6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one

C150H131F10N15O15 — CID 157271447

IUPAC6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one
SMILESCOc1ccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)cc1C(C)(F)F.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)cc1.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)nc1.Cc1ccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)nc1.Cc1cccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1F.Cc1cccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1.O=C1CCCc2nc(OCc3cccc(F)c3)ccc21
InChIInChI=1S/C25H23F3N2O3.C23H20F2N2O2.2C22H19FN2O2.2C21H18FN3O2.C16H14FNO2/c1-25(27,28)20-13-16(6-8-22(20)32-2)14-30-11-10-21-19(24(30)31)7-9-23(29-21)33-15-17-4-3-5-18(26)12-17;1-15-4-2-6-17(22(15)25)13-27-11-10-20-19(23(27)28)8-9-21(26-20)29-14-16-5-3-7-18(24)12-16;1-15-4-2-7-18(12-15)25-11-10-20-19(22(25)26)8-9-21(24-20)27-14-16-5-3-6-17(23)13-16;1-15-5-8-18(9-6-15)25-12-11-21-20(22(25)26)10-7-17(24-21)14-27-19-4-2-3-16(23)13-19;1-14-5-8-20(23-12-14)25-10-9-19-18(21(25)26)7-6-16(24-19)13-27-17-4-2-3-15(22)11-17;1-14-5-7-19(23-12-14)25-10-9-18-17(21(25)26)6-8-20(24-18)27-13-15-3-2-4-16(22)11-15;17-12-4-1-3-11(9-12)10-20-16-8-7-13-14(18-16)5-2-6-15(13)19/h3-9,12-13H,10-11,14-15H2,1-2H3;2-9,12H,10-11,13-14H2,1H3;2-9,12-13H,10-11,14H2,1H3;2-10,13H,11-12,14H2,1H3;2*2-8,11-12H,9-10,13H2,1H3;1,3-4,7-9H,2,5-6,10H2
InChIKeyAYOXNFAQMLNFPS-UHFFFAOYSA-N
MW2573.77 g/mol
LogP28.92
Rot. Bonds31

About 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one

6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one (PubChem CID 157271447) has the molecular formula C150H131F10N15O15 and a molecular weight of 2573.77 g/mol. Its IUPAC name is 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one.

Molecular Properties

Compound Name6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one
PubChem CID157271447
Molecular FormulaC150H131F10N15O15
Molecular Weight2573.77 g/mol
Exact Mass2571.98
IUPAC Name6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one
SMILESCOc1ccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)cc1C(C)(F)F.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)cc1.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)nc1.Cc1ccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)nc1.Cc1cccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1F.Cc1cccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1.O=C1CCCc2nc(OCc3cccc(F)c3)ccc21
InChIInChI=1S/C25H23F3N2O3.C23H20F2N2O2.2C22H19FN2O2.2C21H18FN3O2.C16H14FNO2/c1-25(27,28)20-13-16(6-8-22(20)32-2)14-30-11-10-21-19(24(30)31)7-9-23(29-21)33-15-17-4-3-5-18(26)12-17;1-15-4-2-6-17(22(15)25)13-27-11-10-20-19(23(27)28)8-9-21(26-20)29-14-16-5-3-7-18(24)12-16;1-15-4-2-7-18(12-15)25-11-10-20-19(22(25)26)8-9-21(24-20)27-14-16-5-3-6-17(23)13-16;1-15-5-8-18(9-6-15)25-12-11-21-20(22(25)26)10-7-17(24-21)14-27-19-4-2-3-16(23)13-19;1-14-5-8-20(23-12-14)25-10-9-19-18(21(25)26)7-6-16(24-19)13-27-17-4-2-3-15(22)11-17;1-14-5-7-19(23-12-14)25-10-9-18-17(21(25)26)6-8-20(24-18)27-13-15-3-2-4-16(22)11-15;17-12-4-1-3-11(9-12)10-20-16-8-7-13-14(18-16)5-2-6-15(13)19/h3-9,12-13H,10-11,14-15H2,1-2H3;2-9,12H,10-11,13-14H2,1H3;2-9,12-13H,10-11,14H2,1H3;2-10,13H,11-12,14H2,1H3;2*2-8,11-12H,9-10,13H2,1H3;1,3-4,7-9H,2,5-6,10H2
InChIKeyAYOXNFAQMLNFPS-UHFFFAOYSA-N
XLogP28.92
TPSA328.78 Ų
H-Bond Donors
H-Bond Acceptors24
Rotatable Bonds31
Heavy Atoms190
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002573.77
LogP ≤ 528.92
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1024

