(4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

C115H138Cl3F6N27 — CID 159765246

About (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

(4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (PubChem CID 159765246) has the molecular formula C115H138Cl3F6N27 and a molecular weight of 2118.90 g/mol. Its IUPAC name is (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.

Molecular Properties

• Compound Name: (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
• PubChem CID: 159765246
• Molecular Formula: C115H138Cl3F6N27
• Molecular Weight: 2118.90 g/mol
• Exact Mass: 2116.06
• IUPAC Name: (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
• SMILES: CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccc(Cl)c(Cl)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccnc3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccnc(C(F)(F)F)c3)c3nccn13)CC2
• InChI: InChI=1S/C24H28F3N5.C23H27Cl2N5.C23H28ClN5.C23H27F3N6.C22H28N6/c1-16-20(17-6-3-4-7-18(17)24(25,26)27)21-29-12-15-32(21)22(30-16)31-13-10-23(11-14-31)9-5-8-19(23)28-2;1-15-20(16-5-6-17(24)18(25)14-16)21-27-10-13-30(21)22(28-15)29-11-8-23(9-12-29)7-3-4-19(23)26-2;1-16-20(17-5-3-6-18(24)15-17)21-26-11-14-29(21)22(27-16)28-12-9-23(10-13-28)8-4-7-19(23)25-2;1-15-19(16-5-9-28-18(14-16)23(24,25)26)20-29-10-13-32(20)21(30-15)31-11-7-22(8-12-31)6-3-4-17(22)27-2;1-16-19(17-5-4-10-24-15-17)20-25-11-14-28(20)21(26-16)27-12-8-22(9-13-27)7-3-6-18(22)23-2/h3-4,6-7,12,15,19,28H,5,8-11,13-14H2,1-2H3;5-6,10,13-14,19,26H,3-4,7-9,11-12H2,1-2H3;3,5-6,11,14-15,19,25H,4,7-10,12-13H2,1-2H3;5,9-10,13-14,17,27H,3-4,6-8,11-12H2,1-2H3;4-5,10-11,14-15,18,23H,3,6-9,12-13H2,1-2H3/t3*19-;17-;18-/m11111/s1
• InChIKey: NFKKMSQEMHCHRI-WSCIGCJKSA-N
• XLogP: 23.10
• TPSA: 253.08 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 27
• Rotatable Bonds: 15
• Heavy Atoms: 151
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2118.90
LogP ≤ 5	23.10
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The IUPAC name of (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (CID 159765246) is (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.

What is the SMILES notation for (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The canonical SMILES for (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccc(Cl)c(Cl)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccc3C(F)(F)F)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccnc3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccnc(C(F)(F)F)c3)c3nccn13)CC2.

What is the InChIKey of (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The InChIKey is NFKKMSQEMHCHRI-WSCIGCJKSA-N. The full InChI is InChI=1S/C24H28F3N5.C23H27Cl2N5.C23H28ClN5.C23H27F3N6.C22H28N6/c1-16-20(17-6-3-4-7-18(17)24(25,26)27)21-29-12-15-32(21)22(30-16)31-13-10-23(11-14-31)9-5-8-19(23)28-2;1-15-20(16-5-6-17(24)18(25)14-16)21-27-10-13-30(21)22(28-15)29-11-8-23(9-12-29)7-3-4-19(23)26-2;1-16-20(17-5-3-6-18(24)15-17)21-26-11-14-29(21)22(27-16)28-12-9-23(10-13-28)8-4-7-19(23)25-2;1-15-19(16-5-9-28-18(14-16)23(24,25)26)20-29-10-13-32(20)21(30-15)31-11-7-22(8-12-31)6-3-4-17(22)27-2;1-16-19(17-5-4-10-24-15-17)20-25-11-14-28(20)21(26-16)27-12-8-22(9-13-27)7-3-6-18(22)23-2/h3-4,6-7,12,15,19,28H,5,8-11,13-14H2,1-2H3;5-6,10,13-14,19,26H,3-4,7-9,11-12H2,1-2H3;3,5-6,11,14-15,19,25H,4,7-10,12-13H2,1-2H3;5,9-10,13-14,17,27H,3-4,6-8,11-12H2,1-2H3;4-5,10-11,14-15,18,23H,3,6-9,12-13H2,1-2H3/t3*19-;17-;18-/m11111/s1.

What are the key properties of (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

(4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine has a molecular weight of 2118.90 g/mol, XLogP of 23.10, 15 rotatable bonds, 5 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for (4R)-8-[8-(3-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-8-[8-(3,4-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-(7-methyl-8-pyridin-3-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[2-(trifluoromethyl)-4-pyridinyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is sourced from PubChem (CID 159765246), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).