6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one

C139H129F5N14O16 — CID 159610006

About 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one

6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one (PubChem CID 159610006) has the molecular formula C139H129F5N14O16 and a molecular weight of 2346.63 g/mol. Its IUPAC name is 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one.

Molecular Properties

• Compound Name: 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one
• PubChem CID: 159610006
• Molecular Formula: C139H129F5N14O16
• Molecular Weight: 2346.63 g/mol
• Exact Mass: 2344.96
• IUPAC Name: 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one
• SMILES: CN1CCc2ncc(COc3cccc(F)c3)cc2C1=O.CN1CCc2ncc(OCc3ccccc3)cc2C1=O.COc1ccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)cc1C(C)(F)F.COc1ccc(CN2CCc3ncc(OCc4ccccc4)cc3C2=O)cc1.Cc1ccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)nc1.Cc1ccc(N2CCc3ncc(OCc4ccccc4)cc3C2=O)cc1.O=C1CCCc2ncc(OCc3ccccc3)cc21
• InChI: InChI=1S/C25H23F3N2O3.C23H22N2O3.C22H20N2O2.C21H18FN3O2.C16H15FN2O2.C16H16N2O2.C16H15NO2/c1-25(27,28)20-13-16(6-8-22(20)32-2)14-30-11-10-21-19(24(30)31)7-9-23(29-21)33-15-17-4-3-5-18(26)12-17;1-27-19-9-7-17(8-10-19)15-25-12-11-22-21(23(25)26)13-20(14-24-22)28-16-18-5-3-2-4-6-18;1-16-7-9-18(10-8-16)24-12-11-21-20(22(24)25)13-19(14-23-21)26-15-17-5-3-2-4-6-17;1-14-5-7-19(23-12-14)25-10-9-18-17(21(25)26)6-8-20(24-18)27-13-15-3-2-4-16(22)11-15;1-19-6-5-15-14(16(19)20)7-11(9-18-15)10-21-13-4-2-3-12(17)8-13;1-18-8-7-15-14(16(18)19)9-13(10-17-15)20-11-12-5-3-2-4-6-12;18-16-8-4-7-15-14(16)9-13(10-17-15)19-11-12-5-2-1-3-6-12/h3-9,12-13H,10-11,14-15H2,1-2H3;2-10,13-14H,11-12,15-16H2,1H3;2-10,13-14H,11-12,15H2,1H3;2-8,11-12H,9-10,13H2,1H3;2-4,7-9H,5-6,10H2,1H3;2-6,9-10H,7-8,11H2,1H3;1-3,5-6,9-10H,4,7-8,11H2
• InChIKey: MMOKDKMMQYTFDB-UHFFFAOYSA-N
• XLogP: 24.76
• TPSA: 325.12 Ų
• H-Bond Acceptors: 24
• Rotatable Bonds: 30
• Heavy Atoms: 174
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2346.63
LogP ≤ 5	24.76
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one?

The IUPAC name of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one (CID 159610006) is 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one.

What is the SMILES notation for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one?

The canonical SMILES for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one is CN1CCc2ncc(COc3cccc(F)c3)cc2C1=O.CN1CCc2ncc(OCc3ccccc3)cc2C1=O.COc1ccc(CN2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)cc1C(C)(F)F.COc1ccc(CN2CCc3ncc(OCc4ccccc4)cc3C2=O)cc1.Cc1ccc(N2CCc3nc(OCc4cccc(F)c4)ccc3C2=O)nc1.Cc1ccc(N2CCc3ncc(OCc4ccccc4)cc3C2=O)cc1.O=C1CCCc2ncc(OCc3ccccc3)cc21.

What is the InChIKey of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one?

The InChIKey is MMOKDKMMQYTFDB-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H23F3N2O3.C23H22N2O3.C22H20N2O2.C21H18FN3O2.C16H15FN2O2.C16H16N2O2.C16H15NO2/c1-25(27,28)20-13-16(6-8-22(20)32-2)14-30-11-10-21-19(24(30)31)7-9-23(29-21)33-15-17-4-3-5-18(26)12-17;1-27-19-9-7-17(8-10-19)15-25-12-11-22-21(23(25)26)13-20(14-24-22)28-16-18-5-3-2-4-6-18;1-16-7-9-18(10-8-16)24-12-11-21-20(22(24)25)13-19(14-23-21)26-15-17-5-3-2-4-6-17;1-14-5-7-19(23-12-14)25-10-9-18-17(21(25)26)6-8-20(24-18)27-13-15-3-2-4-16(22)11-15;1-19-6-5-15-14(16(19)20)7-11(9-18-15)10-21-13-4-2-3-12(17)8-13;1-18-8-7-15-14(16(18)19)9-13(10-17-15)20-11-12-5-3-2-4-6-12;18-16-8-4-7-15-14(16)9-13(10-17-15)19-11-12-5-2-1-3-6-12/h3-9,12-13H,10-11,14-15H2,1-2H3;2-10,13-14H,11-12,15-16H2,1H3;2-10,13-14H,11-12,15H2,1H3;2-8,11-12H,9-10,13H2,1H3;2-4,7-9H,5-6,10H2,1H3;2-6,9-10H,7-8,11H2,1H3;1-3,5-6,9-10H,4,7-8,11H2.

What are the key properties of 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one?

6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one has a molecular weight of 2346.63 g/mol, XLogP of 24.76, 30 rotatable bonds, 0 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[[3-(1,1-difluoroethyl)-4-methoxyphenyl]methyl]-2-[(3-fluorophenyl)methoxy]-7,8-dihydro-1,6-naphthyridin-5-one;3-[(3-fluorophenoxy)methyl]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one;2-[(3-fluorophenyl)methoxy]-6-(5-methyl-2-pyridinyl)-7,8-dihydro-1,6-naphthyridin-5-one;6-[(4-methoxyphenyl)methyl]-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-methyl-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;6-(4-methylphenyl)-3-phenylmethoxy-7,8-dihydro-1,6-naphthyridin-5-one;3-phenylmethoxy-7,8-dihydro-6H-quinolin-5-one is sourced from PubChem (CID 159610006), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).