7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide

C120H106F2N22O10 — CID 159499455

IUPAC7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide
SMILESCOc1ccc(-c2cc(C(N)=O)nc3cc(C(C)Cc4cnc(C#N)nc4)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cnc(C)nc4)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cncnc4N)ccc23)cc1
InChIInChI=1S/C25H21N5O2.2C24H21FN4O2.C24H22N4O2.C23H21N5O2/c1-15(9-16-13-28-24(12-26)29-14-16)18-5-8-20-21(17-3-6-19(32-2)7-4-17)11-23(25(27)31)30-22(20)10-18;1-14-27-12-16(13-28-14)4-3-15-5-7-19-20(11-23(24(26)30)29-22(19)9-15)18-8-6-17(31-2)10-21(18)25;1-31-16-7-9-17(20(25)12-16)19-13-22(24(27)30)29-21-11-14(5-8-18(19)21)4-6-15-3-2-10-28-23(15)26;1-30-18-9-7-16(8-10-18)20-14-22(24(26)29)28-21-13-15(5-11-19(20)21)4-6-17-3-2-12-27-23(17)25;1-30-17-7-5-15(6-8-17)19-11-21(23(25)29)28-20-10-14(3-9-18(19)20)2-4-16-12-26-13-27-22(16)24/h3-8,10-11,13-15H,9H2,1-2H3,(H2,27,31);5-13H,3-4H2,1-2H3,(H2,26,30);2-3,5,7-13H,4,6H2,1H3,(H2,26,28)(H2,27,30);2-3,5,7-14H,4,6H2,1H3,(H2,25,27)(H2,26,29);3,5-13H,2,4H2,1H3,(H2,25,29)(H2,24,26,27)
InChIKeyLZEUUZLHRUGUMS-UHFFFAOYSA-N
MW2054.31 g/mol
LogP18.90
Rot. Bonds30

About 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide

7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide (PubChem CID 159499455) has the molecular formula C120H106F2N22O10 and a molecular weight of 2054.31 g/mol. Its IUPAC name is 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide.

Molecular Properties

Compound Name7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide
PubChem CID159499455
Molecular FormulaC120H106F2N22O10
Molecular Weight2054.31 g/mol
Exact Mass2052.84
IUPAC Name7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide
SMILESCOc1ccc(-c2cc(C(N)=O)nc3cc(C(C)Cc4cnc(C#N)nc4)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cnc(C)nc4)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cncnc4N)ccc23)cc1
InChIInChI=1S/C25H21N5O2.2C24H21FN4O2.C24H22N4O2.C23H21N5O2/c1-15(9-16-13-28-24(12-26)29-14-16)18-5-8-20-21(17-3-6-19(32-2)7-4-17)11-23(25(27)31)30-22(20)10-18;1-14-27-12-16(13-28-14)4-3-15-5-7-19-20(11-23(24(26)30)29-22(19)9-15)18-8-6-17(31-2)10-21(18)25;1-31-16-7-9-17(20(25)12-16)19-13-22(24(27)30)29-21-11-14(5-8-18(19)21)4-6-15-3-2-10-28-23(15)26;1-30-18-9-7-16(8-10-18)20-14-22(24(26)29)28-21-13-15(5-11-19(20)21)4-6-17-3-2-12-27-23(17)25;1-30-17-7-5-15(6-8-17)19-11-21(23(25)29)28-20-10-14(3-9-18(19)20)2-4-16-12-26-13-27-22(16)24/h3-8,10-11,13-15H,9H2,1-2H3,(H2,27,31);5-13H,3-4H2,1-2H3,(H2,26,30);2-3,5,7-13H,4,6H2,1H3,(H2,26,28)(H2,27,30);2-3,5,7-14H,4,6H2,1H3,(H2,25,27)(H2,26,29);3,5-13H,2,4H2,1H3,(H2,25,29)(H2,24,26,27)
InChIKeyLZEUUZLHRUGUMS-UHFFFAOYSA-N
XLogP18.90
TPSA531.02 Ų
H-Bond Donors8
H-Bond Acceptors27
Rotatable Bonds30
Heavy Atoms154
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002054.31
LogP ≤ 518.90
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1027