Analyze 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one with MolForge

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Launch Full Analysis

Related Compounds

N-[5-[1-[4-(1-methylpiperidin-4-yl)anilino]-8-oxo-7H-2,7-naphthyridin-3-yl]-2-pyridinyl]acetamide;8-[3-(2-morpholin-4-ylethoxy)anilino]-6-(2,2,2-trifluoroethylamino)-2H-2,7-naphthyridin-1-one
CID 87192323
[5-[6-[4-Methoxy-3-(trifluoromethyl)phenyl]quinazolin-4-yl]pyridin-3-yl]-morpholin-4-ylmethanone
CID 89517263
N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide;N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide;N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide;N-[(1R)-1-[4-oxo-3-[4-(trifluoromethyl)phenyl]quinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide
CID 157683650
8,8-difluoro-9-methyl-3-[(E)-2-pyridin-2-ylethenyl]-6,7,9,10-tetrahydroazepino[2,1-b]quinazolin-12-one;8,8-dimethyl-3-[(E)-2-(5-methyl-2-pyridinyl)ethenyl]-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;bis(8,8-dimethyl-11-oxo-N-phenyl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide);7,7-dimethyl-11-oxo-N-pyridin-2-yl-8,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-11-oxo-N-pyridin-2-yl-7,9-dihydro-6H-pyrido[2,1-b]quinazoline-3-carboxamide;8,8-dimethyl-3-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrido[2,1-b]quinazolin-11-one;8-methyl-3-[(E)-2-(4-methyl-2-pyridinyl)ethenyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-one
CID 158023693
2-[(3-chlorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-(3-fluorophenyl)-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(2-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one
CID 158426548
5-[(4-Fluorophenyl)methyl]-3-(3-hydroxypropyl)-1-methyl-6-(2-propan-2-ylphenoxy)pyrido[2,3-d]pyrimidine-2,4-dione;3-(3-hydroxypropyl)-1-methyl-5-(3-methylbutyl)-6-propan-2-yloxypyrido[2,3-d]pyrimidine-2,4-dione;3-(3-hydroxypropyl)-1-methyl-5-[(4-methylphenyl)methyl]-6-propan-2-yloxypyrido[2,3-d]pyrimidine-2,4-dione;3-(3-hydroxypropyl)-1-methyl-6-[(5-methyl-3-pyridinyl)oxy]-5-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrido[2,3-d]pyrimidine-2,4-dione
CID 158879278
N-(3-chlorophenyl)-6-(phenoxymethyl)pyridine-3-carboxamide;N-[3-(1,1-difluoroethyl)phenyl]-6-(phenoxymethyl)pyridine-3-carboxamide;N-(2,3-difluorophenyl)-6-(phenoxymethyl)pyridine-3-carboxamide;N-(2-fluoro-4-methylphenyl)-6-(phenoxymethyl)pyridine-3-carboxamide;N-(3-fluoro-2-pyridinyl)-6-(phenoxymethyl)pyridine-3-carboxamide;N-(4-methylphenyl)-6-(phenoxymethyl)pyridine-3-carboxamide
CID 159101247
(E)-1-(4-amino-3-fluorophenyl)-5-[5-[5-(4,4-difluoropiperidine-1-carbonyl)-2-pyridinyl]-7-(trifluoromethyl)-1-benzofuran-2-yl]pent-1-en-3-one;(E)-1-(6-amino-3-pyridinyl)-5-[5-[5-(4,4-difluoropiperidine-1-carbonyl)-2-pyridinyl]-3-methyl-7-(trifluoromethyl)-1-benzofuran-2-yl]pent-1-en-3-one;(E)-1-(6-amino-3-pyridinyl)-5-[5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-2-pyridinyl]-7-(trifluoromethyl)-1-benzofuran-2-yl]pent-1-en-3-one;(E)-5-[5-[5-(4,4-difluoropiperidine-1-carbonyl)-2-pyridinyl]-7-pyridin-3-yl-1-benzofuran-2-yl]-1-pyridin-3-ylpent-1-en-3-one;(E)-5-[5-[5-(4,4-difluoropiperidine-1-carbonyl)-2-pyridinyl]-7-pyridin-4-yl-1-benzofuran-2-yl]-1-pyridin-3-ylpent-1-en-3-one
CID 159517319
6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one
CID 159610006
(4-Ethoxy-2-phenyl-1-oxa-9-azaspiro[5.5]undecan-9-yl)-(2-piperidin-1-yl-4-pyridinyl)methanone;(4-ethoxy-2-phenyl-1-oxa-9-azaspiro[5.5]undecan-9-yl)-[4-(2,2,2-trifluoroethoxy)phenyl]methanone;(4-ethoxy-2-phenyl-1-oxa-9-azaspiro[5.5]undecan-9-yl)-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]methanone
CID 160010267
20,20-Dimethyl-16-methylidene-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,26-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10(30),11,13(29),24,27-nonaen-23-one;19,19-dimethyl-23-methylidene-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22-hexazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10(30),11,13(29),24,27-nonaene;20,20-dimethyl-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,26-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10(30),11,13(29),24,27-nonaen-23-one;5-(2,2,2-trifluoroethoxy)-12,17-dioxa-2,4,6,8,25-pentazatricyclo[21.2.2.13,7]octacosa-1(25),3,5,7(28),23,26-hexaen-22-one
CID 160012182
N-benzyl-N-[(1R)-1-[3-[4-(fluoromethyl)phenyl]-4-oxoquinazolin-2-yl]ethyl]-2-[4-(trifluoromethyl)phenyl]acetamide;N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide;N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide;N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide;methane
CID 160453650

