2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide

C146H126F12N22O9S — CID 158848134

IUPAC2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(CN5CCCC5)n4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(OC[C@H](O)CO)c4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ncc(CN5CCCC5)s4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4ccn[nH]4)c3n2)c1.Cn1ccnc1C(=O)Nc1cccc2ccc(-c3cccc(C(C)(F)F)c3)nc12.Cn1cnc(C(=O)Nc2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)c1
InChIInChI=1S/C28H26F2N4O.C27H24F2N2O4.C26H24F2N4OS.2C22H18F2N4O.C21H16F2N4O/c1-28(29,30)21-9-4-8-20(17-21)24-14-13-19-7-5-11-23(26(19)32-24)27(35)33-25-12-6-10-22(31-25)18-34-15-2-3-16-34;1-27(28,29)19-7-2-6-18(13-19)24-12-11-17-5-3-10-23(25(17)31-24)26(34)30-20-8-4-9-22(14-20)35-16-21(33)15-32;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-15-20(34-25)16-32-12-2-3-13-32;1-22(23,24)16-7-3-6-15(11-16)17-10-9-14-5-4-8-18(20(14)26-17)27-21(29)19-12-28(2)13-25-19;1-22(23,24)16-7-3-6-15(13-16)17-10-9-14-5-4-8-18(19(14)26-17)27-21(29)20-25-11-12-28(20)2;1-21(22,23)15-6-2-5-14(12-15)16-9-8-13-4-3-7-17(19(13)25-16)26-20(28)18-10-11-24-27-18/h4-14,17H,2-3,15-16,18H2,1H3,(H,31,33,35);2-14,21,32-33H,15-16H2,1H3,(H,30,34);4-11,14-15H,2-3,12-13,16H2,1H3,(H,29,31,33);2*3-13H,1-2H3,(H,27,29);2-12H,1H3,(H,24,27)(H,26,28)/t;21-;;;;/m.1..../s1
InChIKeyIZCGRYSWCLPDAM-DRUIFJEQSA-N
MW2592.80 g/mol
LogP32.56
Rot. Bonds32

About 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide

2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide (PubChem CID 158848134) has the molecular formula C146H126F12N22O9S and a molecular weight of 2592.80 g/mol. Its IUPAC name is 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide.

Molecular Properties

Compound Name2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide
PubChem CID158848134
Molecular FormulaC146H126F12N22O9S
Molecular Weight2592.80 g/mol
Exact Mass2590.96
IUPAC Name2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide
SMILESCC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(CN5CCCC5)n4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(OC[C@H](O)CO)c4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ncc(CN5CCCC5)s4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4ccn[nH]4)c3n2)c1.Cn1ccnc1C(=O)Nc1cccc2ccc(-c3cccc(C(C)(F)F)c3)nc12.Cn1cnc(C(=O)Nc2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)c1
InChIInChI=1S/C28H26F2N4O.C27H24F2N2O4.C26H24F2N4OS.2C22H18F2N4O.C21H16F2N4O/c1-28(29,30)21-9-4-8-20(17-21)24-14-13-19-7-5-11-23(26(19)32-24)27(35)33-25-12-6-10-22(31-25)18-34-15-2-3-16-34;1-27(28,29)19-7-2-6-18(13-19)24-12-11-17-5-3-10-23(25(17)31-24)26(34)30-20-8-4-9-22(14-20)35-16-21(33)15-32;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-15-20(34-25)16-32-12-2-3-13-32;1-22(23,24)16-7-3-6-15(11-16)17-10-9-14-5-4-8-18(20(14)26-17)27-21(29)19-12-28(2)13-25-19;1-22(23,24)16-7-3-6-15(13-16)17-10-9-14-5-4-8-18(19(14)26-17)27-21(29)20-25-11-12-28(20)2;1-21(22,23)15-6-2-5-14(12-15)16-9-8-13-4-3-7-17(19(13)25-16)26-20(28)18-10-11-24-27-18/h4-14,17H,2-3,15-16,18H2,1H3,(H,31,33,35);2-14,21,32-33H,15-16H2,1H3,(H,30,34);4-11,14-15H,2-3,12-13,16H2,1H3,(H,29,31,33);2*3-13H,1-2H3,(H,27,29);2-12H,1H3,(H,24,27)(H,26,28)/t;21-;;;;/m.1..../s1
InChIKeyIZCGRYSWCLPDAM-DRUIFJEQSA-N
XLogP32.56
TPSA398.21 Ų
H-Bond Donors9
H-Bond Acceptors25
Rotatable Bonds32
Heavy Atoms190
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002592.80
LogP ≤ 532.56
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1025

