N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide

C116H100Br2F5N27O14S5 — CID 159389836

About N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide

N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 159389836) has the molecular formula C116H100Br2F5N27O14S5 and a molecular weight of 2511.38 g/mol. Its IUPAC name is N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 159389836
• Molecular Formula: C116H100Br2F5N27O14S5
• Molecular Weight: 2511.38 g/mol
• Exact Mass: 2507.48
• IUPAC Name: N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC(=O)N(C)c1ncc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)s1.CC[C@@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)cn1S(=O)(=O)c1ccc(C)cc1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)cn1S(=O)(=O)c1ccc(C)cc1.C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(S(C)(=O)=O)[nH]c(=O)c1.O=C(NCc1cnc(N2CCOCC2)s1)c1cncc2c1cnn2-c1ccc(F)cc1
• InChI: InChI=1S/2C27H23BrFN5O3S.C21H19FN6O2S.C21H18FN5O4S.C20H17FN6O2S/c2*1-3-24(25-12-18(28)16-33(25)38(36,37)21-10-4-17(2)5-11-21)32-27(35)23-13-30-15-26-22(23)14-31-34(26)20-8-6-19(29)7-9-20;22-14-1-3-15(4-2-14)28-19-13-23-11-18(17(19)12-26-28)20(29)24-9-16-10-25-21(31-16)27-5-7-30-8-6-27;1-12(13-7-19(28)26-20(8-13)32(2,30)31)25-21(29)17-9-23-11-18-16(17)10-24-27(18)15-5-3-14(22)4-6-15;1-12(28)26(2)20-24-8-15(30-20)7-23-19(29)17-9-22-11-18-16(17)10-25-27(18)14-5-3-13(21)4-6-14/h2*4-16,24H,3H2,1-2H3,(H,32,35);1-4,10-13H,5-9H2,(H,24,29);3-12H,1-2H3,(H,25,29)(H,26,28);3-6,8-11H,7H2,1-2H3,(H,23,29)/t2*24-;;12-;/m10.0./s1
• InChIKey: LLYWOLIBWWPDMK-FVYFTSECSA-N
• XLogP: 18.95
• TPSA: 502.75 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 36
• Rotatable Bonds: 29
• Heavy Atoms: 169
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2511.38
LogP ≤ 5	18.95
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide (CID 159389836) is N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide is CC(=O)N(C)c1ncc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)s1.CC[C@@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)cn1S(=O)(=O)c1ccc(C)cc1.CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)cn1S(=O)(=O)c1ccc(C)cc1.C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(S(C)(=O)=O)[nH]c(=O)c1.O=C(NCc1cnc(N2CCOCC2)s1)c1cncc2c1cnn2-c1ccc(F)cc1.

What is the InChIKey of N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is LLYWOLIBWWPDMK-FVYFTSECSA-N. The full InChI is InChI=1S/2C27H23BrFN5O3S.C21H19FN6O2S.C21H18FN5O4S.C20H17FN6O2S/c2*1-3-24(25-12-18(28)16-33(25)38(36,37)21-10-4-17(2)5-11-21)32-27(35)23-13-30-15-26-22(23)14-31-34(26)20-8-6-19(29)7-9-20;22-14-1-3-15(4-2-14)28-19-13-23-11-18(17(19)12-26-28)20(29)24-9-16-10-25-21(31-16)27-5-7-30-8-6-27;1-12(13-7-19(28)26-20(8-13)32(2,30)31)25-21(29)17-9-23-11-18-16(17)10-24-27(18)15-5-3-14(22)4-6-15;1-12(28)26(2)20-24-8-15(30-20)7-23-19(29)17-9-22-11-18-16(17)10-25-27(18)14-5-3-13(21)4-6-14/h2*4-16,24H,3H2,1-2H3,(H,32,35);1-4,10-13H,5-9H2,(H,24,29);3-12H,1-2H3,(H,25,29)(H,26,28);3-6,8-11H,7H2,1-2H3,(H,23,29)/t2*24-;;12-;/m10.0./s1.

What are the key properties of N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide?

N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2511.38 g/mol, XLogP of 18.95, 29 rotatable bonds, 6 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for N-[[2-[acetyl(methyl)amino]-1,3-thiazol-5-yl]methyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1R)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[4-bromo-1-(4-methylphenyl)sulfonylpyrrol-2-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-6-oxo-1H-pyridin-4-yl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-morpholin-4-yl-1,3-thiazol-5-yl)methyl]pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 159389836), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).