N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide

C228H190Cl2F15N29O21 — CID 161420092

IUPACN-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide
SMILESCOCCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)NCc3ccccc3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cc3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)cc1.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)nc1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(C(F)(F)F)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(Cl)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C\Cc3ccccc3)cc2n(C)c1=O
InChIInChI=1S/C33H23F6N3O2.C33H26F3N3O2.C32H23ClF3N3O2.C28H26F3N3O3.2C26H24N4O3.C25H21ClN4O3.C25H23N5O3/c1-19-6-12-26(41-30(43)21-4-3-5-24(14-21)33(37,38)39)16-27(19)28-15-22-18-40-25(17-29(22)42(2)31(28)44)13-9-20-7-10-23(11-8-20)32(34,35)36;1-21-14-15-27(38-31(40)23-11-7-12-25(16-23)33(34,35)36)18-28(21)29-17-24-20-37-26(19-30(24)39(2)32(29)41)13-6-10-22-8-4-3-5-9-22;1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-9-10-22(33-26(35)18-6-4-7-20(12-18)28(29,30)31)14-23(17)24-13-19-16-32-21(8-5-11-37-3)15-25(19)34(2)27(24)36;1-15-5-9-20(10-6-15)28-26(33)29-24(31)18-8-7-16(2)21(12-18)22-13-19-14-27-17(3)11-23(19)30(4)25(22)32;1-16-9-10-19(24(31)29-26(33)28-14-18-7-5-4-6-8-18)12-21(16)22-13-20-15-27-17(2)11-23(20)30(3)25(22)32;1-14-4-5-16(23(31)29-25(33)28-19-8-6-18(26)7-9-19)11-20(14)21-12-17-13-27-15(2)10-22(17)30(3)24(21)32;1-14-5-8-22(27-12-14)28-25(33)29-23(31)17-7-6-15(2)19(10-17)20-11-18-13-26-16(3)9-21(18)30(4)24(20)32/h3-18H,1-2H3,(H,41,43);3-9,11-20H,10H2,1-2H3,(H,38,40);3-18H,1-2H3,(H,38,40);4,6-7,9-10,12-16H,5,8,11H2,1-3H3,(H,33,35);5-14H,1-4H3,(H2,28,29,31,33);4-13,15H,14H2,1-3H3,(H2,28,29,31,33);4-13H,1-3H3,(H2,28,29,31,33);5-13H,1-4H3,(H2,27,28,29,31,33)/b13-9+;13-6-;13-9+;;;;;
InChIKeyVWPOEVSOEKMEBX-IQAPDVTOSA-N
MW4028.09 g/mol
LogP46.63
Rot. Bonds36

About N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide

N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide (PubChem CID 161420092) has the molecular formula C228H190Cl2F15N29O21 and a molecular weight of 4028.09 g/mol. Its IUPAC name is N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound NameN-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide
PubChem CID161420092
Molecular FormulaC228H190Cl2F15N29O21
Molecular Weight4028.09 g/mol
Exact Mass4024.38
IUPAC NameN-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide
SMILESCOCCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)NCc3ccccc3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cc3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)cc1.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)nc1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(C(F)(F)F)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(Cl)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C\Cc3ccccc3)cc2n(C)c1=O
InChIInChI=1S/C33H23F6N3O2.C33H26F3N3O2.C32H23ClF3N3O2.C28H26F3N3O3.2C26H24N4O3.C25H21ClN4O3.C25H23N5O3/c1-19-6-12-26(41-30(43)21-4-3-5-24(14-21)33(37,38)39)16-27(19)28-15-22-18-40-25(17-29(22)42(2)31(28)44)13-9-20-7-10-23(11-8-20)32(34,35)36;1-21-14-15-27(38-31(40)23-11-7-12-25(16-23)33(34,35)36)18-28(21)29-17-24-20-37-26(19-30(24)39(2)32(29)41)13-6-10-22-8-4-3-5-9-22;1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-9-10-22(33-26(35)18-6-4-7-20(12-18)28(29,30)31)14-23(17)24-13-19-16-32-21(8-5-11-37-3)15-25(19)34(2)27(24)36;1-15-5-9-20(10-6-15)28-26(33)29-24(31)18-8-7-16(2)21(12-18)22-13-19-14-27-17(3)11-23(19)30(4)25(22)32;1-16-9-10-19(24(31)29-26(33)28-14-18-7-5-4-6-8-18)12-21(16)22-13-20-15-27-17(2)11-23(20)30(3)25(22)32;1-14-4-5-16(23(31)29-25(33)28-19-8-6-18(26)7-9-19)11-20(14)21-12-17-13-27-15(2)10-22(17)30(3)24(21)32;1-14-5-8-22(27-12-14)28-25(33)29-23(31)17-7-6-15(2)19(10-17)20-11-18-13-26-16(3)9-21(18)30(4)24(20)32/h3-18H,1-2H3,(H,41,43);3-9,11-20H,10H2,1-2H3,(H,38,40);3-18H,1-2H3,(H,38,40);4,6-7,9-10,12-16H,5,8,11H2,1-3H3,(H,33,35);5-14H,1-4H3,(H2,28,29,31,33);4-13,15H,14H2,1-3H3,(H2,28,29,31,33);4-13H,1-3H3,(H2,28,29,31,33);5-13H,1-4H3,(H2,27,28,29,31,33)/b13-9+;13-6-;13-9+;;;;;
InChIKeyVWPOEVSOEKMEBX-IQAPDVTOSA-N
XLogP46.63
TPSA650.44 Ų
H-Bond Donors12
H-Bond Acceptors38
Rotatable Bonds36
Heavy Atoms295
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004028.09
LogP ≤ 546.63
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1038

