N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide

C109H89F22N13O12 — CID 164984116

About N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide

N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide (PubChem CID 164984116) has the molecular formula C109H89F22N13O12 and a molecular weight of 2190.95 g/mol. Its IUPAC name is N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide.

Molecular Properties

• Compound Name: N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide
• PubChem CID: 164984116
• Molecular Formula: C109H89F22N13O12
• Molecular Weight: 2190.95 g/mol
• Exact Mass: 2189.64
• IUPAC Name: N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide
• SMILES: CC(C)c1cccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)c1.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2ccc(F)cc2F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2F)C1=O.Cc1c(F)cccc1NC(=O)C1C(=O)N(C)CC1c1cc(F)cc(F)c1.O=C1NCC(c2cc(F)cc(F)c2)C1C(=O)Nc1ccc(F)cc1F.O=C1NCC(c2ccc(C(F)(F)F)nc2)C1C(=O)Nc1cccc(F)c1F
• InChI: InChI=1S/C20H20F2N2O2.C19H17F3N2O2.2C18H14F4N2O2.C17H12F5N3O2.C17H12F4N2O2/c1-11(2)12-5-3-6-13(9-12)14-10-23-19(25)17(14)20(26)24-16-8-4-7-15(21)18(16)22;1-10-15(22)4-3-5-16(10)23-18(25)17-14(9-24(2)19(17)26)11-6-12(20)8-13(21)7-11;1-24-8-13(9-4-11(20)6-12(21)5-9)16(18(24)26)17(25)23-15-3-2-10(19)7-14(15)22;1-24-8-12(9-5-10(19)7-11(20)6-9)15(18(24)26)17(25)23-14-4-2-3-13(21)16(14)22;18-10-2-1-3-11(14(10)19)25-16(27)13-9(7-24-15(13)26)8-4-5-12(23-6-8)17(20,21)22;18-9-1-2-14(13(21)6-9)23-17(25)15-12(7-22-16(15)24)8-3-10(19)5-11(20)4-8/h3-9,11,14,17H,10H2,1-2H3,(H,23,25)(H,24,26);3-8,14,17H,9H2,1-2H3,(H,23,25);2-7,13,16H,8H2,1H3,(H,23,25);2-7,12,15H,8H2,1H3,(H,23,25);1-6,9,13H,7H2,(H,24,26)(H,25,27);1-6,12,15H,7H2,(H,22,24)(H,23,25)
• InChIKey: FXGLPIWREWZKQQ-UHFFFAOYSA-N
• XLogP: 18.44
• TPSA: 335.72 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 13
• Rotatable Bonds: 19
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2190.95
LogP ≤ 5	18.44
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	13

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide?

The IUPAC name of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide (CID 164984116) is N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide.

What is the SMILES notation for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide?

The canonical SMILES for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide is CC(C)c1cccc(C2CNC(=O)C2C(=O)Nc2cccc(F)c2F)c1.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2ccc(F)cc2F)C1=O.CN1CC(c2cc(F)cc(F)c2)C(C(=O)Nc2cccc(F)c2F)C1=O.Cc1c(F)cccc1NC(=O)C1C(=O)N(C)CC1c1cc(F)cc(F)c1.O=C1NCC(c2cc(F)cc(F)c2)C1C(=O)Nc1ccc(F)cc1F.O=C1NCC(c2ccc(C(F)(F)F)nc2)C1C(=O)Nc1cccc(F)c1F.

What is the InChIKey of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide?

The InChIKey is FXGLPIWREWZKQQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H20F2N2O2.C19H17F3N2O2.2C18H14F4N2O2.C17H12F5N3O2.C17H12F4N2O2/c1-11(2)12-5-3-6-13(9-12)14-10-23-19(25)17(14)20(26)24-16-8-4-7-15(21)18(16)22;1-10-15(22)4-3-5-16(10)23-18(25)17-14(9-24(2)19(17)26)11-6-12(20)8-13(21)7-11;1-24-8-13(9-4-11(20)6-12(21)5-9)16(18(24)26)17(25)23-15-3-2-10(19)7-14(15)22;1-24-8-12(9-5-10(19)7-11(20)6-9)15(18(24)26)17(25)23-14-4-2-3-13(21)16(14)22;18-10-2-1-3-11(14(10)19)25-16(27)13-9(7-24-15(13)26)8-4-5-12(23-6-8)17(20,21)22;18-9-1-2-14(13(21)6-9)23-17(25)15-12(7-22-16(15)24)8-3-10(19)5-11(20)4-8/h3-9,11,14,17H,10H2,1-2H3,(H,23,25)(H,24,26);3-8,14,17H,9H2,1-2H3,(H,23,25);2-7,13,16H,8H2,1H3,(H,23,25);2-7,12,15H,8H2,1H3,(H,23,25);1-6,9,13H,7H2,(H,24,26)(H,25,27);1-6,12,15H,7H2,(H,22,24)(H,23,25).

What are the key properties of N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide?

N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide has a molecular weight of 2190.95 g/mol, XLogP of 18.44, 19 rotatable bonds, 9 hydrogen bond donors, and 13 hydrogen bond acceptors.

Where does this data come from?

All data for N-(2,3-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,4-difluorophenyl)-4-(3,5-difluorophenyl)-2-oxopyrrolidine-3-carboxamide;4-(3,5-difluorophenyl)-N-(3-fluoro-2-methylphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-(3-propan-2-ylphenyl)pyrrolidine-3-carboxamide;N-(2,3-difluorophenyl)-2-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]pyrrolidine-3-carboxamide is sourced from PubChem (CID 164984116), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).