3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one

C150H143ClF2N24O9 — CID 159473816

IUPAC3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
SMILESCC(Oc1ccc2c(=O)n3c(nc2c1)CCC(C)(C)C3)c1ccccn1.CC1(C)CCc2nc3cc(/C(Cl)=C/c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4ccc(C#N)cn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(CC(=O)c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCn2c(nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c2=O)C1.CC1Cc2nc3cc(/C=C/c4ccccn4)ccc3c(=O)n2CCC1(F)F
InChIInChI=1S/3C22H20N4O.C21H20ClN3O.C21H19F2N3O.C21H23N3O2.C21H21N3O2/c1-22(2)10-9-20-25-19-11-15(5-8-18(19)21(27)26(20)14-22)3-6-17-7-4-16(12-23)13-24-17;1-22(2)9-7-20-25-19-12-15(4-6-18(19)21(27)26(20)14-22)3-5-17-11-16(13-23)8-10-24-17;1-22(2)8-10-26-20(13-22)25-19-12-15(4-6-18(19)21(26)27)3-5-17-11-16(14-23)7-9-24-17;1-21(2)9-8-19-24-18-11-14(6-7-16(18)20(26)25(19)13-21)17(22)12-15-5-3-4-10-23-15;1-14-12-19-25-18-13-15(5-7-16-4-2-3-10-24-16)6-8-17(18)20(27)26(19)11-9-21(14,22)23;1-14(17-6-4-5-11-22-17)26-15-7-8-16-18(12-15)23-19-9-10-21(2,3)13-24(19)20(16)25;1-21(2)9-8-19-23-17-11-14(6-7-15(17)20(26)24(19)13-21)12-18(25)16-5-3-4-10-22-16/h3-8,11,13H,9-10,14H2,1-2H3;3-6,8,10-12H,7,9,14H2,1-2H3;3-7,9,11-12H,8,10,13H2,1-2H3;3-7,10-12H,8-9,13H2,1-2H3;2-8,10,13-14H,9,11-12H2,1H3;4-8,11-12,14H,9-10,13H2,1-3H3;3-7,10-11H,8-9,12-13H2,1-2H3/b6-3+;2*5-3+;17-12-;7-5+;;
InChIKeyLWCZESDRAQTEAT-SZRHLZNOSA-N
MW2499.40 g/mol
LogP27.19
Rot. Bonds16

About 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one

3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one (PubChem CID 159473816) has the molecular formula C150H143ClF2N24O9 and a molecular weight of 2499.40 g/mol. Its IUPAC name is 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one.

Molecular Properties

Compound Name3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
PubChem CID159473816
Molecular FormulaC150H143ClF2N24O9
Molecular Weight2499.40 g/mol
Exact Mass2497.11
IUPAC Name3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
SMILESCC(Oc1ccc2c(=O)n3c(nc2c1)CCC(C)(C)C3)c1ccccn1.CC1(C)CCc2nc3cc(/C(Cl)=C/c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4ccc(C#N)cn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(CC(=O)c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCn2c(nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c2=O)C1.CC1Cc2nc3cc(/C=C/c4ccccn4)ccc3c(=O)n2CCC1(F)F
InChIInChI=1S/3C22H20N4O.C21H20ClN3O.C21H19F2N3O.C21H23N3O2.C21H21N3O2/c1-22(2)10-9-20-25-19-11-15(5-8-18(19)21(27)26(20)14-22)3-6-17-7-4-16(12-23)13-24-17;1-22(2)9-7-20-25-19-12-15(4-6-18(19)21(27)26(20)14-22)3-5-17-11-16(13-23)8-10-24-17;1-22(2)8-10-26-20(13-22)25-19-12-15(4-6-18(19)21(26)27)3-5-17-11-16(14-23)7-9-24-17;1-21(2)9-8-19-24-18-11-14(6-7-16(18)20(26)25(19)13-21)17(22)12-15-5-3-4-10-23-15;1-14-12-19-25-18-13-15(5-7-16-4-2-3-10-24-16)6-8-17(18)20(27)26(19)11-9-21(14,22)23;1-14(17-6-4-5-11-22-17)26-15-7-8-16-18(12-15)23-19-9-10-21(2,3)13-24(19)20(16)25;1-21(2)9-8-19-23-17-11-14(6-7-15(17)20(26)24(19)13-21)12-18(25)16-5-3-4-10-22-16/h3-8,11,13H,9-10,14H2,1-2H3;3-6,8,10-12H,7,9,14H2,1-2H3;3-7,9,11-12H,8,10,13H2,1-2H3;3-7,10-12H,8-9,13H2,1-2H3;2-8,10,13-14H,9,11-12H2,1H3;4-8,11-12,14H,9-10,13H2,1-3H3;3-7,10-11H,8-9,12-13H2,1-2H3/b6-3+;2*5-3+;17-12-;7-5+;;
InChIKeyLWCZESDRAQTEAT-SZRHLZNOSA-N
XLogP27.19
TPSA432.13 Ų
H-Bond Donors
H-Bond Acceptors33
Rotatable Bonds16
Heavy Atoms186
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002499.40
LogP ≤ 527.19
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1033