Analyze N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide with MolForge

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Related Compounds

1-[3-chloro-5-(1-hydroxypropan-2-yl)-2-pyridinyl]-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;1-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)piperazine-1-carboxamide;2-methyl-N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide
CID 157225509
4-[5-(1-acetamidoethyl)-3-chloro-2-pyridinyl]-N-[3-methyl-4-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine-1-carboxamide;4-[5-(1-acetamidoethyl)-3-chloro-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridine-1-carboxamide;4-[5-(acetamidomethyl)-3-chloro-2-pyridinyl]-N-[4-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine-1-carboxamide;4-[5-(acetamidomethyl)-3-chloro-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridine-1-carboxamide;4-[5-(2-amino-2-oxoethyl)-3-chloro-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridine-1-carboxamide;4-[3-chloro-5-[2-(ethylamino)-2-oxoethyl]-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-3,6-dihydro-2H-pyridine-1-carboxamide
CID 157567710
1-(2,4-Dichlorophenyl)-3-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]urea;1-[3-[7-(dimethylamino)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-phenylurea;1-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]urea;1-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 157618797
(2R)-4-[3-chloro-5-(1-hydroxypropan-2-yl)-2-pyridinyl]-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-2-methyl-N-(4-methylphenyl)piperazine-1-carboxamide;1-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)-3,6-dihydro-2H-pyridine-4-carboxamide;4-(3-chloro-2-pyridinyl)-N-(4-methylphenyl)piperazine-1-carboxamide;(2R)-2-methyl-N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]piperazine-1-carboxamide
CID 157625358
7-chloro-1-propan-2-ylnaphthalene;8-propan-2-ylisoquinolin-1-amine;1-propan-2-ylnaphthalene;1-propan-2-yl-2,7-naphthyridine;4-propan-2-yl-1,6-naphthyridine;5-propan-2-ylquinoline;4-propan-2-ylquinoline-6-carboxamide;5-propan-2-yl-1H-quinolin-4-one;4-propan-2-yl-7-(trifluoromethyl)-1,6-naphthyridine;4-propan-2-yl-7-(trifluoromethyl)quinoline
CID 157915643
1-[(4-Chlorophenyl)methyl]-3-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]urea;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]urea;1-[(3,4-dichlorophenyl)methyl]-3-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]urea;1-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]urea;1-[3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-[(4-methylphenyl)methyl]urea
CID 158937287
3-[2-(3-amino-6-chloroisoquinolin-4-yl)ethynyl]-N-[2-(diethylamino)ethyl]-4-methylbenzamide;3-[2-(3-amino-8-chloroisoquinolin-4-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;3-[2-(3-amino-6-chloroisoquinolin-4-yl)ethynyl]-4-methyl-N-(2-piperidin-1-ylethyl)benzamide;3-[2-(3-amino-6-methylisoquinolin-4-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
CID 159002256
N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(4-morpholin-4-yl-2-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;1-[4-methyl-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone
CID 159588365
N-(4-chloro-2-fluorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N,4-dimethylbenzamide;N-(4-chlorophenyl)-3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-4-methylbenzamide;3-[1,1-difluoro-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-N-(5-fluoro-2-pyridinyl)-4-methylbenzamide
CID 159753805
3-(4-acetamidopiperidin-1-yl)-N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(4-hydroxypiperidin-1-yl)-5-(trifluoromethyl)benzamide;N-[3-(7-chloro-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-(dimethylamino)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]benzamide
CID 159986042
tert-butyl N-[1-[4-(5-amino-2-methylphenyl)-6-chloro-2-pyridinyl]-4-methylpiperidin-4-yl]carbamate;tert-butyl N-[1-[6-chloro-4-[5-[[2-(1,1-difluoroethyl)pyridine-4-carbonyl]amino]-2-methylphenyl]-2-pyridinyl]-4-methylpiperidin-4-yl]carbamate;tert-butyl N-[1-[6-(3,6-dihydro-2H-pyran-4-yl)-4-[2-methyl-5-[[2-(trifluoromethyl)pyridine-4-carbonyl]amino]phenyl]-2-pyridinyl]-4-methylpiperidin-4-yl]carbamate;tert-butyl N-[4-methyl-1-[4-[2-methyl-5-[[2-(trifluoromethyl)piperidine-4-carbonyl]amino]phenyl]-6-(oxan-4-yl)-2-pyridinyl]piperidin-4-yl]carbamate;3-(2,6-dichloro-4-pyridinyl)-4-methylaniline
CID 160100520
3-[2-(3-amino-6-chloroisoquinolin-4-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]benzamide;6-[2-(3-amino-6-chloroisoquinolin-4-yl)ethynyl]-5-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]pyridine-2-carboxamide;3-[2-(5-amino-1,6-naphthyridin-8-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
CID 160351174

