N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide

C146H142F2N38O12 — CID 159418813

IUPACN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
SMILESCc1ccc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)C)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1
InChIInChI=1S/C26H26N8O2.C26H25N7O2.C25H23F2N5O2.C25H24N8O2.C22H21N5O2.C22H23N5O2/c1-16-22(18-8-17(11-27)24(30-12-18)32-20-4-6-36-7-5-20)10-21(14-29-16)33-25(35)19-9-23(34-31-13-19)26(2,3)15-28;1-17-4-5-21(31-25(34)20-11-23(32-30-15-20)26(2,3)16-28)12-22(17)19-10-18(13-27)24(29-14-19)33-6-8-35-9-7-33;1-15-4-5-19(31-23(33)21-9-18(6-7-29-21)25(3,26)27)10-20(15)17-8-16(11-28)22(30-12-17)32-13-24(2,34)14-32;1-16-21(18-8-17(11-26)23(29-12-18)33-4-6-35-7-5-33)10-20(14-28-16)31-24(34)19-9-22(32-30-13-19)25(2,3)15-27;1-13-4-7-17(25-22(28)19-10-20(29-26-19)14-5-6-14)9-18(13)16-8-15(11-23)21(24-12-16)27(2)3;1-13(2)20-10-19(26-29-20)22(28)25-17-7-6-14(3)18(9-17)16-8-15(11-23)21(24-12-16)27(4)5/h8-10,12-14,20H,4-7H2,1-3H3,(H,30,32)(H,33,35);4-5,10-12,14-15H,6-9H2,1-3H3,(H,31,34);4-10,12,34H,13-14H2,1-3H3,(H,31,33);8-10,12-14H,4-7H2,1-3H3,(H,31,34);4,7-10,12,14H,5-6H2,1-3H3,(H,25,28);6-10,12-13H,1-5H3,(H,25,28)
InChIKeyLPMSNLCHMNEIST-UHFFFAOYSA-N
MW2658.99 g/mol
LogP23.10
Rot. Bonds31

About N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide

N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide (PubChem CID 159418813) has the molecular formula C146H142F2N38O12 and a molecular weight of 2658.99 g/mol. Its IUPAC name is N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide.

Molecular Properties

Compound NameN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
PubChem CID159418813
Molecular FormulaC146H142F2N38O12
Molecular Weight2658.99 g/mol
Exact Mass2657.16
IUPAC NameN-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
SMILESCc1ccc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)C)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1
InChIInChI=1S/C26H26N8O2.C26H25N7O2.C25H23F2N5O2.C25H24N8O2.C22H21N5O2.C22H23N5O2/c1-16-22(18-8-17(11-27)24(30-12-18)32-20-4-6-36-7-5-20)10-21(14-29-16)33-25(35)19-9-23(34-31-13-19)26(2,3)15-28;1-17-4-5-21(31-25(34)20-11-23(32-30-15-20)26(2,3)16-28)12-22(17)19-10-18(13-27)24(29-14-19)33-6-8-35-9-7-33;1-15-4-5-19(31-23(33)21-9-18(6-7-29-21)25(3,26)27)10-20(15)17-8-16(11-28)22(30-12-17)32-13-24(2,34)14-32;1-16-21(18-8-17(11-26)23(29-12-18)33-4-6-35-7-5-33)10-20(14-28-16)31-24(34)19-9-22(32-30-13-19)25(2,3)15-27;1-13-4-7-17(25-22(28)19-10-20(29-26-19)14-5-6-14)9-18(13)16-8-15(11-23)21(24-12-16)27(2)3;1-13(2)20-10-19(26-29-20)22(28)25-17-7-6-14(3)18(9-17)16-8-15(11-23)21(24-12-16)27(4)5/h8-10,12-14,20H,4-7H2,1-3H3,(H,30,32)(H,33,35);4-5,10-12,14-15H,6-9H2,1-3H3,(H,31,34);4-10,12,34H,13-14H2,1-3H3,(H,31,33);8-10,12-14H,4-7H2,1-3H3,(H,31,34);4,7-10,12,14H,5-6H2,1-3H3,(H,25,28);6-10,12-13H,1-5H3,(H,25,28)
InChIKeyLPMSNLCHMNEIST-UHFFFAOYSA-N
XLogP23.10
TPSA710.27 Ų
H-Bond Donors8
H-Bond Acceptors44
Rotatable Bonds31
Heavy Atoms198
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002658.99
LogP ≤ 523.10
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1044

