8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one

C167H168F2N26O13 — CID 158023693

About 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one

8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one (PubChem CID 158023693) has the molecular formula C167H168F2N26O13 and a molecular weight of 2785.35 g/mol. Its IUPAC name is 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one.

Molecular Properties

• Compound Name: 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
• PubChem CID: 158023693
• Molecular Formula: C167H168F2N26O13
• Molecular Weight: 2785.35 g/mol
• Exact Mass: 2783.33
• IUPAC Name: 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
• SMILES: CC1(C)CCc2nc3cc(C(=O)Nc4ccccc4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(C(=O)Nc4ccccc4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(C(=O)Nc4ccccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(OCc4ccccn4)ccc3c(=O)n2C1.CC1(C)CCn2c(nc3cc(C(=O)Nc4ccccn4)ccc3c2=O)C1.CC1Cn2c(nc3cc(/C=C/c4ccccn4)ccc3c2=O)CCC1(F)F.Cc1ccc(/C=C/c2ccc3c(=O)n4c(nc3c2)CCC(C)(C)C4)nc1.Cc1ccnc(/C=C/c2ccc3c(=O)n4c(nc3c2)CCC(C)CC4)c1
• InChI: InChI=1S/2C22H23N3O.C21H19F2N3O.2C21H21N3O2.2C20H20N4O2.C20H21N3O2/c1-15-4-7-17(23-13-15)8-5-16-6-9-18-19(12-16)24-20-10-11-22(2,3)14-25(20)21(18)26;1-15-3-8-21-24-20-14-17(4-6-18-13-16(2)9-11-23-18)5-7-19(20)22(26)25(21)12-10-15;1-14-13-26-19(9-10-21(14,22)23)25-18-12-15(6-8-17(18)20(26)27)5-7-16-4-2-3-11-24-16;2*1-21(2)11-10-18-23-17-12-14(8-9-16(17)20(26)24(18)13-21)19(25)22-15-6-4-3-5-7-15;1-20(2)9-8-17-22-15-11-13(6-7-14(15)19(26)24(17)12-20)18(25)23-16-5-3-4-10-21-16;1-20(2)8-10-24-17(12-20)22-15-11-13(6-7-14(15)19(24)26)18(25)23-16-5-3-4-9-21-16;1-20(2)9-8-18-22-17-11-15(25-12-14-5-3-4-10-21-14)6-7-16(17)19(24)23(18)13-20/h4-9,12-13H,10-11,14H2,1-3H3;4-7,9,11,13-15H,3,8,10,12H2,1-2H3;2-8,11-12,14H,9-10,13H2,1H3;2*3-9,12H,10-11,13H2,1-2H3,(H,22,25);3-7,10-11H,8-9,12H2,1-2H3,(H,21,23,25);3-7,9,11H,8,10,12H2,1-2H3,(H,21,23,25);3-7,10-11H,8-9,12-13H2,1-2H3/b8-5+;6-4+;7-5+
• InChIKey: FGIYZSALPOPOSF-UWQXEJPZSA-N
• XLogP: 29.28
• TPSA: 482.09 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 35
• Rotatable Bonds: 17
• Heavy Atoms: 208
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2785.35
LogP ≤ 5	29.28
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one?

The IUPAC name of 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one (CID 158023693) is 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one.

What is the SMILES notation for 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one?

The canonical SMILES for 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one is CC1(C)CCc2nc3cc(C(=O)Nc4ccccc4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(C(=O)Nc4ccccc4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(C(=O)Nc4ccccn4)ccc3c(=O)n2C1.CC1(C)CCc2nc3cc(OCc4ccccn4)ccc3c(=O)n2C1.CC1(C)CCn2c(nc3cc(C(=O)Nc4ccccn4)ccc3c2=O)C1.CC1Cn2c(nc3cc(/C=C/c4ccccn4)ccc3c2=O)CCC1(F)F.Cc1ccc(/C=C/c2ccc3c(=O)n4c(nc3c2)CCC(C)(C)C4)nc1.Cc1ccnc(/C=C/c2ccc3c(=O)n4c(nc3c2)CCC(C)CC4)c1.

What is the InChIKey of 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one?

The InChIKey is FGIYZSALPOPOSF-UWQXEJPZSA-N. The full InChI is InChI=1S/2C22H23N3O.C21H19F2N3O.2C21H21N3O2.2C20H20N4O2.C20H21N3O2/c1-15-4-7-17(23-13-15)8-5-16-6-9-18-19(12-16)24-20-10-11-22(2,3)14-25(20)21(18)26;1-15-3-8-21-24-20-14-17(4-6-18-13-16(2)9-11-23-18)5-7-19(20)22(26)25(21)12-10-15;1-14-13-26-19(9-10-21(14,22)23)25-18-12-15(6-8-17(18)20(26)27)5-7-16-4-2-3-11-24-16;2*1-21(2)11-10-18-23-17-12-14(8-9-16(17)20(26)24(18)13-21)19(25)22-15-6-4-3-5-7-15;1-20(2)9-8-17-22-15-11-13(6-7-14(15)19(26)24(17)12-20)18(25)23-16-5-3-4-10-21-16;1-20(2)8-10-24-17(12-20)22-15-11-13(6-7-14(15)19(24)26)18(25)23-16-5-3-4-9-21-16;1-20(2)9-8-18-22-17-11-15(25-12-14-5-3-4-10-21-14)6-7-16(17)19(24)23(18)13-20/h4-9,12-13H,10-11,14H2,1-3H3;4-7,9,11,13-15H,3,8,10,12H2,1-2H3;2-8,11-12,14H,9-10,13H2,1H3;2*3-9,12H,10-11,13H2,1-2H3,(H,22,25);3-7,10-11H,8-9,12H2,1-2H3,(H,21,23,25);3-7,9,11H,8,10,12H2,1-2H3,(H,21,23,25);3-7,10-11H,8-9,12-13H2,1-2H3/b8-5+;6-4+;7-5+;;;;;.

What are the key properties of 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one?

8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one has a molecular weight of 2785.35 g/mol, XLogP of 29.28, 17 rotatable bonds, 4 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one is sourced from PubChem (CID 158023693), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).