N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide

C168H170F8N28O18 — CID 159405697

About N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide

N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide (PubChem CID 159405697) has the molecular formula C168H170F8N28O18 and a molecular weight of 3021.37 g/mol. Its IUPAC name is N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide.

Molecular Properties

• Compound Name: N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide
• PubChem CID: 159405697
• Molecular Formula: C168H170F8N28O18
• Molecular Weight: 3021.37 g/mol
• Exact Mass: 3019.31
• IUPAC Name: N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide
• SMILES: CCC(=O)C1Cc2ncc(-c3cc(NC(=O)c4ccnc(C(C)(F)F)c4)ccc3C)cc2N2CCOCC12.CCC(=O)NC1CC2COCCN2c2cc(-c3cc(NC(=O)c4ccnc(C(F)(F)F)c4)ccc3C)cnc21.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc2c(c1)N1CCOCC1C1(COC1)C2.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOCC3CC4O)c2)ccn1.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOC[C@@H]3C[C@@H]4O)c2)ccn1.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOC[C@H]3C[C@H]4O)c2)ccn1
• InChI: InChI=1S/C29H30F2N4O3.C28H28F3N5O3.3C28H29N5O3.C27H25F3N4O3/c1-4-26(36)22-14-23-24(35-9-10-38-16-25(22)35)11-19(15-33-23)21-13-20(6-5-17(21)2)34-28(37)18-7-8-32-27(12-18)29(3,30)31;1-3-25(37)35-22-13-20-15-39-9-8-36(20)23-10-18(14-33-26(22)23)21-12-19(5-4-16(21)2)34-27(38)17-6-7-32-24(11-17)28(29,30)31;3*1-17-5-6-20(32-27(35)18-7-8-30-25(12-18)28(2,3)29-4)13-22(17)19-11-23-26(31-15-19)24(34)14-21-16-36-10-9-33(21)23;1-16-21(9-20(12-31-16)33-25(35)17-3-2-4-19(7-17)27(28,29)30)18-8-23-22(32-11-18)10-26(14-37-15-26)24-13-36-6-5-34(23)24/h5-8,11-13,15,22,25H,4,9-10,14,16H2,1-3H3,(H,34,37);4-7,10-12,14,20,22H,3,8-9,13,15H2,1-2H3,(H,34,38)(H,35,37);3*5-8,11-13,15,21,24,34H,9-10,14,16H2,1-3H3,(H,32,35);2-4,7-9,11-12,24H,5-6,10,13-15H2,1H3,(H,33,35)/t;;2*21-,24-;;/m..10../s1
• InChIKey: LNXPKCCQASYEDQ-ZPJNPUQJSA-N
• XLogP: 28.08
• TPSA: 533.27 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 36
• Rotatable Bonds: 26
• Heavy Atoms: 222
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3021.37
LogP ≤ 5	28.08
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	36

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide?

The IUPAC name of N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide (CID 159405697) is N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide.

What is the SMILES notation for N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide?

The canonical SMILES for N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide is CCC(=O)C1Cc2ncc(-c3cc(NC(=O)c4ccnc(C(C)(F)F)c4)ccc3C)cc2N2CCOCC12.CCC(=O)NC1CC2COCCN2c2cc(-c3cc(NC(=O)c4ccnc(C(F)(F)F)c4)ccc3C)cnc21.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc2c(c1)N1CCOCC1C1(COC1)C2.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOCC3CC4O)c2)ccn1.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOC[C@@H]3C[C@@H]4O)c2)ccn1.[C-]#[N+]C(C)(C)c1cc(C(=O)Nc2ccc(C)c(-c3cnc4c(c3)N3CCOC[C@H]3C[C@H]4O)c2)ccn1.

What is the InChIKey of N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide?

The InChIKey is LNXPKCCQASYEDQ-ZPJNPUQJSA-N. The full InChI is InChI=1S/C29H30F2N4O3.C28H28F3N5O3.3C28H29N5O3.C27H25F3N4O3/c1-4-26(36)22-14-23-24(35-9-10-38-16-25(22)35)11-19(15-33-23)21-13-20(6-5-17(21)2)34-28(37)18-7-8-32-27(12-18)29(3,30)31;1-3-25(37)35-22-13-20-15-39-9-8-36(20)23-10-18(14-33-26(22)23)21-12-19(5-4-16(21)2)34-27(38)17-6-7-32-24(11-17)28(29,30)31;3*1-17-5-6-20(32-27(35)18-7-8-30-25(12-18)28(2,3)29-4)13-22(17)19-11-23-26(31-15-19)24(34)14-21-16-36-10-9-33(21)23;1-16-21(9-20(12-31-16)33-25(35)17-3-2-4-19(7-17)27(28,29)30)18-8-23-22(32-11-18)10-26(14-37-15-26)24-13-36-6-5-34(23)24/h5-8,11-13,15,22,25H,4,9-10,14,16H2,1-3H3,(H,34,37);4-7,10-12,14,20,22H,3,8-9,13,15H2,1-2H3,(H,34,38)(H,35,37);3*5-8,11-13,15,21,24,34H,9-10,14,16H2,1-3H3,(H,32,35);2-4,7-9,11-12,24H,5-6,10,13-15H2,1H3,(H,33,35)/t;;2*21-,24-;;/m..10../s1.

What are the key properties of N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide?

N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide has a molecular weight of 3021.37 g/mol, XLogP of 28.08, 26 rotatable bonds, 10 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3-[(4aR,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(5-propanoyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)phenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(2-isocyanopropan-2-yl)pyridine-4-carboxamide;N-[4-methyl-3-[6-(propanoylamino)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-(6-methyl-5-spiro[2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridine-5,3'-oxetane]-9-yl-3-pyridinyl)-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 159405697), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).