1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

C113H134F6N18O7 — CID 159674882

About 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (PubChem CID 159674882) has the molecular formula C113H134F6N18O7 and a molecular weight of 1970.42 g/mol. Its IUPAC name is 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

Molecular Properties

• Compound Name: 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
• PubChem CID: 159674882
• Molecular Formula: C113H134F6N18O7
• Molecular Weight: 1970.42 g/mol
• Exact Mass: 1969.06
• IUPAC Name: 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
• SMILES: CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C(F)(F)F)cc2ccccc12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(C3CC3)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(OC(F)(F)F)cccn12.Cc1cc2c(C)nccc2c(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)n1.Cc1cccn2c(C3(NC(=O)C4[C@H]5CNC[C@@H]45)CC3)ncc12.Cc1nc2ccccn2c1C(C)(C)CC(=O)C1[C@H]2CNC[C@@H]12
• InChI: InChI=1S/C20H21F3N2O.2C20H25N3O.C18H20F3N3O2.C18H23N3O.C17H20N4O/c1-19(2,8-15(26)17-13-9-24-10-14(13)17)18-12-6-4-3-5-11(12)7-16(25-18)20(21,22)23;1-20(2,8-17(24)18-14-9-21-10-15(14)18)19-22-11-16-13(12-5-6-12)4-3-7-23(16)19;1-11-7-14-12(2)22-6-5-13(14)19(23-11)20(3,4)8-17(24)18-15-9-21-10-16(15)18;1-17(2,6-13(25)15-10-7-22-8-11(10)15)16-23-9-12-14(26-18(19,20)21)4-3-5-24(12)16;1-11-17(21-7-5-4-6-15(21)20-11)18(2,3)8-14(22)16-12-9-19-10-13(12)16;1-10-3-2-6-21-13(10)9-19-16(21)17(4-5-17)20-15(22)14-11-7-18-8-12(11)14/h3-7,13-14,17,24H,8-10H2,1-2H3;3-4,7,11-12,14-15,18,21H,5-6,8-10H2,1-2H3;5-7,15-16,18,21H,8-10H2,1-4H3;3-5,9-11,15,22H,6-8H2,1-2H3;4-7,12-13,16,19H,8-10H2,1-3H3;2-3,6,9,11-12,14,18H,4-5,7-8H2,1H3,(H,20,22)/t13-,14+,17?;14-,15+,18?;15-,16+,18?;10-,11+,15?;12-,13+,16?;11-,12+,14?
• InChIKey: MULXUPNUWXCCCB-QFPUAGBISA-N
• XLogP: 16.31
• TPSA: 303.73 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 24
• Rotatable Bonds: 25
• Heavy Atoms: 144
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1970.42
LogP ≤ 5	16.31
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The IUPAC name of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (CID 159674882) is 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

What is the SMILES notation for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The canonical SMILES for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C(F)(F)F)cc2ccccc12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(C3CC3)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(OC(F)(F)F)cccn12.Cc1cc2c(C)nccc2c(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)n1.Cc1cccn2c(C3(NC(=O)C4[C@H]5CNC[C@@H]45)CC3)ncc12.Cc1nc2ccccn2c1C(C)(C)CC(=O)C1[C@H]2CNC[C@@H]12.

What is the InChIKey of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The InChIKey is MULXUPNUWXCCCB-QFPUAGBISA-N. The full InChI is InChI=1S/C20H21F3N2O.2C20H25N3O.C18H20F3N3O2.C18H23N3O.C17H20N4O/c1-19(2,8-15(26)17-13-9-24-10-14(13)17)18-12-6-4-3-5-11(12)7-16(25-18)20(21,22)23;1-20(2,8-17(24)18-14-9-21-10-15(14)18)19-22-11-16-13(12-5-6-12)4-3-7-23(16)19;1-11-7-14-12(2)22-6-5-13(14)19(23-11)20(3,4)8-17(24)18-15-9-21-10-16(15)18;1-17(2,6-13(25)15-10-7-22-8-11(10)15)16-23-9-12-14(26-18(19,20)21)4-3-5-24(12)16;1-11-17(21-7-5-4-6-15(21)20-11)18(2,3)8-14(22)16-12-9-19-10-13(12)16;1-10-3-2-6-21-13(10)9-19-16(21)17(4-5-17)20-15(22)14-11-7-18-8-12(11)14/h3-7,13-14,17,24H,8-10H2,1-2H3;3-4,7,11-12,14-15,18,21H,5-6,8-10H2,1-2H3;5-7,15-16,18,21H,8-10H2,1-4H3;3-5,9-11,15,22H,6-8H2,1-2H3;4-7,12-13,16,19H,8-10H2,1-3H3;2-3,6,9,11-12,14,18H,4-5,7-8H2,1H3,(H,20,22)/t13-,14+,17?;14-,15+,18?;15-,16+,18?;10-,11+,15?;12-,13+,16?;11-,12+,14?.

What are the key properties of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide has a molecular weight of 1970.42 g/mol, XLogP of 16.31, 25 rotatable bonds, 7 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is sourced from PubChem (CID 159674882), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).