N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide

C84H84Cl3F10N9O12 — CID 159753805

IUPACN-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide
SMILESCc1ccc(C(=O)N(C)c2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2F)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(F)cn2)cc1C(F)(F)C(=O)N1CCC(O)CC1
InChIInChI=1S/C22H23ClF2N2O3.C21H20ClF3N2O3.C21H21ClF2N2O3.C20H20F3N3O3/c1-14-3-4-15(20(29)26(2)17-7-5-16(23)6-8-17)13-19(14)22(24,25)21(30)27-11-9-18(28)10-12-27;1-12-2-3-13(19(29)26-18-5-4-14(22)11-17(18)23)10-16(12)21(24,25)20(30)27-8-6-15(28)7-9-27;1-13-2-3-14(19(28)25-16-6-4-15(22)5-7-16)12-18(13)21(23,24)20(29)26-10-8-17(27)9-11-26;1-12-2-3-13(18(28)25-17-5-4-14(21)11-24-17)10-16(12)20(22,23)19(29)26-8-6-15(27)7-9-26/h3-8,13,18,28H,9-12H2,1-2H3;2-5,10-11,15,28H,6-9H2,1H3,(H,26,29);2-7,12,17,27H,8-11H2,1H3,(H,25,28);2-5,10-11,15,27H,6-9H2,1H3,(H,24,25,28)
InChIKeyNDZLBUUOELGHQF-UHFFFAOYSA-N
MW1707.99 g/mol
LogP14.95
Rot. Bonds16

About N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide

N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide (PubChem CID 159753805) has the molecular formula C84H84Cl3F10N9O12 and a molecular weight of 1707.99 g/mol. Its IUPAC name is N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide.

Molecular Properties

Compound NameN-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide
PubChem CID159753805
Molecular FormulaC84H84Cl3F10N9O12
Molecular Weight1707.99 g/mol
Exact Mass1705.51
IUPAC NameN-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide
SMILESCc1ccc(C(=O)N(C)c2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2F)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(F)cn2)cc1C(F)(F)C(=O)N1CCC(O)CC1
InChIInChI=1S/C22H23ClF2N2O3.C21H20ClF3N2O3.C21H21ClF2N2O3.C20H20F3N3O3/c1-14-3-4-15(20(29)26(2)17-7-5-16(23)6-8-17)13-19(14)22(24,25)21(30)27-11-9-18(28)10-12-27;1-12-2-3-13(19(29)26-18-5-4-14(22)11-17(18)23)10-16(12)21(24,25)20(30)27-8-6-15(28)7-9-27;1-13-2-3-14(19(28)25-16-6-4-15(22)5-7-16)12-18(13)21(23,24)20(29)26-10-8-17(27)9-11-26;1-12-2-3-13(18(28)25-17-5-4-14(21)11-24-17)10-16(12)20(22,23)19(29)26-8-6-15(27)7-9-26/h3-8,13,18,28H,9-12H2,1-2H3;2-5,10-11,15,28H,6-9H2,1H3,(H,26,29);2-7,12,17,27H,8-11H2,1H3,(H,25,28);2-5,10-11,15,27H,6-9H2,1H3,(H,24,25,28)
InChIKeyNDZLBUUOELGHQF-UHFFFAOYSA-N
XLogP14.95
TPSA282.66 Ų
H-Bond Donors7
H-Bond Acceptors13
Rotatable Bonds16
Heavy Atoms118
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001707.99
LogP ≤ 514.95
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1013

