N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide

C110H92F21N13O12 — CID 159750293

About N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide

N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide (PubChem CID 159750293) has the molecular formula C110H92F21N13O12 and a molecular weight of 2186.98 g/mol. Its IUPAC name is N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide.

Molecular Properties

• Compound Name: N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide
• PubChem CID: 159750293
• Molecular Formula: C110H92F21N13O12
• Molecular Weight: 2186.98 g/mol
• Exact Mass: 2185.67
• IUPAC Name: N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide
• SMILES: CC(C)c1cccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)c1.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2ccc(F)cc2F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2C(F)(F)F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2F)C1=O.Cc1cc(F)ccc1NC(=O)C1C(=O)NCC1c1cc(F)cc(F)c1.Cc1ccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)cn1
• InChI: InChI=1S/C20H20F2N2O2.C19H14F6N2O2.2C18H14F4N2O2.C18H15F3N2O2.C17H15F2N3O2/c1-11(2)12-5-3-6-13(9-12)14-10-23-19(25)17(14)20(26)24-16-8-4-7-15(21)18(16)22;1-27-8-12(9-5-10(20)7-11(21)6-9)15(18(27)29)17(28)26-14-4-2-3-13(22)16(14)19(23,24)25;1-24-8-13(9-4-11(20)6-12(21)5-9)16(18(24)26)17(25)23-15-3-2-10(19)7-14(15)22;1-24-8-12(9-5-10(19)7-11(20)6-9)15(18(24)26)17(25)23-14-4-2-3-13(21)16(14)22;1-9-4-11(19)2-3-15(9)23-18(25)16-14(8-22-17(16)24)10-5-12(20)7-13(21)6-10;1-9-5-6-10(7-20-9)11-8-21-16(23)14(11)17(24)22-13-4-2-3-12(18)15(13)19/h3-9,11,14,17H,10H2,1-2H3,(H,23,25)(H,24,26);2-7,12,15H,8H2,1H3,(H,26,28);2-7,13,16H,8H2,1H3,(H,23,25);2-7,12,15H,8H2,1H3,(H,23,25);2-7,14,16H,8H2,1H3,(H,22,24)(H,23,25);2-7,11,14H,8H2,1H3,(H,21,23)(H,22,24)
• InChIKey: NDOIVGXVPJHPMR-UHFFFAOYSA-N
• XLogP: 18.61
• TPSA: 335.72 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 13
• Rotatable Bonds: 19
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2186.98
LogP ≤ 5	18.61
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	13

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide?

The IUPAC name of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide (CID 159750293) is N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide.

What is the SMILES notation for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide?

The canonical SMILES for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide is CC(C)c1cccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)c1.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2ccc(F)cc2F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2C(F)(F)F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2F)C1=O.Cc1cc(F)ccc1NC(=O)C1C(=O)NCC1c1cc(F)cc(F)c1.Cc1ccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)cn1.

What is the InChIKey of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide?

The InChIKey is NDOIVGXVPJHPMR-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H20F2N2O2.C19H14F6N2O2.2C18H14F4N2O2.C18H15F3N2O2.C17H15F2N3O2/c1-11(2)12-5-3-6-13(9-12)14-10-23-19(25)17(14)20(26)24-16-8-4-7-15(21)18(16)22;1-27-8-12(9-5-10(20)7-11(21)6-9)15(18(27)29)17(28)26-14-4-2-3-13(22)16(14)19(23,24)25;1-24-8-13(9-4-11(20)6-12(21)5-9)16(18(24)26)17(25)23-15-3-2-10(19)7-14(15)22;1-24-8-12(9-5-10(19)7-11(20)6-9)15(18(24)26)17(25)23-14-4-2-3-13(21)16(14)22;1-9-4-11(19)2-3-15(9)23-18(25)16-14(8-22-17(16)24)10-5-12(20)7-13(21)6-10;1-9-5-6-10(7-20-9)11-8-21-16(23)14(11)17(24)22-13-4-2-3-12(18)15(13)19/h3-9,11,14,17H,10H2,1-2H3,(H,23,25)(H,24,26);2-7,12,15H,8H2,1H3,(H,26,28);2-7,13,16H,8H2,1H3,(H,23,25);2-7,12,15H,8H2,1H3,(H,23,25);2-7,14,16H,8H2,1H3,(H,22,24)(H,23,25);2-7,11,14H,8H2,1H3,(H,21,23)(H,22,24).

What are the key properties of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide?

N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide has a molecular weight of 2186.98 g/mol, XLogP of 18.61, 19 rotatable bonds, 9 hydrogen bond donors, and 13 hydrogen bond acceptors.

Where does this data come from?

All data for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(4-fluoro-2-methylphenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-[3-fluoro-2-(trifluoromethyl)phenyl]-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-4-(6-methyl-3-pyridinyl)-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide is sourced from PubChem (CID 159750293), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).