2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide

C149H134F2N22O10S3 — CID 161474272

IUPAC2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nc(CN5CCCC5)cs4)c3n2)c1.Cc1cnc(NC(=O)c2cccc3ccc(-c4cccc(OC5CCCCC5)c4)nc23)s1.O=C(Nc1cccc2ccc(-c3cccnc3)nc12)c1cnccn1.O=C(Nc1cccnc1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1ccncn1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1nccs1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12
InChIInChI=1S/C27H25N3O2.C26H24F2N4OS.C26H24N4O2.C26H25N3O2S.C25H23N3O2S.C19H13N5O/c31-27(29-21-9-6-16-28-18-21)24-13-5-7-19-14-15-25(30-26(19)24)20-8-4-12-23(17-20)32-22-10-2-1-3-11-22;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-20(16-34-25)15-32-12-2-3-13-32;31-26(30-24-14-15-27-17-28-24)22-11-5-6-18-12-13-23(29-25(18)22)19-7-4-10-21(16-19)32-20-8-2-1-3-9-20;1-17-16-27-26(32-17)29-25(30)22-12-6-7-18-13-14-23(28-24(18)22)19-8-5-11-21(15-19)31-20-9-3-2-4-10-20;29-24(28-25-26-14-15-31-25)21-11-5-6-17-12-13-22(27-23(17)21)18-7-4-10-20(16-18)30-19-8-2-1-3-9-19;25-19(17-12-21-9-10-22-17)24-16-5-1-3-13-6-7-15(23-18(13)16)14-4-2-8-20-11-14/h4-9,12-18,22H,1-3,10-11H2,(H,29,31);4-11,14,16H,2-3,12-13,15H2,1H3,(H,29,31,33);4-7,10-17,20H,1-3,8-9H2,(H,27,28,30,31);5-8,11-16,20H,2-4,9-10H2,1H3,(H,27,29,30);4-7,10-16,19H,1-3,8-9H2,(H,26,28,29);1-12H,(H,24,25)
InChIKeyWDMUJIRWWAXWOJ-UHFFFAOYSA-N
MW2527.05 g/mol
LogP34.53
Rot. Bonds29

About 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide

2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide (PubChem CID 161474272) has the molecular formula C149H134F2N22O10S3 and a molecular weight of 2527.05 g/mol. Its IUPAC name is 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide.

Molecular Properties

Compound Name2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide
PubChem CID161474272
Molecular FormulaC149H134F2N22O10S3
Molecular Weight2527.05 g/mol
Exact Mass2524.98
IUPAC Name2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nc(CN5CCCC5)cs4)c3n2)c1.Cc1cnc(NC(=O)c2cccc3ccc(-c4cccc(OC5CCCCC5)c4)nc23)s1.O=C(Nc1cccc2ccc(-c3cccnc3)nc12)c1cnccn1.O=C(Nc1cccnc1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1ccncn1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1nccs1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12
InChIInChI=1S/C27H25N3O2.C26H24F2N4OS.C26H24N4O2.C26H25N3O2S.C25H23N3O2S.C19H13N5O/c31-27(29-21-9-6-16-28-18-21)24-13-5-7-19-14-15-25(30-26(19)24)20-8-4-12-23(17-20)32-22-10-2-1-3-11-22;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-20(16-34-25)15-32-12-2-3-13-32;31-26(30-24-14-15-27-17-28-24)22-11-5-6-18-12-13-23(29-25(18)22)19-7-4-10-21(16-19)32-20-8-2-1-3-9-20;1-17-16-27-26(32-17)29-25(30)22-12-6-7-18-13-14-23(28-24(18)22)19-8-5-11-21(15-19)31-20-9-3-2-4-10-20;29-24(28-25-26-14-15-31-25)21-11-5-6-17-12-13-22(27-23(17)21)18-7-4-10-20(16-18)30-19-8-2-1-3-9-19;25-19(17-12-21-9-10-22-17)24-16-5-1-3-13-6-7-15(23-18(13)16)14-4-2-8-20-11-14/h4-9,12-18,22H,1-3,10-11H2,(H,29,31);4-11,14,16H,2-3,12-13,15H2,1H3,(H,29,31,33);4-7,10-17,20H,1-3,8-9H2,(H,27,28,30,31);5-8,11-16,20H,2-4,9-10H2,1H3,(H,27,29,30);4-7,10-16,19H,1-3,8-9H2,(H,26,28,29);1-12H,(H,24,25)
InChIKeyWDMUJIRWWAXWOJ-UHFFFAOYSA-N
XLogP34.53
TPSA408.11 Ų
H-Bond Donors6
H-Bond Acceptors29
Rotatable Bonds29
Heavy Atoms186
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002527.05
LogP ≤ 534.53
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1029

