5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide

C201H212ClF14N61O19S3 — CID 159782615

IUPAC5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
SMILESCC1OCCC1c1cc(Cl)cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2cncs2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCCCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCCCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1
InChIInChI=1S/C26H28F4N8O2.C26H32FN9O3.C25H27ClFN7O3.C25H21F4N7O2S.C25H29FN8O2.C25H24FN7O3.C25H28FN7O2S.C24H23FN8O2S/c27-21-16-32-25(34-23(21)38-8-10-40-11-9-38)36-35-24(39)22-5-4-18(15-31-22)33-19-12-17(26(28,29)30)13-20(14-19)37-6-2-1-3-7-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;1-15-20(4-7-37-15)16-10-17(26)12-19(11-16)30-18-2-3-22(28-13-18)24(35)32-33-25-29-14-21(27)23(31-25)34-5-8-36-9-6-34;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;26-21-17-28-25(30-23(21)34-11-13-36-14-12-34)32-31-24(35)22-8-7-19(16-27-22)29-18-5-4-6-20(15-18)33-9-2-1-3-10-33;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;1-15-8-16(21-13-26-14-36-21)10-18(9-15)29-17-2-3-20(27-11-17)23(34)31-32-24-28-12-19(25)22(30-24)33-4-6-35-7-5-33/h4-5,12-16,33H,1-3,6-11H2,(H,35,39)(H,32,34,36);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);2-3,10-15,20,30H,4-9H2,1H3,(H,32,35)(H,29,31,33);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);4-8,15-17,29H,1-3,9-14H2,(H,31,35)(H,28,30,32);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);2-3,8-14,29H,4-7H2,1H3,(H,31,34)(H,28,30,32)
InChIKeyNHNWMMPDHNLGCM-UHFFFAOYSA-N
MW4183.94 g/mol
LogP29.72
Rot. Bonds58

About 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide

5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide (PubChem CID 159782615) has the molecular formula C201H212ClF14N61O19S3 and a molecular weight of 4183.94 g/mol. Its IUPAC name is 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide.

Molecular Properties

Compound Name5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
PubChem CID159782615
Molecular FormulaC201H212ClF14N61O19S3
Molecular Weight4183.94 g/mol
Exact Mass4180.61
IUPAC Name5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
SMILESCC1OCCC1c1cc(Cl)cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2cncs2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCCCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCCCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1
InChIInChI=1S/C26H28F4N8O2.C26H32FN9O3.C25H27ClFN7O3.C25H21F4N7O2S.C25H29FN8O2.C25H24FN7O3.C25H28FN7O2S.C24H23FN8O2S/c27-21-16-32-25(34-23(21)38-8-10-40-11-9-38)36-35-24(39)22-5-4-18(15-31-22)33-19-12-17(26(28,29)30)13-20(14-19)37-6-2-1-3-7-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;1-15-20(4-7-37-15)16-10-17(26)12-19(11-16)30-18-2-3-22(28-13-18)24(35)32-33-25-29-14-21(27)23(31-25)34-5-8-36-9-6-34;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;26-21-17-28-25(30-23(21)34-11-13-36-14-12-34)32-31-24(35)22-8-7-19(16-27-22)29-18-5-4-6-20(15-18)33-9-2-1-3-10-33;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;1-15-8-16(21-13-26-14-36-21)10-18(9-15)29-17-2-3-20(27-11-17)23(34)31-32-24-28-12-19(25)22(30-24)33-4-6-35-7-5-33/h4-5,12-16,33H,1-3,6-11H2,(H,35,39)(H,32,34,36);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);2-3,10-15,20,30H,4-9H2,1H3,(H,32,35)(H,29,31,33);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);4-8,15-17,29H,1-3,9-14H2,(H,31,35)(H,28,30,32);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);2-3,8-14,29H,4-7H2,1H3,(H,31,34)(H,28,30,32)
InChIKeyNHNWMMPDHNLGCM-UHFFFAOYSA-N
XLogP29.72
TPSA902.85 Ų
H-Bond Donors25
H-Bond Acceptors75
Rotatable Bonds58
Heavy Atoms299
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004183.94
LogP ≤ 529.72
H-Bond Donors ≤ 525
H-Bond Acceptors ≤ 1075

