(2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide

C114H111Cl5F4N40O8 — CID 159783935

About (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide

(2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide (PubChem CID 159783935) has the molecular formula C114H111Cl5F4N40O8 and a molecular weight of 2422.67 g/mol. Its IUPAC name is (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide.

Molecular Properties

• Compound Name: (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide
• PubChem CID: 159783935
• Molecular Formula: C114H111Cl5F4N40O8
• Molecular Weight: 2422.67 g/mol
• Exact Mass: 2418.79
• IUPAC Name: (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide
• SMILES: C[C@@H]1CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C(N)=O)O1.C[C@@H]1CN(c2nccc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H](C(N)=O)O1.C[C@H]1CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](c2cn[nH]c2F)O1.Cc1[nH]ncc1[C@@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C)O1.Cc1[nH]ncc1[C@@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@H](C)O1.Cc1[nH]ncc1[C@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C)O1
• InChI: InChI=1S/3C20H20ClN7O.C19H17ClFN7O.C18H17F3N6O2.C17H17ClN6O2/c3*1-12-9-27(11-18(29-12)15-7-24-26-13(15)2)20-22-6-5-16(25-20)17-8-23-19-4-3-14(21)10-28(17)19;1-11-8-27(10-15(29-11)13-6-24-26-18(13)21)17-4-5-22-19(25-17)14-7-23-16-3-2-12(20)9-28(14)16;1-10-7-26(9-14(29-10)16(22)28)17-23-5-4-12(25-17)13-6-24-15-3-2-11(8-27(13)15)18(19,20)21;1-10-7-23(9-13(26-10)16(19)25)15-4-5-20-17(22-15)12-6-21-14-3-2-11(18)8-24(12)14/h3*3-8,10,12,18H,9,11H2,1-2H3,(H,24,26);2-7,9,11,15H,8,10H2,1H3,(H,24,26);2-6,8,10,14H,7,9H2,1H3,(H2,22,28);2-6,8,10,13H,7,9H2,1H3,(H2,19,25)/t12-,18+;2*12-,18-;11-,15-;10-,14-;10-,13+/m110011/s1
• InChIKey: NHSFULIKANRIQJ-GLYUVXDMSA-N
• XLogP: 17.01
• TPSA: 534.20 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 42
• Rotatable Bonds: 18
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2422.67
LogP ≤ 5	17.01
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide?

The IUPAC name of (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide (CID 159783935) is (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide.

What is the SMILES notation for (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide?

The canonical SMILES for (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide is C[C@@H]1CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C(N)=O)O1.C[C@@H]1CN(c2nccc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H](C(N)=O)O1.C[C@H]1CN(c2ccnc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](c2cn[nH]c2F)O1.Cc1[nH]ncc1[C@@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C)O1.Cc1[nH]ncc1[C@@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@H](C)O1.Cc1[nH]ncc1[C@H]1CN(c2nccc(-c3cnc4ccc(Cl)cn34)n2)C[C@@H](C)O1.

What is the InChIKey of (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide?

The InChIKey is NHSFULIKANRIQJ-GLYUVXDMSA-N. The full InChI is InChI=1S/3C20H20ClN7O.C19H17ClFN7O.C18H17F3N6O2.C17H17ClN6O2/c3*1-12-9-27(11-18(29-12)15-7-24-26-13(15)2)20-22-6-5-16(25-20)17-8-23-19-4-3-14(21)10-28(17)19;1-11-8-27(10-15(29-11)13-6-24-26-18(13)21)17-4-5-22-19(25-17)14-7-23-16-3-2-12(20)9-28(14)16;1-10-7-26(9-14(29-10)16(22)28)17-23-5-4-12(25-17)13-6-24-15-3-2-11(8-27(13)15)18(19,20)21;1-10-7-23(9-13(26-10)16(19)25)15-4-5-20-17(22-15)12-6-21-14-3-2-11(18)8-24(12)14/h3*3-8,10,12,18H,9,11H2,1-2H3,(H,24,26);2-7,9,11,15H,8,10H2,1H3,(H,24,26);2-6,8,10,14H,7,9H2,1H3,(H2,22,28);2-6,8,10,13H,7,9H2,1H3,(H2,19,25)/t12-,18+;2*12-,18-;11-,15-;10-,14-;10-,13+/m110011/s1.

What are the key properties of (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide?

(2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide has a molecular weight of 2422.67 g/mol, XLogP of 17.01, 18 rotatable bonds, 6 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,6S)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-2-(5-fluoro-1H-pyrazol-4-yl)-6-methylmorpholine;(2R,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[2-(6-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-4-yl]-6-methylmorpholine-2-carboxamide;(2R,6R)-6-methyl-4-[4-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]morpholine-2-carboxamide is sourced from PubChem (CID 159783935), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).