Analyze N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide with MolForge

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Related Compounds

1-[3-chloro-5-(1-hydroxypropan-2-yl)-2-pyridinyl]-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;1-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)piperazine-1-carboxamide;2-methyl-N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide
CID 157225509
(2R)-4-[3-chloro-5-(1-hydroxypropan-2-yl)-2-pyridinyl]-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;1-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)piperazine-1-carboxamide;(2R)-2-methyl-N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide
CID 157625358
3-(4-acetamidopiperidin-1-yl)-N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(4-hydroxypiperidin-1-yl)-5-(trifluoromethyl)benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-(dimethylamino)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]benzamide
CID 159986042
N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide
CID 161420092
CID 161445164
CID 161445164
4-(3-chloro-2-pyridinyl)-N-[3-[2-(dimethylamino)ethyl]-4-methylphenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[3-[2-(dimethylamino)ethyl]-4-methylphenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-N-[3-[(dimethylamino)methyl]-4-methylphenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[3-[(dimethylamino)methyl]-4-methylphenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;1-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;N-(5-methyl-2-pyridinyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide
CID 161863356
N-(2-chloro-4-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide
CID 163661066
4-tert-butyl-N-[2-[4-[2-[[2-(dimethylamino)-2-oxoethyl]-methylamino]ethyl]piperidin-1-yl]-3-pyridinyl]benzamide;3-chloro-N-[5-chloro-2-[4-(piperidin-1-ylmethyl)piperidin-1-yl]-3-pyridinyl]benzamide;3-chloro-N-[5-chloro-2-[4-(3-piperidin-1-ylpropyl)piperidin-1-yl]-3-pyridinyl]benzamide;2-[2-[4-(piperidin-1-ylmethyl)piperidin-1-yl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 173067517
2-[(4-carbamimidoyl-2-fluorobenzoyl)amino]-5-chloro-N-(5-chloro-2-pyridinyl)-3-methylbenzamide;bis(5-chloro-N-(5-chloro-2-pyridinyl)-2-[(4-ethanimidoyl-2-fluorobenzoyl)amino]-3-methylbenzamide);5-chloro-N-(5-chloro-2-pyridinyl)-2-[[2-fluoro-4-(piperidine-1-carboximidoyl)benzoyl]amino]-3-methylbenzamide;5-chloro-N-(5-chloro-2-pyridinyl)-2-[[2-fluoro-4-(pyrrolidine-1-carboximidoyl)benzoyl]amino]-3-methylbenzamide
CID 91098083
2-[2-[4-(azetidine-1-carboximidoyl)phenyl]ethyl]-N-(5-chloro-2-pyridinyl)-5-fluorobenzamide;N-(5-chloro-2-pyridinyl)-2-[2-(4-ethanimidoylphenyl)ethyl]-5-fluorobenzamide;N-(5-chloro-2-pyridinyl)-5-fluoro-2-[2-[4-(1-methyl-4,5-dihydroimidazol-2-yl)phenyl]ethyl]benzamide;N-(5-chloro-2-pyridinyl)-5-fluoro-2-[2-[4-(piperidine-1-carboximidoyl)phenyl]ethyl]benzamide
CID 157083823
4-chloro-N-[1-[5-[(2,6-dimethylmorpholin-4-yl)methyl]-2-pyridinyl]piperidin-4-yl]-3-pyridin-3-ylbenzamide;4-chloro-N-[1-[5-[(3,5-dimethylpiperazin-1-yl)methyl]-2-pyridinyl]piperidin-4-yl]-3-pyridin-3-ylbenzamide;N-[1-[5-[(2,6-dimethylmorpholin-4-yl)methyl]-2-pyridinyl]piperidin-4-yl]-4-fluoro-3-pyridin-3-ylbenzamide;N-[1-[5-[(2,6-dimethylmorpholin-4-yl)methyl]-2-pyridinyl]piperidin-4-yl]-4-methyl-3-pyridin-3-ylbenzamide;N-[1-[5-[(3,5-dimethylpiperazin-1-yl)methyl]-2-pyridinyl]piperidin-4-yl]-4-fluoro-3-pyridin-3-ylbenzamide;N-[1-[5-[(3,5-dimethylpiperazin-1-yl)methyl]-2-pyridinyl]piperidin-4-yl]-4-methyl-3-pyridin-3-ylbenzamide
CID 157166701
2-[2-(4-carbamimidoylphenyl)-2-oxoethyl]-N-(5-chloro-2-pyridinyl)-4,5-difluorobenzamide;N-(5-chloro-2-pyridinyl)-4,5-difluoro-2-[2-[4-(N'-methylcarbamimidoyl)phenyl]-2-oxoethyl]benzamide;N-(5-chloro-2-pyridinyl)-2-[2-[4-(N,N-dimethylcarbamimidoyl)phenyl]-2-oxoethyl]-4,5-difluorobenzamide
CID 157230605

Frequently Asked Questions

What is the IUPAC name of N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide?
The IUPAC name of N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide (CID 159753805) is N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide.
What is the SMILES notation for N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide?
The canonical SMILES for N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide is Cc1ccc(C(=O)N(C)c2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(Cl)cc2F)cc1C(F)(F)C(=O)N1CCC(O)CC1.Cc1ccc(C(=O)Nc2ccc(F)cn2)cc1C(F)(F)C(=O)N1CCC(O)CC1.
What is the InChIKey of N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide?
The InChIKey is NDZLBUUOELGHQF-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H23ClF2N2O3.C21H20ClF3N2O3.C21H21ClF2N2O3.C20H20F3N3O3/c1-14-3-4-15(20(29)26(2)17-7-5-16(23)6-8-17)13-19(14)22(24,25)21(30)27-11-9-18(28)10-12-27;1-12-2-3-13(19(29)26-18-5-4-14(22)11-17(18)23)10-16(12)21(24,25)20(30)27-8-6-15(28)7-9-27;1-13-2-3-14(19(28)25-16-6-4-15(22)5-7-16)12-18(13)21(23,24)20(29)26-10-8-17(27)9-11-26;1-12-2-3-13(18(28)25-17-5-4-14(21)11-24-17)10-16(12)20(22,23)19(29)26-8-6-15(27)7-9-26/h3-8,13,18,28H,9-12H2,1-2H3;2-5,10-11,15,28H,6-9H2,1H3,(H,26,29);2-7,12,17,27H,8-11H2,1H3,(H,25,28);2-5,10-11,15,27H,6-9H2,1H3,(H,24,25,28).
What are the key properties of N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide?
N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide has a molecular weight of 1707.99 g/mol, XLogP of 14.95, 16 rotatable bonds, 7 hydrogen bond donors, and 13 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide is sourced from PubChem (CID 159753805), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).