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide with MolForge

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Related Compounds

5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 158064887
CID 158170789
CID 158170789
N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 158472702
CID 158547794
CID 158547794
5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperazin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperazin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 158606358
1-chloro-3-propan-2-ylbenzene;cumene;1-fluoro-3-propan-2-ylbenzene;5-fluoro-2-(4-propan-2-ylphenyl)pyrimidine;N-methyl-3-propan-2-ylbenzamide;1-methyl-4-propan-2-ylbenzene;2-methyl-5-(4-propan-2-ylphenyl)pyrimidine;bis(5-methyl-2-(4-propan-2-ylphenyl)pyrimidine);1-phenyl-4-propan-2-ylbenzene;3-(3-propan-2-ylphenyl)furan;2-(4-propan-2-ylphenyl)pyrazine;2-(4-propan-2-ylphenyl)pyridine;2-(4-propan-2-ylphenyl)pyrimidine;2-(4-propan-2-ylphenyl)-1,3-thiazole;2-(3-propan-2-ylphenyl)thiophene;3-(3-propan-2-ylphenyl)thiophene;1-propan-2-yl-3-(trifluoromethyl)benzene
CID 159026590
4-amino-6-(benzylamino)-8-chloro-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-1-one;3-(4-amino-1-phenylpyrazolo[3,4-d]pyrimidin-6-yl)sulfanylpropanamide;(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol;10-[(4-fluorophenyl)methyl]-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;2-propan-2-yl-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine;sulfane
CID 159794727
CID 160046775
CID 160046775
CID 160057999
CID 160057999
CID 160935476
CID 160935476
N-[(E)-[5-[3-chloro-4-(furan-2-yl)anilino]-2-pyridinyl]methylideneamino]-5-fluoro-4-morpholin-4-ylpyrimidin-2-amine;5-fluoro-N-[(E)-[5-(3-methyl-4-thiophen-2-ylanilino)-2-pyridinyl]methylideneamino]-4-morpholin-4-ylpyrimidin-2-amine;5-fluoro-N-[(E)-[5-(3-methyl-5-thiophen-3-ylanilino)-2-pyridinyl]methylideneamino]-4-morpholin-4-ylpyrimidin-2-amine;5-fluoro-4-morpholin-4-yl-N-[(E)-[5-(3-thiophen-2-ylanilino)-2-pyridinyl]methylideneamino]pyrimidin-2-amine;5-fluoro-4-morpholin-4-yl-N-[(E)-[5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]-2-pyridinyl]methylideneamino]pyrimidin-2-amine
CID 172919266
3-[[3-chloro-5-[[6-[(E)-[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)hydrazinylidene]methyl]-3-pyridinyl]amino]phenyl]methyl]phenol;N-[(E)-[5-[3-chloro-4-(furan-2-yl)anilino]-2-pyridinyl]methylideneamino]-5-fluoro-4-morpholin-4-ylpyrimidin-2-amine;5-fluoro-N-[(E)-[5-(3-methyl-4-thiophen-2-ylanilino)-2-pyridinyl]methylideneamino]-4-morpholin-4-ylpyrimidin-2-amine;5-fluoro-N-[(E)-[5-(3-methyl-5-thiophen-3-ylanilino)-2-pyridinyl]methylideneamino]-4-morpholin-4-ylpyrimidin-2-amine;3-[[3-[[6-[(E)-[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)hydrazinylidene]methyl]-3-pyridinyl]amino]phenyl]methyl]-5-methylphenol;3-[[3-[[6-[(E)-[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)hydrazinylidene]methyl]-3-pyridinyl]amino]-5-(trifluoromethyl)phenyl]methyl]phenol
CID 172927489

Frequently Asked Questions

What is the IUPAC name of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The IUPAC name of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide (CID 159782615) is 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide.
What is the SMILES notation for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The canonical SMILES for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide is CC1OCCC1c1cc(Cl)cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2ccco2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(-c2cncs2)c1.Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(C2CCSC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(-c3cccs3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(N3CCCCC3)cc(C(F)(F)F)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCCCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cccc(N3CCN(CCO)CC3)c2)cn1.
What is the InChIKey of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
The InChIKey is NHNWMMPDHNLGCM-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H28F4N8O2.C26H32FN9O3.C25H27ClFN7O3.C25H21F4N7O2S.C25H29FN8O2.C25H24FN7O3.C25H28FN7O2S.C24H23FN8O2S/c27-21-16-32-25(34-23(21)38-8-10-40-11-9-38)36-35-24(39)22-5-4-18(15-31-22)33-19-12-17(26(28,29)30)13-20(14-19)37-6-2-1-3-7-37;27-22-18-29-26(31-24(22)36-11-14-39-15-12-36)33-32-25(38)23-5-4-20(17-28-23)30-19-2-1-3-21(16-19)35-8-6-34(7-9-35)10-13-37;1-15-20(4-7-37-15)16-10-17(26)12-19(11-16)30-18-2-3-22(28-13-18)24(35)32-33-25-29-14-21(27)23(31-25)34-5-8-36-9-6-34;26-19-14-31-24(33-22(19)36-5-7-38-8-6-36)35-34-23(37)20-4-3-17(13-30-20)32-18-11-15(21-2-1-9-39-21)10-16(12-18)25(27,28)29;26-21-17-28-25(30-23(21)34-11-13-36-14-12-34)32-31-24(35)22-8-7-19(16-27-22)29-18-5-4-6-20(15-18)33-9-2-1-3-10-33;1-16-11-17(22-3-2-8-36-22)13-19(12-16)29-18-4-5-21(27-14-18)24(34)31-32-25-28-15-20(26)23(30-25)33-6-9-35-10-7-33;1-16-10-18(17-4-9-36-15-17)12-20(11-16)29-19-2-3-22(27-13-19)24(34)31-32-25-28-14-21(26)23(30-25)33-5-7-35-8-6-33;1-15-8-16(21-13-26-14-36-21)10-18(9-15)29-17-2-3-20(27-11-17)23(34)31-32-24-28-12-19(25)22(30-24)33-4-6-35-7-5-33/h4-5,12-16,33H,1-3,6-11H2,(H,35,39)(H,32,34,36);1-5,16-18,30,37H,6-15H2,(H,32,38)(H,29,31,33);2-3,10-15,20,30H,4-9H2,1H3,(H,32,35)(H,29,31,33);1-4,9-14,32H,5-8H2,(H,34,37)(H,31,33,35);4-8,15-17,29H,1-3,9-14H2,(H,31,35)(H,28,30,32);2-5,8,11-15,29H,6-7,9-10H2,1H3,(H,31,34)(H,28,30,32);2-3,10-14,17,29H,4-9,15H2,1H3,(H,31,34)(H,28,30,32);2-3,8-14,29H,4-7H2,1H3,(H,31,34)(H,28,30,32).
What are the key properties of 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide?
5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide has a molecular weight of 4183.94 g/mol, XLogP of 29.72, 58 rotatable bonds, 25 hydrogen bond donors, and 75 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-chloro-5-(2-methyloxolan-3-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-(furan-2-yl)-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(1,3-thiazol-5-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-methyl-5-(thiolan-3-yl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(3-piperidin-1-ylanilino)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-piperidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-thiophen-2-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide is sourced from PubChem (CID 159782615), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).