1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one

C112H136F4N18O7 — CID 162095937

IUPAC1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one
SMILESCC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(C3CC3)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(OC(F)(F)F)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1nc2ccccn2c1C(C)(C)CC(=O)C1[C@H]2CNC[C@@H]12
InChIInChI=1S/2C20H25N3O.C18H20F3N3O2.C18H20FN3O.2C18H23N3O/c1-20(2,8-17(24)18-14-9-21-10-15(14)18)19-22-11-16-13(12-5-6-12)4-3-7-23(16)19;1-11-6-5-7-13-18(11)22-12(2)23-19(13)20(3,4)8-16(24)17-14-9-21-10-15(14)17;1-17(2,6-13(25)15-10-7-22-8-11(10)15)16-23-9-12-14(26-18(19,20)21)4-3-5-24(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-11-17(21-7-5-4-6-15(21)20-11)18(2,3)8-14(22)16-12-9-19-10-13(12)16;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h3-4,7,11-12,14-15,18,21H,5-6,8-10H2,1-2H3;5-7,14-15,17,21H,8-10H2,1-4H3;3-5,9-11,15,22H,6-8H2,1-2H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;2*4-7,12-13,16,19H,8-10H2,1-3H3/t14-,15+,18?;14-,15+,17?;10-,11+,15?;11-,12+,15?;2*12-,13+,16?
InChIKeyZEFZWCADDKCOFW-ASDFBCLJSA-N
MW1922.43 g/mol
LogP15.96
Rot. Bonds26

About 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one

1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one (PubChem CID 162095937) has the molecular formula C112H136F4N18O7 and a molecular weight of 1922.43 g/mol. Its IUPAC name is 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one.

Molecular Properties

Compound Name1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one
PubChem CID162095937
Molecular FormulaC112H136F4N18O7
Molecular Weight1922.43 g/mol
Exact Mass1921.08
IUPAC Name1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one
SMILESCC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(C3CC3)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(OC(F)(F)F)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1nc2ccccn2c1C(C)(C)CC(=O)C1[C@H]2CNC[C@@H]12
InChIInChI=1S/2C20H25N3O.C18H20F3N3O2.C18H20FN3O.2C18H23N3O/c1-20(2,8-17(24)18-14-9-21-10-15(14)18)19-22-11-16-13(12-5-6-12)4-3-7-23(16)19;1-11-6-5-7-13-18(11)22-12(2)23-19(13)20(3,4)8-16(24)17-14-9-21-10-15(14)17;1-17(2,6-13(25)15-10-7-22-8-11(10)15)16-23-9-12-14(26-18(19,20)21)4-3-5-24(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-11-17(21-7-5-4-6-15(21)20-11)18(2,3)8-14(22)16-12-9-19-10-13(12)16;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h3-4,7,11-12,14-15,18,21H,5-6,8-10H2,1-2H3;5-7,14-15,17,21H,8-10H2,1-4H3;3-5,9-11,15,22H,6-8H2,1-2H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;2*4-7,12-13,16,19H,8-10H2,1-3H3/t14-,15+,18?;14-,15+,17?;10-,11+,15?;11-,12+,15?;2*12-,13+,16?
InChIKeyZEFZWCADDKCOFW-ASDFBCLJSA-N
XLogP15.96
TPSA304.59 Ų
H-Bond Donors6
H-Bond Acceptors25
Rotatable Bonds26
Heavy Atoms141
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001922.43
LogP ≤ 515.96
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1025

