6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

C96H74ClF15N28O — CID 159722055

About 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine

6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (PubChem CID 159722055) has the molecular formula C96H74ClF15N28O and a molecular weight of 1956.27 g/mol. Its IUPAC name is 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.

Molecular Properties

• Compound Name: 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
• PubChem CID: 159722055
• Molecular Formula: C96H74ClF15N28O
• Molecular Weight: 1956.27 g/mol
• Exact Mass: 1954.60
• IUPAC Name: 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine
• SMILES: COc1c(F)cc(Nc2cc(C#N)cc(-c3c(C4CC4)nc4ccc(F)cn34)n2)cc1F.Cc1cc(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)ccn1.Cc1cnc(C)n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(CCn2ncnn2)c(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.FC(F)(F)c1ccc(Nc2cncc(-c3ccnc(-c4ccnc(Cl)c4)c3)n2)cc1
• InChI: InChI=1S/C23H16F3N5O.C21H13ClF3N5.C19H18F3N9.C17H13F3N4.C16H14F3N5/c1-32-23-16(25)8-15(9-17(23)26)28-19-7-12(10-27)6-18(29-19)22-21(13-2-3-13)30-20-5-4-14(24)11-31(20)22;22-19-10-14(6-8-28-19)17-9-13(5-7-27-17)18-11-26-12-20(30-18)29-16-3-1-15(2-4-16)21(23,24)25;1-12-18(13(2)30(28-12)7-8-31-25-11-24-29-31)16-9-23-10-17(27-16)26-15-5-3-14(4-6-15)19(20,21)22;1-11-8-12(6-7-22-11)15-9-21-10-16(24-15)23-14-4-2-13(3-5-14)17(18,19)20;1-10-7-21-11(2)24(10)15-9-20-8-14(23-15)22-13-5-3-12(4-6-13)16(17,18)19/h4-9,11,13H,2-3H2,1H3,(H,28,29);1-12H,(H,29,30);3-6,9-11H,7-8H2,1-2H3,(H,26,27);2-10H,1H3,(H,23,24);3-9H,1-2H3,(H,22,23)
• InChIKey: NADVEHDPCWIUGV-UHFFFAOYSA-N
• XLogP: 23.39
• TPSA: 344.39 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 29
• Rotatable Bonds: 21
• Heavy Atoms: 141
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1956.27
LogP ≤ 5	23.39
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The IUPAC name of 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine (CID 159722055) is 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine.

What is the SMILES notation for 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The canonical SMILES for 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is COc1c(F)cc(Nc2cc(C#N)cc(-c3c(C4CC4)nc4ccc(F)cn34)n2)cc1F.Cc1cc(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)ccn1.Cc1cnc(C)n1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(CCn2ncnn2)c(C)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.FC(F)(F)c1ccc(Nc2cncc(-c3ccnc(-c4ccnc(Cl)c4)c3)n2)cc1.

What is the InChIKey of 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

The InChIKey is NADVEHDPCWIUGV-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H16F3N5O.C21H13ClF3N5.C19H18F3N9.C17H13F3N4.C16H14F3N5/c1-32-23-16(25)8-15(9-17(23)26)28-19-7-12(10-27)6-18(29-19)22-21(13-2-3-13)30-20-5-4-14(24)11-31(20)22;22-19-10-14(6-8-28-19)17-9-13(5-7-27-17)18-11-26-12-20(30-18)29-16-3-1-15(2-4-16)21(23,24)25;1-12-18(13(2)30(28-12)7-8-31-25-11-24-29-31)16-9-23-10-17(27-16)26-15-5-3-14(4-6-15)19(20,21)22;1-11-8-12(6-7-22-11)15-9-21-10-16(24-15)23-14-4-2-13(3-5-14)17(18,19)20;1-10-7-21-11(2)24(10)15-9-20-8-14(23-15)22-13-5-3-12(4-6-13)16(17,18)19/h4-9,11,13H,2-3H2,1H3,(H,28,29);1-12H,(H,29,30);3-6,9-11H,7-8H2,1-2H3,(H,26,27);2-10H,1H3,(H,23,24);3-9H,1-2H3,(H,22,23).

What are the key properties of 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine?

6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine has a molecular weight of 1956.27 g/mol, XLogP of 23.39, 21 rotatable bonds, 5 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-(2-chloro-4-pyridinyl)-4-pyridinyl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-(3,5-difluoro-4-methoxyanilino)pyridine-4-carbonitrile;6-(2,5-dimethylimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-[3,5-dimethyl-1-[2-(tetrazol-2-yl)ethyl]pyrazol-4-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methyl-4-pyridinyl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine is sourced from PubChem (CID 159722055), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).