N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide

C107H120N24O21S5 — CID 159667614

About N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide

N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide (PubChem CID 159667614) has the molecular formula C107H120N24O21S5 and a molecular weight of 2238.62 g/mol. Its IUPAC name is N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide
• PubChem CID: 159667614
• Molecular Formula: C107H120N24O21S5
• Molecular Weight: 2238.62 g/mol
• Exact Mass: 2236.77
• IUPAC Name: N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide
• SMILES: O=C(NO)c1ccc(NC2CCCN(S(=O)(=O)c3ccc4c(c3)CCCC4)CC2)nc1.O=C(NO)c1cnc(NC2CCCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)nc1.O=C(NO)c1cnc(NC2CCCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CN(S(=O)(=O)c3ccc4ccccc4c3)CCO2)nc1
• InChI: InChI=1S/C23H25N5O4S.C22H28N4O4S.2C21H23N5O4S.C20H21N5O5S/c29-22(27-30)19-15-24-23(25-16-19)26-20-7-4-13-28(14-12-20)33(31,32)21-10-8-18(9-11-21)17-5-2-1-3-6-17;27-22(25-28)18-8-10-21(23-15-18)24-19-6-3-12-26(13-11-19)31(29,30)20-9-7-16-4-1-2-5-17(16)14-20;27-20(25-28)17-13-22-21(23-14-17)24-18-6-3-10-26(11-9-18)31(29,30)19-8-7-15-4-1-2-5-16(15)12-19;27-20(25-28)18-13-23-21(24-14-18)22-12-15-7-9-26(10-8-15)31(29,30)19-6-5-16-3-1-2-4-17(16)11-19;26-19(24-27)16-10-21-20(22-11-16)23-12-17-13-25(7-8-30-17)31(28,29)18-6-5-14-3-1-2-4-15(14)9-18/h1-3,5-6,8-11,15-16,20,30H,4,7,12-14H2,(H,27,29)(H,24,25,26);7-10,14-15,19,28H,1-6,11-13H2,(H,23,24)(H,25,27);1-2,4-5,7-8,12-14,18,28H,3,6,9-11H2,(H,25,27)(H,22,23,24);1-6,11,13-15,28H,7-10,12H2,(H,25,27)(H,22,23,24);1-6,9-11,17,27H,7-8,12-13H2,(H,24,26)(H,21,22,23)
• InChIKey: MTPNTLGEKGGCKW-UHFFFAOYSA-N
• XLogP: 11.57
• TPSA: 618.94 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 35
• Rotatable Bonds: 28
• Heavy Atoms: 157
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2238.62
LogP ≤ 5	11.57
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	35

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide?

The IUPAC name of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide (CID 159667614) is N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide.

What is the SMILES notation for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide?

The canonical SMILES for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide is O=C(NO)c1ccc(NC2CCCN(S(=O)(=O)c3ccc4c(c3)CCCC4)CC2)nc1.O=C(NO)c1cnc(NC2CCCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)nc1.O=C(NO)c1cnc(NC2CCCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CN(S(=O)(=O)c3ccc4ccccc4c3)CCO2)nc1.

What is the InChIKey of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide?

The InChIKey is MTPNTLGEKGGCKW-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25N5O4S.C22H28N4O4S.2C21H23N5O4S.C20H21N5O5S/c29-22(27-30)19-15-24-23(25-16-19)26-20-7-4-13-28(14-12-20)33(31,32)21-10-8-18(9-11-21)17-5-2-1-3-6-17;27-22(25-28)18-8-10-21(23-15-18)24-19-6-3-12-26(13-11-19)31(29,30)20-9-7-16-4-1-2-5-17(16)14-20;27-20(25-28)17-13-22-21(23-14-17)24-18-6-3-10-26(11-9-18)31(29,30)19-8-7-15-4-1-2-5-16(15)12-19;27-20(25-28)18-13-23-21(24-14-18)22-12-15-7-9-26(10-8-15)31(29,30)19-6-5-16-3-1-2-4-17(16)11-19;26-19(24-27)16-10-21-20(22-11-16)23-12-17-13-25(7-8-30-17)31(28,29)18-6-5-14-3-1-2-4-15(14)9-18/h1-3,5-6,8-11,15-16,20,30H,4,7,12-14H2,(H,27,29)(H,24,25,26);7-10,14-15,19,28H,1-6,11-13H2,(H,23,24)(H,25,27);1-2,4-5,7-8,12-14,18,28H,3,6,9-11H2,(H,25,27)(H,22,23,24);1-6,11,13-15,28H,7-10,12H2,(H,25,27)(H,22,23,24);1-6,9-11,17,27H,7-8,12-13H2,(H,24,26)(H,21,22,23).

What are the key properties of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide?

N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide has a molecular weight of 2238.62 g/mol, XLogP of 11.57, 28 rotatable bonds, 15 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-6-[[1-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)azepan-4-yl]amino]pyridine-3-carboxamide is sourced from PubChem (CID 159667614), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).