6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one

C112H89F3N36O10 — CID 159375720

About 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one

6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one (PubChem CID 159375720) has the molecular formula C112H89F3N36O10 and a molecular weight of 2156.18 g/mol. Its IUPAC name is 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one.

Molecular Properties

• Compound Name: 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one
• PubChem CID: 159375720
• Molecular Formula: C112H89F3N36O10
• Molecular Weight: 2156.18 g/mol
• Exact Mass: 2154.75
• IUPAC Name: 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one
• SMILES: Cc1cc(-c2cc(F)c3nnc([C@@H](C)n4ccc5ncccc5c4=O)n3c2)on1.Cc1cc(-c2cc(F)c3nnc([C@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1.Cc1cc(-c2cc(F)c3nnc([C@H](C)n4ccc5ncccc5c4=O)n3c2)on1.Cc1cc(-c2ccc3nnc([C@@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1.Cc1cc(-c2ccc3nnc([C@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1
• InChI: InChI=1S/C24H19FN8O2.2C24H20N8O2.2C20H15FN6O2/c1-13-6-21(35-30-13)16-8-19(25)23-29-28-22(33(23)12-16)14(2)32-5-4-20-18(24(32)34)7-15(9-26-20)17-10-27-31(3)11-17;2*1-14-8-21(34-29-14)16-4-5-22-27-28-23(32(22)13-16)15(2)31-7-6-20-19(24(31)33)9-17(10-25-20)18-11-26-30(3)12-18;2*1-11-8-17(29-25-11)13-9-15(21)19-24-23-18(27(19)10-13)12(2)26-7-5-16-14(20(26)28)4-3-6-22-16/h4-12,14H,1-3H3;2*4-13,15H,1-3H3;2*3-10,12H,1-2H3/t14-;2*15-;2*12-/m01010/s1
• InChIKey: LKHHBHXFGFHPLF-CZLUPPJBSA-N
• XLogP: 16.68
• TPSA: 509.01 Ų
• H-Bond Acceptors: 46
• Rotatable Bonds: 18
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2156.18
LogP ≤ 5	16.68
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	46

Frequently Asked Questions

What is the IUPAC name of 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one?

The IUPAC name of 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one (CID 159375720) is 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one.

What is the SMILES notation for 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one?

The canonical SMILES for 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one is Cc1cc(-c2cc(F)c3nnc([C@@H](C)n4ccc5ncccc5c4=O)n3c2)on1.Cc1cc(-c2cc(F)c3nnc([C@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1.Cc1cc(-c2cc(F)c3nnc([C@H](C)n4ccc5ncccc5c4=O)n3c2)on1.Cc1cc(-c2ccc3nnc([C@@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1.Cc1cc(-c2ccc3nnc([C@H](C)n4ccc5ncc(-c6cnn(C)c6)cc5c4=O)n3c2)on1.

What is the InChIKey of 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one?

The InChIKey is LKHHBHXFGFHPLF-CZLUPPJBSA-N. The full InChI is InChI=1S/C24H19FN8O2.2C24H20N8O2.2C20H15FN6O2/c1-13-6-21(35-30-13)16-8-19(25)23-29-28-22(33(23)12-16)14(2)32-5-4-20-18(24(32)34)7-15(9-26-20)17-10-27-31(3)11-17;2*1-14-8-21(34-29-14)16-4-5-22-27-28-23(32(22)13-16)15(2)31-7-6-20-19(24(31)33)9-17(10-25-20)18-11-26-30(3)12-18;2*1-11-8-17(29-25-11)13-9-15(21)19-24-23-18(27(19)10-13)12(2)26-7-5-16-14(20(26)28)4-3-6-22-16/h4-12,14H,1-3H3;2*4-13,15H,1-3H3;2*3-10,12H,1-2H3/t14-;2*15-;2*12-/m01010/s1.

What are the key properties of 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one?

6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one has a molecular weight of 2156.18 g/mol, XLogP of 16.68, 18 rotatable bonds, 0 hydrogen bond donors, and 46 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one;6-[(1S)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one;6-[(1R)-1-[6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(1-methylpyrazol-4-yl)-1,6-naphthyridin-5-one is sourced from PubChem (CID 159375720), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).