Analyze 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide with MolForge

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Related Compounds

2-[4-(1,1-Difluoroethyl)-2-pyridinyl]-1-(3-fluoro-5-pyrimidin-5-yloxyphenyl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(5-fluoro-4-methyl-1,3-thiazol-2-yl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(1,3-thiazol-2-yl)ethanone;1-(3-methyl-5-pyrimidin-5-yloxyphenyl)-2-(5-methyl-1,3-thiazol-2-yl)ethanone;2-(4-methyl-1,3-thiazol-2-yl)-1-(3-pyrimidin-5-yloxyphenyl)ethanone
CID 123315204
N-[6-[3-(1,1-difluoroethyl)phenyl]pyrido[3,2-d]pyrimidin-4-yl]benzamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-3-(2-morpholin-4-ylethoxy)benzamide;1-[2-[3-(1-fluoroethyl)phenyl]quinolin-8-yl]-2-[3-(pyrrolidin-1-ylmethyl)anilino]ethanone;2-[2-(1-fluoroethyl)-4-pyridinyl]-N-[3-(morpholin-4-ylmethyl)phenyl]quinoline-8-carboxamide;2-[2-(1-fluoroethyl)-4-pyridinyl]-N-pyrimidin-4-ylquinoline-8-carboxamide;3-(2-piperidin-1-ylethoxy)-N-(2-pyridin-3-ylquinolin-8-yl)benzamide
CID 157127951
2-[2-(azetidin-1-yl)-4-pyridinyl]-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethoxy)phenyl]-N-[4-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;bis(N-[2-(4-fluoro-3-methylphenyl)quinolin-8-yl]pyridine-2-carboxamide);N-[2-(6-methyl-3-pyridinyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide
CID 158284343
2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide
CID 158848134
2-[3-(1,1-difluoroethoxy)phenyl]-N-[5-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;2-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-[3-[(2S)-2,3-dihydroxypropoxy]phenyl]ethanone;N,2-diphenylquinoline-8-carboxamide;N-[4-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]-2-pyridin-3-ylquinoline-8-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 158969133
6-(6-Cyclopentyl-4-methyl-3-pyridinyl)-2-[4-(1-methylpiperidin-4-yl)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-(5-cyclopentyl-3-methyl-2-pyridinyl)-2-[4-(oxan-2-yl)anilino]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;2-(3-methyl-4-piperazin-1-ylanilino)-6-(4-methyl-2-pyridin-2-ylpyrimidin-5-yl)-8-(2-morpholin-4-ylethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-3-yl)anilino]-6-(2-methyl-6-pyridin-4-yl-3-pyridinyl)-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-(3-methyl-6-pyridin-3-ylpyrazin-2-yl)-8-(2-oxo-2-pyrrolidin-1-ylethyl)-2-[4-(piperidin-3-ylmethyl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(2-methyl-4-pyrrolidin-2-ylphenyl)-2-(4-pyrrolidin-3-yloxyanilino)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one
CID 159116741
N-[2-[3-(1,1-difluoroethoxy)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]pyrazine-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(3-methylphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;N-(2-phenylquinolin-8-yl)pyrazine-2-carboxamide;2-phenyl-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 159374539
N-[6-[3-(1,1-difluoroethoxy)phenyl]pyrido[3,2-d]pyrimidin-4-yl]-1,3-thiazole-4-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-3-pyridinyl]quinoline-8-carboxamide;2-[3-(1-fluoroethyl)phenyl]-N-[4-(morpholin-4-ylmethyl)phenyl]quinoline-8-carboxamide;7-[3-(1-fluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-2-pyridinyl]naphthalene-1-carboxamide;2-[2-(1-fluoroethyl)-4-pyridinyl]-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 159499663
N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(1,3-dimethyl-2,4-dioxopyrido[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[2,4-difluoro-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-2-(1,3-dimethyl-2,4-dioxopyrido[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxopyrido[2,3-d]pyrimidin-5-yl)-N-[4-(3-fluoro-4-methylphenyl)-1,3-thiazol-2-yl]acetamide;2-(1,3-dimethyl-2,4-dioxopyrido[4,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]acetamide
CID 160287060
8-(6-methoxy-3-pyridinyl)-2-phenyl-3-[(1S)-1-([1,3]thiazolo[4,5-c]pyridin-4-ylamino)ethyl]isoquinolin-1-one;8-(5-methyl-3-pyridinyl)-2-phenyl-3-[(1S)-1-([1,3]thiazolo[4,5-c]pyridin-4-ylamino)ethyl]isoquinolin-1-one;2-phenyl-8-pyrimidin-5-yl-3-[(1S)-1-([1,3]thiazolo[4,5-c]pyridin-4-ylamino)ethyl]isoquinolin-1-one;2-phenyl-3-[(1S)-1-([1,3]thiazolo[4,5-c]pyridin-4-ylamino)ethyl]-8-[2-(trifluoromethyl)-4-pyridinyl]isoquinolin-1-one
CID 160516193
2-[4-(1,1-Difluoroethyl)-2-pyridinyl]-1-(3-fluoro-5-pyrimidin-5-yloxyphenyl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(5-fluoro-4-methyl-1,3-thiazol-2-yl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(1,3-thiazol-2-yl)ethanone;1-(3-methyl-5-pyrimidin-5-yloxyphenyl)-2-(5-methyl-1,3-thiazol-2-yl)ethanone;2-(4-methyl-1,3-thiazol-2-yl)-1-(3-pyridin-3-yloxyphenyl)ethanone
CID 161117012
8-[[2-(Cyclopenten-1-yl)furan-3-yl]methyl]-2-[4-piperazin-1-yl-3-(trifluoromethyl)anilino]-6-(pyridin-3-ylamino)pyrido[2,3-d]pyrimidin-7-one;6-(1-methylpiperidin-2-yl)-8-[(1-pyridin-4-ylimidazol-2-yl)methyl]-2-[4-(1,2,3,6-tetrahydropyridin-4-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-(5-methyl-1,3-thiazol-4-yl)-2-(4-pyrrolidin-3-ylanilino)-8-[(2-pyrrolidin-3-ylpyrazol-3-yl)methyl]pyrido[2,3-d]pyrimidin-7-one;6-(1-phenylethenyl)-2-(4-piperidin-4-ylanilino)-8-[[3-(1,3-thiazol-2-yl)imidazol-4-yl]methyl]pyrido[2,3-d]pyrimidin-7-one
CID 161218983

