N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide

C124H89F6N21O7S3 — CID 159374539

About N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide

N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide (PubChem CID 159374539) has the molecular formula C124H89F6N21O7S3 and a molecular weight of 2195.40 g/mol. Its IUPAC name is N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide.

Molecular Properties

• Compound Name: N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
• PubChem CID: 159374539
• Molecular Formula: C124H89F6N21O7S3
• Molecular Weight: 2195.40 g/mol
• Exact Mass: 2193.63
• IUPAC Name: N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
• SMILES: CC(F)(F)Oc1cccc(-c2ccc3cccc(NC(=O)c4cnccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4cnccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4cscn4)c3n2)c1.Cc1cccc(-c2ccc3cccc(C(=O)Nc4nccs4)c3n2)c1.O=C(Nc1cccc2ccc(-c3ccccc3)nc12)c1cnccn1.O=C(Nc1nccs1)c1cccc2ccc(-c3ccccc3)nc12
• InChI: InChI=1S/C22H16F2N4O2.C22H16F2N4O.C21H15F2N3OS.C20H14N4O.C20H15N3OS.C19H13N3OS/c1-22(23,24)30-16-6-2-5-15(12-16)17-9-8-14-4-3-7-18(20(14)27-17)28-21(29)19-13-25-10-11-26-19;1-22(23,24)16-6-2-5-15(12-16)17-9-8-14-4-3-7-18(20(14)27-17)28-21(29)19-13-25-10-11-26-19;1-21(22,23)15-6-2-5-14(10-15)16-9-8-13-4-3-7-17(19(13)25-16)26-20(27)18-11-28-12-24-18;25-20(18-13-21-11-12-22-18)24-17-8-4-7-15-9-10-16(23-19(15)17)14-5-2-1-3-6-14;1-13-4-2-6-15(12-13)17-9-8-14-5-3-7-16(18(14)22-17)19(24)23-20-21-10-11-25-20;23-18(22-19-20-11-12-24-19)15-8-4-7-14-9-10-16(21-17(14)15)13-5-2-1-3-6-13/h2-13H,1H3,(H,28,29);2-13H,1H3,(H,28,29);2-12H,1H3,(H,26,27);1-13H,(H,24,25);2-12H,1H3,(H,21,23,24);1-12H,(H,20,22,23)
• InChIKey: LKDJDRUWEANUSJ-UHFFFAOYSA-N
• XLogP: 29.19
• TPSA: 377.18 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 25
• Rotatable Bonds: 22
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2195.40
LogP ≤ 5	29.19
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide?

The IUPAC name of N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide (CID 159374539) is N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide.

What is the SMILES notation for N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide?

The canonical SMILES for N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide is CC(F)(F)Oc1cccc(-c2ccc3cccc(NC(=O)c4cnccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4cnccn4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4cscn4)c3n2)c1.Cc1cccc(-c2ccc3cccc(C(=O)Nc4nccs4)c3n2)c1.O=C(Nc1cccc2ccc(-c3ccccc3)nc12)c1cnccn1.O=C(Nc1nccs1)c1cccc2ccc(-c3ccccc3)nc12.

What is the InChIKey of N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide?

The InChIKey is LKDJDRUWEANUSJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16F2N4O2.C22H16F2N4O.C21H15F2N3OS.C20H14N4O.C20H15N3OS.C19H13N3OS/c1-22(23,24)30-16-6-2-5-15(12-16)17-9-8-14-4-3-7-18(20(14)27-17)28-21(29)19-13-25-10-11-26-19;1-22(23,24)16-6-2-5-15(12-16)17-9-8-14-4-3-7-18(20(14)27-17)28-21(29)19-13-25-10-11-26-19;1-21(22,23)15-6-2-5-14(10-15)16-9-8-13-4-3-7-17(19(13)25-16)26-20(27)18-11-28-12-24-18;25-20(18-13-21-11-12-22-18)24-17-8-4-7-15-9-10-16(23-19(15)17)14-5-2-1-3-6-14;1-13-4-2-6-15(12-13)17-9-8-14-5-3-7-16(18(14)22-17)19(24)23-20-21-10-11-25-20;23-18(22-19-20-11-12-24-19)15-8-4-7-14-9-10-16(21-17(14)15)13-5-2-1-3-6-13/h2-13H,1H3,(H,28,29);2-13H,1H3,(H,28,29);2-12H,1H3,(H,26,27);1-13H,(H,24,25);2-12H,1H3,(H,21,23,24);1-12H,(H,20,22,23).

What are the key properties of N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide?

N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide has a molecular weight of 2195.40 g/mol, XLogP of 29.19, 22 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide is sourced from PubChem (CID 159374539), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).