Analyze N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-2-ethyl-3-oxo-4-(trifluoromethyl)-2H-pyridine-6-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157313884
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157366244
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157392965
N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-cyclopropylpyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 157641999
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 157699374
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157707307
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157782406
N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-cyclopropylpyridazine-4-carboxamide;N-[3-(5-cyano-6-piperazin-1-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 157873507
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-cyclopropyl-1-methylpyrazole-5-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 158126779
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2-(3-methyl-1,2-oxazol-5-yl)acetamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 158384163
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2-(3-methyl-1,2-oxazol-5-yl)acetamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 158903727
N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-cyclopropylpyridazine-4-carboxamide;N-[3-(5-cyano-6-piperazin-1-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide
CID 159113885

Frequently Asked Questions

What is the IUPAC name of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide?
The IUPAC name of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide (CID 159418813) is N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide.
What is the SMILES notation for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide?
The canonical SMILES for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide is Cc1ccc(NC(=O)c2cc(C(C)(F)F)ccn2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)C)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C3CC3)on2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ccc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ncc(NC(=O)c2cnnc(C(C)(C)C#N)c2)cc1-c1cnc(NC2CCOCC2)c(C#N)c1.
What is the InChIKey of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide?
The InChIKey is LPMSNLCHMNEIST-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H26N8O2.C26H25N7O2.C25H23F2N5O2.C25H24N8O2.C22H21N5O2.C22H23N5O2/c1-16-22(18-8-17(11-27)24(30-12-18)32-20-4-6-36-7-5-20)10-21(14-29-16)33-25(35)19-9-23(34-31-13-19)26(2,3)15-28;1-17-4-5-21(31-25(34)20-11-23(32-30-15-20)26(2,3)16-28)12-22(17)19-10-18(13-27)24(29-14-19)33-6-8-35-9-7-33;1-15-4-5-19(31-23(33)21-9-18(6-7-29-21)25(3,26)27)10-20(15)17-8-16(11-28)22(30-12-17)32-13-24(2,34)14-32;1-16-21(18-8-17(11-26)23(29-12-18)33-4-6-35-7-5-33)10-20(14-28-16)31-24(34)19-9-22(32-30-13-19)25(2,3)15-27;1-13-4-7-17(25-22(28)19-10-20(29-26-19)14-5-6-14)9-18(13)16-8-15(11-23)21(24-12-16)27(2)3;1-13(2)20-10-19(26-29-20)22(28)25-17-7-6-14(3)18(9-17)16-8-15(11-23)21(24-12-16)27(4)5/h8-10,12-14,20H,4-7H2,1-3H3,(H,30,32)(H,33,35);4-5,10-12,14-15H,6-9H2,1-3H3,(H,31,34);4-10,12,34H,13-14H2,1-3H3,(H,31,33);8-10,12-14H,4-7H2,1-3H3,(H,31,34);4,7-10,12,14H,5-6H2,1-3H3,(H,25,28);6-10,12-13H,1-5H3,(H,25,28).
What are the key properties of N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide?
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide has a molecular weight of 2658.99 g/mol, XLogP of 23.10, 31 rotatable bonds, 8 hydrogen bond donors, and 44 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-cyclopropyl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-5-propan-2-yl-1,2-oxazole-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(1,1-difluoroethyl)pyridine-2-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-6-(2-cyanopropan-2-yl)pyridazine-4-carboxamide is sourced from PubChem (CID 159418813), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).