23(40-15-22(35-17-40)20-4-5-20)24(13-34-21)39-10-8-38(9-11-39)14-19-2-3-19;1-17(28(29,30)31)40-5-4-32-25(40)27-36-24(15-43-27)35-26(41)20-10-22(39-14-21(34-16-39)18-2-3-18)23(11-33-20)38-12-19(13-38)37-6-8-42-9-7-37;1-17(28(29,30)31)40-7-6-32-25(40)27-36-24(15-42-27)35-26(41)20-12-22(39-14-21(34-16-39)18-2-3-18)23(13-33-20)38-10-8-37(9-11-38)19-4-5-19;1-17(28(29,30)31)39-7-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(37-12-20(34-16-37)18-2-3-18)22(11-33-19)38-14-27(15-38)4-8-41-9-5-27;1-17(28(29,30)31)39-9-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(38-12-20(34-16-38)18-2-3-18)22(11-33-19)37-7-4-27(5-8-37)14-41-15-27/h6-7,12-13,15-20H,2-5,8-11,14H2,1H3,(H,36,42);4-5,10-11,14-19H,2-3,6-9,12-13H2,1H3,(H,35,41);6-7,12-19H,2-5,8-11H2,1H3,(H,35,41);6-7,10-13,16-18H,2-5,8-9,14-15H2,1H3,(H,35,40);6,9-13,16-18H,2-5,7-8,14-15H2,1H3,(H,35,40)/t18-;4*17-/m00000/s1
InChIKeyKXXMDDSMVSBZAP-SOXZQHRUSA-N
XLogP25.77
TPSA506.21 Ų
H-Bond Donors5
H-Bond Acceptors51
Rotatable Bonds39
Heavy Atoms212
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003020.35
LogP ≤ 525.77
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1051

Analyze 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide with MolForge

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Related Compounds

4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 134308515
4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 134308516
4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 134308517
4-(4-cyclopropylimidazol-1-yl)-N-[2-[N-ethenyl-N'-methyl-N-[(2S)-1,1,1-trifluoropropan-2-yl]carbamimidoyl]-1,3-thiazol-4-yl]-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyridine-2-carboxamide
CID 144870170
CID 157124446
CID 157124446
CID 159272683
CID 159272683
5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide
CID 159633478
5-(4-cyanopiperidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-fluoropiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-methoxy-4-methylpiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-methoxypiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-propanoylpiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(trifluoromethyl)piperidin-1-yl]pyridine-2-carboxamide
CID 161586022
CID 161686328
CID 161686328
5-(3-cyanoazetidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;5-(3-cyano-3-methylazetidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(difluoromethyl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-methoxy-3-methylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-methoxypyrrolidin-1-yl)pyridine-2-carboxamide
CID 161756960
4-(4-cyclopropylimidazol-1-yl)-N-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]-5-(3-hydroxy-3-methylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]-5-morpholin-4-ylpyridine-2-carboxamide
CID 90240758
4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide
CID 134308490

Frequently Asked Questions

What is the IUPAC name of 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide?
The IUPAC name of 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide (CID 159272756) is 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide.
What is the SMILES notation for 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide?
The canonical SMILES for 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide is C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC(N4CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CC4(CCOCC4)C3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCC4(CC3)COC4)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(C4CC4)CC3)cn2)cs1)C(F)(F)F.C[C@H](n1ccnc1-c1nc(NC(=O)c2cc(-n3cnc(C4CC4)c3)c(N3CCN(CC4CC4)CC3)cn2)cs1)C(F)(F)F.
What is the InChIKey of 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide?
The InChIKey is KXXMDDSMVSBZAP-SOXZQHRUSA-N. The full InChI is InChI=1S/C29H32F3N9OS.C28H30F3N9O2S.C28H30F3N9OS.2C28H29F3N8O2S/c1-18(29(30,31)32)41-7-6-33-26(41)28-37-25(16-43-28)36-27(42)21-12-23(40-15-22(35-17-40)20-4-5-20)24(13-34-21)39-10-8-38(9-11-39)14-19-2-3-19;1-17(28(29,30)31)40-5-4-32-25(40)27-36-24(15-43-27)35-26(41)20-10-22(39-14-21(34-16-39)18-2-3-18)23(11-33-20)38-12-19(13-38)37-6-8-42-9-7-37;1-17(28(29,30)31)40-7-6-32-25(40)27-36-24(15-42-27)35-26(41)20-12-22(39-14-21(34-16-39)18-2-3-18)23(13-33-20)38-10-8-37(9-11-38)19-4-5-19;1-17(28(29,30)31)39-7-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(37-12-20(34-16-37)18-2-3-18)22(11-33-19)38-14-27(15-38)4-8-41-9-5-27;1-17(28(29,30)31)39-9-6-32-24(39)26-36-23(13-42-26)35-25(40)19-10-21(38-12-20(34-16-38)18-2-3-18)22(11-33-19)37-7-4-27(5-8-37)14-41-15-27/h6-7,12-13,15-20H,2-5,8-11,14H2,1H3,(H,36,42);4-5,10-11,14-19H,2-3,6-9,12-13H2,1H3,(H,35,41);6-7,12-19H,2-5,8-11H2,1H3,(H,35,41);6-7,10-13,16-18H,2-5,8-9,14-15H2,1H3,(H,35,40);6,9-13,16-18H,2-5,7-8,14-15H2,1H3,(H,35,40)/t18-;4*17-/m00000/s1.
What are the key properties of 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide?
4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide has a molecular weight of 3020.35 g/mol, XLogP of 25.77, 39 rotatable bonds, 5 hydrogen bond donors, and 51 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide is sourced from PubChem (CID 159272756), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).