Analyze 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one with MolForge

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Launch Full Analysis

Related Compounds

CID 157209221
CID 157209221
(1S,5R)-N-[1-(2-ethylphenoxy)-2-methylpropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-(3-methylpyrazin-2-yl)oxypropan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(4-methyl-3-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(2-methylquinolin-4-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 158599699
(1R,5S)-N-[2-methyl-4-(3-methylpyrazin-2-yl)butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-methyl-4-(3-methyl-2-pyridinyl)butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[(4-methyl-3-pyridinyl)oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(2-methylquinolin-4-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[[3-(trifluoromethyl)-4-pyridinyl]oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159317384
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(3,5-dimethyl-2,6-naphthyridin-1-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[3-(trifluoromethyl)isoquinolin-1-yl]butan-1-one;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159674882
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;(1R,5S)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclopropyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159830262
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-methoxyimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylquinazolin-4-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[2-(trifluoromethyl)quinazolin-4-yl]butan-1-one;(1S,5R)-N-[2-(5-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(8-methylimidazo[1,5-a]pyridin-3-yl)cyclobutyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159841028
5-[4-(2-azabicyclo[2.1.1]hexan-2-yl)-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl]-3-cyclopropylpyridin-2-amine;4-cyclopropyl-2-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazine;3-(cyclopropylmethoxy)-5-[4-(3,3-difluoropyrrolidin-1-yl)-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl]pyridin-2-amine;5-[4-(cyclopropylmethoxy)-6,6-dimethyl-8,9-dihydropurino[8,9-c][1,4]oxazin-2-yl]pyrimidin-2-amine
CID 160097810
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-methoxyimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;(1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3,6-dimethylisoquinolin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(5-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 160281573
N-butyl-2-methyl-5-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]pyrrolo[3,2-d]pyrimidin-4-amine;N-(2-methoxyethyl)-5-[(3-methoxy-2-pyridinyl)methyl]-2-methylpyrrolo[3,2-d]pyrimidin-4-amine;5-(2-methoxyethyl)-4-N-[(5-methyl-1,2-oxazol-3-yl)methyl]pyrrolo[3,2-d]pyrimidine-2,4-diamine;N-(2-methoxyethyl)-2-methyl-5-[[5-(trifluoromethyl)-2-pyridinyl]methyl]pyrrolo[3,2-d]pyrimidin-4-amine;4-N-(2-methoxyethyl)-5-[3-(2-propylphenyl)propyl]pyrrolo[3,2-d]pyrimidine-2,4-diamine;5-[3-(3-methoxy-4-pyridinyl)propyl]-4-N-[(5-methyl-1,2-oxazol-3-yl)methyl]pyrrolo[3,2-d]pyrimidine-2,4-diamine;2-methyl-N-[(5-methyl-1,2-oxazol-3-yl)methyl]-5-[[5-(trifluoromethyl)-2-pyridinyl]methyl]pyrrolo[3,2-d]pyrimidin-4-amine
CID 160906083
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(1-cyclopropyl-8-fluoroimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(8-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one;(1S,5R)-N-[2-(8-fluoro-1-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161125514
1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2-cyclopropylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-methoxyimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;(1R,5S)-N-[2-(2,7-dimethyl-1,6-naphthyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(5-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161193496
(1S,5R)-N-[2-(3,4-dihydro-2H-chromen-2-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-4-(3-methyl-2-pyridinyl)butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(1-methylpyrazolo[4,3-b]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-4-[3-(trifluoromethyl)-2-pyridinyl]butan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-methyl-1-[[3-(trifluoromethyl)-4-pyridinyl]oxy]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-quinolin-2-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161708802

Frequently Asked Questions

What is the IUPAC name of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one?
The IUPAC name of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one (CID 162095937) is 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one.
What is the SMILES notation for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one?
The canonical SMILES for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one is CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(C3CC3)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(OC(F)(F)F)cccn12.CC(C)(CC(=O)C1[C@H]2CNC[C@@H]12)c1ncnc2c(F)cccc12.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C)c2n1.Cc1nc(C(C)(C)CC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1nc2ccccn2c1C(C)(C)CC(=O)C1[C@H]2CNC[C@@H]12.
What is the InChIKey of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one?
The InChIKey is ZEFZWCADDKCOFW-ASDFBCLJSA-N. The full InChI is InChI=1S/2C20H25N3O.C18H20F3N3O2.C18H20FN3O.2C18H23N3O/c1-20(2,8-17(24)18-14-9-21-10-15(14)18)19-22-11-16-13(12-5-6-12)4-3-7-23(16)19;1-11-6-5-7-13-18(11)22-12(2)23-19(13)20(3,4)8-16(24)17-14-9-21-10-15(14)17;1-17(2,6-13(25)15-10-7-22-8-11(10)15)16-23-9-12-14(26-18(19,20)21)4-3-5-24(12)16;1-18(2,6-14(23)15-11-7-20-8-12(11)15)17-10-4-3-5-13(19)16(10)21-9-22-17;1-11-17(21-7-5-4-6-15(21)20-11)18(2,3)8-14(22)16-12-9-19-10-13(12)16;1-11-20-17(14-6-4-5-7-21(11)14)18(2,3)8-15(22)16-12-9-19-10-13(12)16/h3-4,7,11-12,14-15,18,21H,5-6,8-10H2,1-2H3;5-7,14-15,17,21H,8-10H2,1-4H3;3-5,9-11,15,22H,6-8H2,1-2H3;3-5,9,11-12,15,20H,6-8H2,1-2H3;2*4-7,12-13,16,19H,8-10H2,1-3H3/t14-,15+,18?;14-,15+,17?;10-,11+,15?;11-,12+,15?;2*12-,13+,16?.
What are the key properties of 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one?
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one has a molecular weight of 1922.43 g/mol, XLogP of 15.96, 26 rotatable bonds, 6 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-cyclopropylimidazo[1,5-a]pyridin-3-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(2,8-dimethylquinazolin-4-yl)-3-methylbutan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-(8-fluoroquinazolin-4-yl)-3-methylbutan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(2-methylimidazo[1,2-a]pyridin-3-yl)butan-1-one;1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(3-methylimidazo[1,5-a]pyridin-1-yl)butan-1-one;1-[(1S,5R)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-[8-(trifluoromethoxy)imidazo[1,5-a]pyridin-3-yl]butan-1-one is sourced from PubChem (CID 162095937), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).