5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide

C165H176F3N53O10S6 — CID 159633478

IUPAC5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide
SMILESO=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCN(C4CC4)CC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCOCC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC3CC3C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCCOCC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN(CC(F)(F)F)CC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN3C(=O)OCC3C2)cn1
InChIInChI=1S/C31H36N10OS.C28H31N9O2S.C27H28F3N9OS.C27H27N9O3S.C26H28N8O2S.C26H26N8OS/c42-30(35-28-18-43-31(36-28)29-32-7-8-41(29)22-5-6-22)24-13-26(40-17-25(34-19-40)20-1-2-20)27(14-33-24)39-15-23(16-39)38-11-9-37(10-12-38)21-3-4-21;38-27(32-25-16-40-28(33-25)26-29-5-6-37(26)19-3-4-19)21-11-23(36-15-22(31-17-36)18-1-2-18)24(12-30-21)35-13-20(14-35)34-7-9-39-10-8-34;28-27(29,30)15-36-7-9-37(10-8-36)22-12-32-19(11-21(22)38-13-20(33-16-38)17-1-2-17)25(40)34-23-14-41-26(35-23)24-31-5-6-39(24)18-3-4-18;37-25(31-23-14-40-26(32-23)24-28-5-6-35(24)17-3-4-17)19-9-21(34-12-20(30-15-34)16-1-2-16)22(10-29-19)33-7-8-36-18(11-33)13-39-27(36)38;35-25(30-23-15-37-26(31-23)24-27-6-8-34(24)18-4-5-18)19-12-21(33-14-20(29-16-33)17-2-3-17)22(13-28-19)32-7-1-10-36-11-9-32;35-25(30-23-13-36-26(31-23)24-27-5-6-34(24)18-3-4-18)19-8-21(33-12-20(29-14-33)15-1-2-15)22(9-28-19)32-10-16-7-17(16)11-32/h7-8,13-14,17-23H,1-6,9-12,15-16H2,(H,35,42);5-6,11-12,15-20H,1-4,7-10,13-14H2,(H,32,38);5-6,11-14,16-18H,1-4,7-10,15H2,(H,34,40);5-6,9-10,12,14-18H,1-4,7-8,11,13H2,(H,31,37);6,8,12-18H,1-5,7,9-11H2,(H,30,35);5-6,8-9,12-18H,1-4,7,10-11H2,(H,30,35)
InChIKeyMPLAZSSCIOEILA-UHFFFAOYSA-N
MW3310.98 g/mol
LogP24.81
Rot. Bonds46

About 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide

5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide (PubChem CID 159633478) has the molecular formula C165H176F3N53O10S6 and a molecular weight of 3310.98 g/mol. Its IUPAC name is 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide.

Molecular Properties

Compound Name5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide
PubChem CID159633478
Molecular FormulaC165H176F3N53O10S6
Molecular Weight3310.98 g/mol
Exact Mass3308.32
IUPAC Name5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide
SMILESO=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCN(C4CC4)CC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCOCC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC3CC3C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCCOCC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN(CC(F)(F)F)CC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN3C(=O)OCC3C2)cn1
InChIInChI=1S/C31H36N10OS.C28H31N9O2S.C27H28F3N9OS.C27H27N9O3S.C26H28N8O2S.C26H26N8OS/c42-30(35-28-18-43-31(36-28)29-32-7-8-41(29)22-5-6-22)24-13-26(40-17-25(34-19-40)20-1-2-20)27(14-33-24)39-15-23(16-39)38-11-9-37(10-12-38)21-3-4-21;38-27(32-25-16-40-28(33-25)26-29-5-6-37(26)19-3-4-19)21-11-23(36-15-22(31-17-36)18-1-2-18)24(12-30-21)35-13-20(14-35)34-7-9-39-10-8-34;28-27(29,30)15-36-7-9-37(10-8-36)22-12-32-19(11-21(22)38-13-20(33-16-38)17-1-2-17)25(40)34-23-14-41-26(35-23)24-31-5-6-39(24)18-3-4-18;37-25(31-23-14-40-26(32-23)24-28-5-6-35(24)17-3-4-17)19-9-21(34-12-20(30-15-34)16-1-2-16)22(10-29-19)33-7-8-36-18(11-33)13-39-27(36)38;35-25(30-23-15-37-26(31-23)24-27-6-8-34(24)18-4-5-18)19-12-21(33-14-20(29-16-33)17-2-3-17)22(13-28-19)32-7-1-10-36-11-9-32;35-25(30-23-13-36-26(31-23)24-27-5-6-34(24)18-3-4-18)19-8-21(33-12-20(29-14-33)15-1-2-15)22(9-28-19)32-10-16-7-17(16)11-32/h7-8,13-14,17-23H,1-6,9-12,15-16H2,(H,35,42);5-6,11-12,15-20H,1-4,7-10,13-14H2,(H,32,38);5-6,11-14,16-18H,1-4,7-10,15H2,(H,34,40);5-6,9-10,12,14-18H,1-4,7-8,11,13H2,(H,31,37);6,8,12-18H,1-5,7,9-11H2,(H,30,35);5-6,8-9,12-18H,1-4,7,10-11H2,(H,30,35)
InChIKeyMPLAZSSCIOEILA-UHFFFAOYSA-N
XLogP24.81
TPSA623.52 Ų
H-Bond Donors6
H-Bond Acceptors62
Rotatable Bonds46
Heavy Atoms237
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003310.98
LogP ≤ 524.81
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1062