Frequently Asked Questions

What is the IUPAC name of 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide?
The IUPAC name of 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide (CID 161474272) is 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide.
What is the SMILES notation for 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide?
The canonical SMILES for 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide is CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4nc(CN5CCCC5)cs4)c3n2)c1.Cc1cnc(NC(=O)c2cccc3ccc(-c4cccc(OC5CCCCC5)c4)nc23)s1.O=C(Nc1cccc2ccc(-c3cccnc3)nc12)c1cnccn1.O=C(Nc1cccnc1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1ccncn1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.O=C(Nc1nccs1)c1cccc2ccc(-c3cccc(OC4CCCCC4)c3)nc12.
What is the InChIKey of 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide?
The InChIKey is WDMUJIRWWAXWOJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H25N3O2.C26H24F2N4OS.C26H24N4O2.C26H25N3O2S.C25H23N3O2S.C19H13N5O/c31-27(29-21-9-6-16-28-18-21)24-13-5-7-19-14-15-25(30-26(19)24)20-8-4-12-23(17-20)32-22-10-2-1-3-11-22;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-20(16-34-25)15-32-12-2-3-13-32;31-26(30-24-14-15-27-17-28-24)22-11-5-6-18-12-13-23(29-25(18)22)19-7-4-10-21(16-19)32-20-8-2-1-3-9-20;1-17-16-27-26(32-17)29-25(30)22-12-6-7-18-13-14-23(28-24(18)22)19-8-5-11-21(15-19)31-20-9-3-2-4-10-20;29-24(28-25-26-14-15-31-25)21-11-5-6-17-12-13-22(27-23(17)21)18-7-4-10-20(16-18)30-19-8-2-1-3-9-19;25-19(17-12-21-9-10-22-17)24-16-5-1-3-13-6-7-15(23-18(13)16)14-4-2-8-20-11-14/h4-9,12-18,22H,1-3,10-11H2,(H,29,31);4-11,14,16H,2-3,12-13,15H2,1H3,(H,29,31,33);4-7,10-17,20H,1-3,8-9H2,(H,27,28,30,31);5-8,11-16,20H,2-4,9-10H2,1H3,(H,27,29,30);4-7,10-16,19H,1-3,8-9H2,(H,26,28,29);1-12H,(H,24,25).
What are the key properties of 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide?
2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide has a molecular weight of 2527.05 g/mol, XLogP of 34.53, 29 rotatable bonds, 6 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide is sourced from PubChem (CID 161474272), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).