Frequently Asked Questions

What is the IUPAC name of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one?
The IUPAC name of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one (CID 157271447) is 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one.
What is the SMILES notation for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one?
The canonical SMILES for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one is COc1ccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)cc1C(C)(F)F.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)cc1.Cc1ccc(N2CCc3nc(COc4cccc(F)c4)ccc3C2=O)nc1.Cc1ccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)nc1.Cc1cccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1F.Cc1cccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)c1.O=C1CCCc2nc(OCc3cccc(F)c3)ccc21.
What is the InChIKey of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one?
The InChIKey is AYOXNFAQMLNFPS-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H23F3N2O3.C23H20F2N2O2.2C22H19FN2O2.2C21H18FN3O2.C16H14FNO2/c1-25(27,28)20-13-16(6-8-22(20)32-2)14-30-11-10-21-19(24(30)31)7-9-23(29-21)33-15-17-4-3-5-18(26)12-17;1-15-4-2-6-17(22(15)25)13-27-11-10-20-19(23(27)28)8-9-21(26-20)29-14-16-5-3-7-18(24)12-16;1-15-4-2-7-18(12-15)25-11-10-20-19(22(25)26)8-9-21(24-20)27-14-16-5-3-6-17(23)13-16;1-15-5-8-18(9-6-15)25-12-11-21-20(22(25)26)10-7-17(24-21)14-27-19-4-2-3-16(23)13-19;1-14-5-8-20(23-12-14)25-10-9-19-18(21(25)26)7-6-16(24-19)13-27-17-4-2-3-15(22)11-17;1-14-5-7-19(23-12-14)25-10-9-18-17(21(25)26)6-8-20(24-18)27-13-15-3-2-4-16(22)11-15;17-12-4-1-3-11(9-12)10-20-16-8-7-13-14(18-16)5-2-6-15(13)19/h3-9,12-13H,10-11,14-15H2,1-2H3;2-9,12H,10-11,13-14H2,1H3;2-9,12-13H,10-11,14H2,1H3;2-10,13H,11-12,14H2,1H3;2*2-8,11-12H,9-10,13H2,1H3;1,3-4,7-9H,2,5-6,10H2.
What are the key properties of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one?
6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one has a molecular weight of 2573.77 g/mol, XLogP of 28.92, 31 rotatable bonds, 0 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;6-[(2-fluoro-3-methylphenyl)methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(4-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenoxy)methyl]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-7,8-dihydro-6H-quinolin-5-one;2-[(3-fluorophenyl)methoxy]-6-(3-methylphenyl)-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one is sourced from PubChem (CID 157271447), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).