Analyze 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide with MolForge

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Related Compounds

4-(4-cyclopropylimidazol-1-yl)-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 134308510
4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 134308516
CID 157124446
CID 157124446
CID 159272683
CID 159272683
4-(4-cyclopropylimidazol-1-yl)-5-[4-(cyclopropylmethyl)piperazin-1-yl]-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(4-cyclopropylpiperazin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(3-morpholin-4-ylazetidin-1-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-N-[2-[1-[(2S)-1,1,1-trifluoropropan-2-yl]imidazol-2-yl]-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 159272756
5-(4-cyanopiperidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-fluoropiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-methoxy-4-methylpiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-methoxypiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(4-propanoylpiperidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(trifluoromethyl)piperidin-1-yl]pyridine-2-carboxamide
CID 161586022
CID 161686328
CID 161686328
5-(3-cyanoazetidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;5-(3-cyano-3-methylazetidin-1-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(difluoromethyl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-methoxy-3-methylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-methoxypyrrolidin-1-yl)pyridine-2-carboxamide
CID 161756960
4-(4-cyclopropylimidazol-1-yl)-N-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]-5-(3-hydroxy-3-methylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]-5-morpholin-4-ylpyridine-2-carboxamide
CID 90240758
5-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-4-(4-cyclopropylimidazol-1-yl)-3-[4-(4-cyclopropylimidazol-1-yl)-1-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]-3-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)-2H-pyridin-6-yl]-N-[2-(4-cyclopropyl-1,2,4-triazol-3-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide
CID 118165862
4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide
CID 134308495
4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-[4-(cyclopropylmethyl)piperazin-1-yl]azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(7-oxa-2-azaspiro[3.5]nonan-2-yl)pyridine-2-carboxamide
CID 157807738

Frequently Asked Questions

What is the IUPAC name of 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide?
The IUPAC name of 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide (CID 159633478) is 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide.
What is the SMILES notation for 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide?
The canonical SMILES for 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide is O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCN(C4CC4)CC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC(N3CCOCC3)C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC3CC3C2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCCOCC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN(CC(F)(F)F)CC2)cn1.O=C(Nc1csc(-c2nccn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCN3C(=O)OCC3C2)cn1.
What is the InChIKey of 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide?
The InChIKey is MPLAZSSCIOEILA-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H36N10OS.C28H31N9O2S.C27H28F3N9OS.C27H27N9O3S.C26H28N8O2S.C26H26N8OS/c42-30(35-28-18-43-31(36-28)29-32-7-8-41(29)22-5-6-22)24-13-26(40-17-25(34-19-40)20-1-2-20)27(14-33-24)39-15-23(16-39)38-11-9-37(10-12-38)21-3-4-21;38-27(32-25-16-40-28(33-25)26-29-5-6-37(26)19-3-4-19)21-11-23(36-15-22(31-17-36)18-1-2-18)24(12-30-21)35-13-20(14-35)34-7-9-39-10-8-34;28-27(29,30)15-36-7-9-37(10-8-36)22-12-32-19(11-21(22)38-13-20(33-16-38)17-1-2-17)25(40)34-23-14-41-26(35-23)24-31-5-6-39(24)18-3-4-18;37-25(31-23-14-40-26(32-23)24-28-5-6-35(24)17-3-4-17)19-9-21(34-12-20(30-15-34)16-1-2-16)22(10-29-19)33-7-8-36-18(11-33)13-39-27(36)38;35-25(30-23-15-37-26(31-23)24-27-6-8-34(24)18-4-5-18)19-12-21(33-14-20(29-16-33)17-2-3-17)22(13-28-19)32-7-1-10-36-11-9-32;35-25(30-23-13-36-26(31-23)24-27-5-6-34(24)18-3-4-18)19-8-21(33-12-20(29-14-33)15-1-2-15)22(9-28-19)32-10-16-7-17(16)11-32/h7-8,13-14,17-23H,1-6,9-12,15-16H2,(H,35,42);5-6,11-12,15-20H,1-4,7-10,13-14H2,(H,32,38);5-6,11-14,16-18H,1-4,7-10,15H2,(H,34,40);5-6,9-10,12,14-18H,1-4,7-8,11,13H2,(H,31,37);6,8,12-18H,1-5,7,9-11H2,(H,30,35);5-6,8-9,12-18H,1-4,7,10-11H2,(H,30,35).
What are the key properties of 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide?
5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide has a molecular weight of 3310.98 g/mol, XLogP of 24.81, 46 rotatable bonds, 6 hydrogen bond donors, and 62 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(3-azabicyclo[3.1.0]hexan-3-yl)-4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[3-(4-cyclopropylpiperazin-1-yl)azetidin-1-yl]pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-morpholin-4-ylazetidin-1-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(1,4-oxazepan-4-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-(3-oxo-5,6,8,8a-tetrahydro-1H-[1,3]oxazolo[3,4-a]pyrazin-7-yl)pyridine-2-carboxamide;4-(4-cyclopropylimidazol-1-yl)-N-[2-(1-cyclopropylimidazol-2-yl)-1,3-thiazol-4-yl]-5-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-2-carboxamide is sourced from PubChem (CID 159633478), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).