Analyze 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one with MolForge

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Launch Full Analysis

Related Compounds

8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
CID 158023693
3-[(Z)-2-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-4-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;2-[(E)-2-(8-methyl-12-oxo-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile
CID 160077719
3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;3-[(Z)-2-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;7,7-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[2-(4-methylpyrimidin-2-yl)ethynyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
CID 160583460
3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;3-[(Z)-2-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;7,7-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
CID 160898512
3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;3-[(Z)-2-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;7,7-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
CID 161680365
3-[(Z)-2-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
CID 157492178
8,8-dimethyl-3-(2-pyridin-2-ylacetyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(2-pyridin-2-ylcyclopropyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(pyridin-2-ylmethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-pyridin-2-yloxy-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(pyridin-2-yloxymethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(2-pyridin-2-ylpropanoyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-pyridin-2-ylprop-1-enyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(2-pyridin-2-ylpropyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
CID 159176056
3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;7,7-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-[2-(4-methylpyrimidin-2-yl)ethynyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one
CID 159615734

Frequently Asked Questions

What is the IUPAC name of 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one?
The IUPAC name of 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one (CID 159473816) is 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one.
What is the SMILES notation for 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one?
The canonical SMILES for 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one is CC(Oc1ccc2c(=O)n3c(nc2c1)CCC(C)(C)C3)c1ccccn1.CC1(C)CCc2nc3cc(/C(Cl)=C/c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(/C=C/c4ccc(C#N)cn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(CC(=O)c4ccccn4)ccc3c(=O)n2C1.CC1(C)CCn2c(nc3cc(/C=C/c4cc(C#N)ccn4)ccc3c2=O)C1.CC1Cc2nc3cc(/C=C/c4ccccn4)ccc3c(=O)n2CCC1(F)F.
What is the InChIKey of 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one?
The InChIKey is LWCZESDRAQTEAT-SZRHLZNOSA-N. The full InChI is InChI=1S/3C22H20N4O.C21H20ClN3O.C21H19F2N3O.C21H23N3O2.C21H21N3O2/c1-22(2)10-9-20-25-19-11-15(5-8-18(19)21(27)26(20)14-22)3-6-17-7-4-16(12-23)13-24-17;1-22(2)9-7-20-25-19-12-15(4-6-18(19)21(27)26(20)14-22)3-5-17-11-16(13-23)8-10-24-17;1-22(2)8-10-26-20(13-22)25-19-12-15(4-6-18(19)21(26)27)3-5-17-11-16(14-23)7-9-24-17;1-21(2)9-8-19-24-18-11-14(6-7-16(18)20(26)25(19)13-21)17(22)12-15-5-3-4-10-23-15;1-14-12-19-25-18-13-15(5-7-16-4-2-3-10-24-16)6-8-17(18)20(27)26(19)11-9-21(14,22)23;1-14(17-6-4-5-11-22-17)26-15-7-8-16-18(12-15)23-19-9-10-21(2,3)13-24(19)20(16)25;1-21(2)9-8-19-23-17-11-14(6-7-15(17)20(26)24(19)13-21)12-18(25)16-5-3-4-10-22-16/h3-8,11,13H,9-10,14H2,1-2H3;3-6,8,10-12H,7,9,14H2,1-2H3;3-7,9,11-12H,8,10,13H2,1-2H3;3-7,10-12H,8-9,13H2,1-2H3;2-8,10,13-14H,9,11-12H2,1H3;4-8,11-12,14H,9-10,13H2,1-3H3;3-7,10-11H,8-9,12-13H2,1-2H3/b6-3+;2*5-3+;17-12-;7-5+;;.
What are the key properties of 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one?
3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one has a molecular weight of 2499.40 g/mol, XLogP of 27.19, 16 rotatable bonds, 0 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[(Z)-1-chloro-2-pyridin-2-ylethenyl]-8,8-dimethyl-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-difluoro-7-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;2-[(E)-2-(7,7-dimethyl-11-oxo-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;2-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-4-carbonitrile;6-[(E)-2-(8,8-dimethyl-11-oxo-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-3-yl)ethenyl]pyridine-3-carbonitrile;8,8-dimethyl-3-(2-oxo-2-pyridin-2-ylethyl)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8,8-dimethyl-3-(1-pyridin-2-ylethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one is sourced from PubChem (CID 159473816), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).