Analyze 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

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Related Compounds

(4-(2-Fluoro-4-methylphenyl)-5-(4-methoxyphenyl)pyrimidin-2-yl)(4-(quinolin-3-yl)piperazin-1-yl)methanone
CID 54583296
4-(4-Methoxyphenyl)-7-(2-(2-methylpyrimidin-5-yl)ethyl)quinoline-2-carboxamide
CID 89554797
4-(3-Fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide
CID 89554872
4-(2-Fluoro-4-methoxyphenyl)-7-(2-(2-methylpyrimidin-5-yl)ethyl)quinoline-2-carboxamide
CID 89554892
US8653087, III-413
CID 68036201
US8653087, III-562
CID 68036210
US8653087, III-554
CID 46181821
US8653087, III-415
CID 68036197
US8653087, III-556
CID 68036384
US8653087, III-557
CID 68036385
4-(2-Fluoro-4-methoxyphenyl)-7-[1-(2-methylpyrimidin-5-yl)propan-2-yl]quinoline-2-carboxamide
CID 71565966
7-(1-(2-Aminopyridin-3-yl)propan-2-yl)-4-(4-methoxyphenyl)quinoline-2-carboxamide
CID 71566048

Frequently Asked Questions

What is the IUPAC name of 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide?
The IUPAC name of 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide (CID 159499455) is 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide.
What is the SMILES notation for 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide?
The canonical SMILES for 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide is COc1ccc(-c2cc(C(N)=O)nc3cc(C(C)Cc4cnc(C#N)nc4)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cccnc4N)ccc23)cc1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cnc(C)nc4)ccc23)c(F)c1.COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cncnc4N)ccc23)cc1.
What is the InChIKey of 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide?
The InChIKey is LZEUUZLHRUGUMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H21N5O2.2C24H21FN4O2.C24H22N4O2.C23H21N5O2/c1-15(9-16-13-28-24(12-26)29-14-16)18-5-8-20-21(17-3-6-19(32-2)7-4-17)11-23(25(27)31)30-22(20)10-18;1-14-27-12-16(13-28-14)4-3-15-5-7-19-20(11-23(24(26)30)29-22(19)9-15)18-8-6-17(31-2)10-21(18)25;1-31-16-7-9-17(20(25)12-16)19-13-22(24(27)30)29-21-11-14(5-8-18(19)21)4-6-15-3-2-10-28-23(15)26;1-30-18-9-7-16(8-10-18)20-14-22(24(26)29)28-21-13-15(5-11-19(20)21)4-6-17-3-2-12-27-23(17)25;1-30-17-7-5-15(6-8-17)19-11-21(23(25)29)28-20-10-14(3-9-18(19)20)2-4-16-12-26-13-27-22(16)24/h3-8,10-11,13-15H,9H2,1-2H3,(H2,27,31);5-13H,3-4H2,1-2H3,(H2,26,30);2-3,5,7-13H,4,6H2,1H3,(H2,26,28)(H2,27,30);2-3,5,7-14H,4,6H2,1H3,(H2,25,27)(H2,26,29);3,5-13H,2,4H2,1H3,(H2,25,29)(H2,24,26,27).
What are the key properties of 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide?
7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide has a molecular weight of 2054.31 g/mol, XLogP of 18.90, 30 rotatable bonds, 8 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 7-[2-(2-amino-3-pyridinyl)ethyl]-4-(2-fluoro-4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(2-amino-3-pyridinyl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[2-(4-aminopyrimidin-5-yl)ethyl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;7-[1-(2-cyanopyrimidin-5-yl)propan-2-yl]-4-(4-methoxyphenyl)quinoline-2-carboxamide;4-(2-fluoro-4-methoxyphenyl)-7-[2-(2-methylpyrimidin-5-yl)ethyl]quinoline-2-carboxamide is sourced from PubChem (CID 159499455), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).