Analyze 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-(3-cyclohexyloxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)quinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyridin-3-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-pyrimidin-4-ylquinoline-8-carboxamide;2-(3-cyclohexyloxyphenyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[4-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-(2-pyridin-3-ylquinolin-8-yl)pyrazine-2-carboxamide
CID 161474272
N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-6-[(3R)-3,4-dihydroxybutyl]pyridine-2-carboxamide;N-[2-(3-methylphenyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;N-[2-(2-methyl-3-pyridinyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;N-[2-(6-methyl-3-pyridinyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;N-[2-(3-piperidin-1-ylphenyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;N-[6-[3-(trifluoromethoxy)phenyl]pyrido[3,2-d]pyrimidin-4-yl]pyridine-2-carboxamide
CID 161766069
2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2S)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-3-(dimethylamino)benzamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-3-[(4-methylpiperazin-1-yl)methyl]benzamide;N-[2-(3,4-dimethylphenyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;N-[2-(5-methyl-3-pyridinyl)quinolin-8-yl]-1,3-thiazole-4-carboxamide;2-(2-piperidin-1-yl-4-pyridinyl)-N-(1,3-thiazol-2-yl)quinoline-8-carboxamide
CID 161788970
N-tert-butyl-1-(5-fluorothiophen-2-yl)-7-methoxy-N-methyl-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinoline-3-carboxamide;N-tert-butyl-7-methoxy-N-methyl-8-(2-methylpropyl)-1-(1H-pyrazol-5-yl)-4,5-dihydroimidazo[1,5-a]quinoline-3-carboxamide;N-tert-butyl-7-methoxy-N-methyl-1-(1-methylpyrrol-3-yl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinoline-3-carboxamide;N-tert-butyl-7-methoxy-N-methyl-1-(2-methyl-1,3-thiazol-5-yl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinoline-3-carboxamide;N-tert-butyl-7-methoxy-N-methyl-8-propan-2-yloxy-1-pyridin-4-yl-4,5-dihydroimidazo[1,5-a]quinoline-3-carboxamide
CID 161606022
4-(cyclopropylmethoxy)-2-(4-fluorophenyl)-N-[3-(1H-imidazol-2-yl)propyl]quinazoline-7-carboxamide;4-ethoxy-2-(ethylamino)-N-[3-(1H-imidazol-2-yl)propyl]quinazoline-7-carboxamide;4-ethoxy-2-(4-fluorophenyl)-N-(3-pyrazol-1-ylpropyl)quinoline-7-carboxamide;4-ethoxy-2-(4-fluorophenyl)-N-(3-pyridazin-4-ylpropyl)quinoline-7-carboxamide;4-ethoxy-2-(4-fluorophenyl)-N-[3-(1,3-thiazol-2-yl)propyl]quinoline-7-carboxamide;4-(ethylamino)-2-(4-fluorophenyl)-N-[3-(1H-imidazol-2-yl)propyl]quinazoline-7-carboxamide
CID 161870425
N-(1H-benzimidazol-2-yl)-2-methylpropanamide;N-(1,3-benzoxazol-2-yl)-2-methylpropanamide;N-[4-[(2S)-2,3-dihydroxypropoxy]pyrimidin-2-yl]-2-methylpropanamide;N-[4-[(2R)-2,3-dihydroxypropoxy]pyrimidin-2-yl]-2-methylpropanamide;N-[5-[(2R)-2,3-dihydroxypropoxy]pyrimidin-2-yl]-2-methylpropanamide;N-[5-[(2S)-2,3-dihydroxypropoxy]pyrimidin-2-yl]-2-methylpropanamide;N-[4-(1,3-dimethylpyrazol-4-yl)pyrimidin-2-yl]-2-methylpropanamide;N-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpropanamide;N-(5-fluoroquinazolin-4-yl)-2-methylpropanamide;2-methyl-N-[4-(2-methyl-1,3-oxazol-5-yl)pyrimidin-2-yl]propanamide;2-methyl-N-(6-methyl-1H-pyrazolo[5,4-b]pyridin-3-yl)propanamide;2-methyl-N-[4-(1-methylpyrazol-4-yl)pyrimidin-2-yl]propanamide;2-methyl-N-[4-(1,3-oxazol-5-yl)pyrimidin-2-yl]propanamide;2-methyl-N-(4-phenylpyrimidin-2-yl)propanamide
CID 162056870

