6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one

C101H121F15N32O13 — CID 159503480

IUPAC6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one
SMILESCN(C)C(=O)C1CN(c2cc(-c3cnc(N)cc3C(F)(F)F)nc(N3CCOCC3)n2)CCO1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(=O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCOC(C(=O)N4CCOCC4)C3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(NC3CCOCC3)nc(N3CCOCC3)n2)cn1
InChIInChI=1S/C23H28F3N7O4.C21H26F3N7O3.2C19H23F3N6O2.C19H21F3N6O2/c24-23(25,26)16-11-19(27)28-13-15(16)17-12-20(30-22(29-17)32-3-8-36-9-4-32)33-5-10-37-18(14-33)21(34)31-1-6-35-7-2-31;1-29(2)19(32)16-12-31(5-8-34-16)18-10-15(27-20(28-18)30-3-6-33-7-4-30)13-11-26-17(25)9-14(13)21(22,23)24;20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(25-12-1-5-29-6-2-12)27-18(26-15)28-3-7-30-8-4-28;2*20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(27-3-1-12(29)2-4-27)26-18(25-15)28-5-7-30-8-6-28/h11-13,18H,1-10,14H2,(H2,27,28);9-11,16H,3-8,12H2,1-2H3,(H2,25,26);9-12H,1-8H2,(H2,23,24)(H,25,26,27);9-12,29H,1-8H2,(H2,23,24);9-11H,1-8H2,(H2,23,24)
InChIKeyLZRKEUQRYJIENB-UHFFFAOYSA-N
MW2276.26 g/mol
LogP8.96
Rot. Bonds18

About 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one

6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one (PubChem CID 159503480) has the molecular formula C101H121F15N32O13 and a molecular weight of 2276.26 g/mol. Its IUPAC name is 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one.

Molecular Properties

Compound Name6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one
PubChem CID159503480
Molecular FormulaC101H121F15N32O13
Molecular Weight2276.26 g/mol
Exact Mass2274.96
IUPAC Name6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one
SMILESCN(C)C(=O)C1CN(c2cc(-c3cnc(N)cc3C(F)(F)F)nc(N3CCOCC3)n2)CCO1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(=O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCOC(C(=O)N4CCOCC4)C3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(NC3CCOCC3)nc(N3CCOCC3)n2)cn1
InChIInChI=1S/C23H28F3N7O4.C21H26F3N7O3.2C19H23F3N6O2.C19H21F3N6O2/c24-23(25,26)16-11-19(27)28-13-15(16)17-12-20(30-22(29-17)32-3-8-36-9-4-32)33-5-10-37-18(14-33)21(34)31-1-6-35-7-2-31;1-29(2)19(32)16-12-31(5-8-34-16)18-10-15(27-20(28-18)30-3-6-33-7-4-30)13-11-26-17(25)9-14(13)21(22,23)24;20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(25-12-1-5-29-6-2-12)27-18(26-15)28-3-7-30-8-4-28;2*20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(27-3-1-12(29)2-4-27)26-18(25-15)28-5-7-30-8-6-28/h11-13,18H,1-10,14H2,(H2,27,28);9-11,16H,3-8,12H2,1-2H3,(H2,25,26);9-12H,1-8H2,(H2,23,24)(H,25,26,27);9-12,29H,1-8H2,(H2,23,24);9-11H,1-8H2,(H2,23,24)
InChIKeyLZRKEUQRYJIENB-UHFFFAOYSA-N
XLogP8.96
TPSA525.63 Ų
H-Bond Donors7
H-Bond Acceptors43
Rotatable Bonds18
Heavy Atoms161
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002276.26
LogP ≤ 58.96
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1043

Analyze 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine;methane
CID 144743484
5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-carboxamide
CID 151222565
5-[6-[(2S,6R)-2-ethyl-6-methylmorpholin-4-yl]-2-morpholin-4-ylpyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
CID 162557599
1-[5-[[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]amino]-2-pyridinyl]ethane-1,1-diol
CID 70848217
5-[6-[3-(4-fluorophenyl)morpholin-4-yl]-2-morpholin-4-ylpyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
CID 59507849
5-(6-tert-butyl-2-morpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
CID 145100358
6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[4-(1-propan-2-ylpiperidin-4-yl)oxyphenyl]pyrimidin-4-amine
CID 59507494
5-[2-morpholin-4-yl-6-(3-phenylmorpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
CID 59507653
5-(2-morpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
CID 59507833
N-[2-[[5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)-2-pyridinyl]amino]-2-oxoethyl]icosa-5,8,11,14,17-pentaenamide
CID 123997428
5-[6-(1-methylcyclopropyl)-2-morpholin-4-ylpyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
CID 121428557
2-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N-tert-butylbenzenesulfonamide
CID 59507814

Frequently Asked Questions

What is the IUPAC name of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one?
The IUPAC name of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one (CID 159503480) is 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one.
What is the SMILES notation for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one?
The canonical SMILES for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one is CN(C)C(=O)C1CN(c2cc(-c3cnc(N)cc3C(F)(F)F)nc(N3CCOCC3)n2)CCO1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(=O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCC(O)CC3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(N3CCOC(C(=O)N4CCOCC4)C3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(NC3CCOCC3)nc(N3CCOCC3)n2)cn1.
What is the InChIKey of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one?
The InChIKey is LZRKEUQRYJIENB-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H28F3N7O4.C21H26F3N7O3.2C19H23F3N6O2.C19H21F3N6O2/c24-23(25,26)16-11-19(27)28-13-15(16)17-12-20(30-22(29-17)32-3-8-36-9-4-32)33-5-10-37-18(14-33)21(34)31-1-6-35-7-2-31;1-29(2)19(32)16-12-31(5-8-34-16)18-10-15(27-20(28-18)30-3-6-33-7-4-30)13-11-26-17(25)9-14(13)21(22,23)24;20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(25-12-1-5-29-6-2-12)27-18(26-15)28-3-7-30-8-4-28;2*20-19(21,22)14-9-16(23)24-11-13(14)15-10-17(27-3-1-12(29)2-4-27)26-18(25-15)28-5-7-30-8-6-28/h11-13,18H,1-10,14H2,(H2,27,28);9-11,16H,3-8,12H2,1-2H3,(H2,25,26);9-12H,1-8H2,(H2,23,24)(H,25,26,27);9-12,29H,1-8H2,(H2,23,24);9-11H,1-8H2,(H2,23,24).
What are the key properties of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one?
6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one has a molecular weight of 2276.26 g/mol, XLogP of 8.96, 18 rotatable bonds, 7 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-(oxan-4-yl)pyrimidin-4-amine;4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]-N,N-dimethylmorpholine-2-carboxamide;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]morpholin-2-yl]-morpholin-4-ylmethanone;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-ol;1-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]piperidin-4-one is sourced from PubChem (CID 159503480), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).