6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine

C94H62Cl2F22N26O2 — CID 159636430

About 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine

6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine (PubChem CID 159636430) has the molecular formula C94H62Cl2F22N26O2 and a molecular weight of 2076.57 g/mol. Its IUPAC name is 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine.

Molecular Properties

• Compound Name: 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine
• PubChem CID: 159636430
• Molecular Formula: C94H62Cl2F22N26O2
• Molecular Weight: 2076.57 g/mol
• Exact Mass: 2074.46
• IUPAC Name: 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine
• SMILES: Cc1nc2c(F)cc(F)cc2n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ncc(Cl)cc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cn1nc2ccc(F)cc2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.ONc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccc(F)cn23)c1
• InChI: InChI=1S/C20H12ClF3N6.C20H12F7N5O.C19H12F5N5.C19H13F4N5.C16H13ClF3N5O/c1-11-27-19-16(8-14(21)10-26-19)30(11)18-7-12(9-25)6-17(29-18)28-15-4-2-13(3-5-15)20(22,23)24;21-11-3-6-16-30-18(20(25,26)27)17(32(16)9-11)14-7-13(31-33)8-15(29-14)28-12-4-1-10(2-5-12)19(22,23)24;1-10-26-18-14(21)6-12(20)7-15(18)29(10)17-9-25-8-16(28-17)27-13-4-2-11(3-5-13)19(22,23)24;1-28-18(14-8-12(20)4-7-15(14)27-28)16-9-24-10-17(26-16)25-13-5-2-11(3-6-13)19(21,22)23;1-8-14(15(17)25(2)24-8)11-6-21-7-13(23-11)22-9-3-4-12(10(18)5-9)26-16(19)20/h2-8,10H,1H3,(H,28,29);1-9,33H,(H2,28,29,31);2-9H,1H3,(H,27,28);2-10H,1H3,(H,25,26);3-7,16H,1-2H3,(H,22,23)
• InChIKey: MPUNTFGCYWVRGE-UHFFFAOYSA-N
• XLogP: 25.95
• TPSA: 330.02 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 28
• Rotatable Bonds: 18
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2076.57
LogP ≤ 5	25.95
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine?

The IUPAC name of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine (CID 159636430) is 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine.

What is the SMILES notation for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine?

The canonical SMILES for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine is Cc1nc2c(F)cc(F)cc2n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ncc(Cl)cc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cn1nc2ccc(F)cc2c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.ONc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(F)(F)F)nc3ccc(F)cn23)c1.

What is the InChIKey of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine?

The InChIKey is MPUNTFGCYWVRGE-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H12ClF3N6.C20H12F7N5O.C19H12F5N5.C19H13F4N5.C16H13ClF3N5O/c1-11-27-19-16(8-14(21)10-26-19)30(11)18-7-12(9-25)6-17(29-18)28-15-4-2-13(3-5-15)20(22,23)24;21-11-3-6-16-30-18(20(25,26)27)17(32(16)9-11)14-7-13(31-33)8-15(29-14)28-12-4-1-10(2-5-12)19(22,23)24;1-10-26-18-14(21)6-12(20)7-15(18)29(10)17-9-25-8-16(28-17)27-13-4-2-11(3-5-13)19(22,23)24;1-28-18(14-8-12(20)4-7-15(14)27-28)16-9-24-10-17(26-16)25-13-5-2-11(3-6-13)19(21,22)23;1-8-14(15(17)25(2)24-8)11-6-21-7-13(23-11)22-9-3-4-12(10(18)5-9)26-16(19)20/h2-8,10H,1H3,(H,28,29);1-9,33H,(H2,28,29,31);2-9H,1H3,(H,27,28);2-10H,1H3,(H,25,26);3-7,16H,1-2H3,(H,22,23).

What are the key properties of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine?

6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine has a molecular weight of 2076.57 g/mol, XLogP of 25.95, 18 rotatable bonds, 7 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)-3-fluorophenyl]pyrazin-2-amine;2-(6-chloro-2-methylimidazo[4,5-b]pyridin-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(4,6-difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(5-fluoro-2-methylindazol-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[2-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-6-[4-(trifluoromethyl)anilino]-4-pyridinyl]hydroxylamine is sourced from PubChem (CID 159636430), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).