Frequently Asked Questions

What is the IUPAC name of 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide?
The IUPAC name of 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide (CID 158848134) is 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide.
What is the SMILES notation for 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide?
The canonical SMILES for 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide is CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(CN5CCCC5)n4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4cccc(OC[C@H](O)CO)c4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(C(=O)Nc4ncc(CN5CCCC5)s4)c3n2)c1.CC(F)(F)c1cccc(-c2ccc3cccc(NC(=O)c4ccn[nH]4)c3n2)c1.Cn1ccnc1C(=O)Nc1cccc2ccc(-c3cccc(C(C)(F)F)c3)nc12.Cn1cnc(C(=O)Nc2cccc3ccc(-c4cccc(C(C)(F)F)c4)nc23)c1.
What is the InChIKey of 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide?
The InChIKey is IZCGRYSWCLPDAM-DRUIFJEQSA-N. The full InChI is InChI=1S/C28H26F2N4O.C27H24F2N2O4.C26H24F2N4OS.2C22H18F2N4O.C21H16F2N4O/c1-28(29,30)21-9-4-8-20(17-21)24-14-13-19-7-5-11-23(26(19)32-24)27(35)33-25-12-6-10-22(31-25)18-34-15-2-3-16-34;1-27(28,29)19-7-2-6-18(13-19)24-12-11-17-5-3-10-23(25(17)31-24)26(34)30-20-8-4-9-22(14-20)35-16-21(33)15-32;1-26(27,28)19-8-4-7-18(14-19)22-11-10-17-6-5-9-21(23(17)30-22)24(33)31-25-29-15-20(34-25)16-32-12-2-3-13-32;1-22(23,24)16-7-3-6-15(11-16)17-10-9-14-5-4-8-18(20(14)26-17)27-21(29)19-12-28(2)13-25-19;1-22(23,24)16-7-3-6-15(13-16)17-10-9-14-5-4-8-18(19(14)26-17)27-21(29)20-25-11-12-28(20)2;1-21(22,23)15-6-2-5-14(12-15)16-9-8-13-4-3-7-17(19(13)25-16)26-20(28)18-10-11-24-27-18/h4-14,17H,2-3,15-16,18H2,1H3,(H,31,33,35);2-14,21,32-33H,15-16H2,1H3,(H,30,34);4-11,14-15H,2-3,12-13,16H2,1H3,(H,29,31,33);2*3-13H,1-2H3,(H,27,29);2-12H,1H3,(H,24,27)(H,26,28)/t;21-;;;;/m.1..../s1.
What are the key properties of 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide?
2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide has a molecular weight of 2592.80 g/mol, XLogP of 32.56, 32 rotatable bonds, 9 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[3-(1,1-difluoroethyl)phenyl]-N-[3-[(2R)-2,3-dihydroxypropoxy]phenyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[6-(pyrrolidin-1-ylmethyl)-2-pyridinyl]quinoline-8-carboxamide;2-[3-(1,1-difluoroethyl)phenyl]-N-[5-(pyrrolidin-1-ylmethyl)-1,3-thiazol-2-yl]quinoline-8-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-2-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1-methylimidazole-4-carboxamide;N-[2-[3-(1,1-difluoroethyl)phenyl]quinolin-8-yl]-1H-pyrazole-5-carboxamide is sourced from PubChem (CID 158848134), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).