Frequently Asked Questions

What is the IUPAC name of N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide?
The IUPAC name of N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide (CID 161420092) is N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide is COCCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)NCc3ccccc3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cc3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)cc1.Cc1ccc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)nc1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(C(F)(F)F)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/c3ccc(Cl)cc3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C\Cc3ccccc3)cc2n(C)c1=O.
What is the InChIKey of N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide?
The InChIKey is VWPOEVSOEKMEBX-IQAPDVTOSA-N. The full InChI is InChI=1S/C33H23F6N3O2.C33H26F3N3O2.C32H23ClF3N3O2.C28H26F3N3O3.2C26H24N4O3.C25H21ClN4O3.C25H23N5O3/c1-19-6-12-26(41-30(43)21-4-3-5-24(14-21)33(37,38)39)16-27(19)28-15-22-18-40-25(17-29(22)42(2)31(28)44)13-9-20-7-10-23(11-8-20)32(34,35)36;1-21-14-15-27(38-31(40)23-11-7-12-25(16-23)33(34,35)36)18-28(21)29-17-24-20-37-26(19-30(24)39(2)32(29)41)13-6-10-22-8-4-3-5-9-22;1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-9-10-22(33-26(35)18-6-4-7-20(12-18)28(29,30)31)14-23(17)24-13-19-16-32-21(8-5-11-37-3)15-25(19)34(2)27(24)36;1-15-5-9-20(10-6-15)28-26(33)29-24(31)18-8-7-16(2)21(12-18)22-13-19-14-27-17(3)11-23(19)30(4)25(22)32;1-16-9-10-19(24(31)29-26(33)28-14-18-7-5-4-6-8-18)12-21(16)22-13-20-15-27-17(2)11-23(20)30(3)25(22)32;1-14-4-5-16(23(31)29-25(33)28-19-8-6-18(26)7-9-19)11-20(14)21-12-17-13-27-15(2)10-22(17)30(3)24(21)32;1-14-5-8-22(27-12-14)28-25(33)29-23(31)17-7-6-15(2)19(10-17)20-11-18-13-26-16(3)9-21(18)30(4)24(20)32/h3-18H,1-2H3,(H,41,43);3-9,11-20H,10H2,1-2H3,(H,38,40);3-18H,1-2H3,(H,38,40);4,6-7,9-10,12-16H,5,8,11H2,1-3H3,(H,33,35);5-14H,1-4H3,(H2,28,29,31,33);4-13,15H,14H2,1-3H3,(H2,28,29,31,33);4-13H,1-3H3,(H2,28,29,31,33);5-13H,1-4H3,(H2,27,28,29,31,33)/b13-9+;13-6-;13-9+;;;;;.
What are the key properties of N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide?
N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide has a molecular weight of 4028.09 g/mol, XLogP of 46.63, 36 rotatable bonds, 12 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for N-(benzylcarbamoyl)-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[(4-chlorophenyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-(4-chlorophenyl)ethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methylphenyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-2-pyridinyl)carbamoyl]benzamide;N-[3-[7-(3-methoxypropyl)-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(Z)-3-phenylprop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 161420092), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).