(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid

C116H110Cl2F16N36O8 — CID 157381261

About (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid

(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid (PubChem CID 157381261) has the molecular formula C116H110Cl2F16N36O8 and a molecular weight of 2511.27 g/mol. Its IUPAC name is (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid.

Molecular Properties

• Compound Name: (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid
• PubChem CID: 157381261
• Molecular Formula: C116H110Cl2F16N36O8
• Molecular Weight: 2511.27 g/mol
• Exact Mass: 2508.84
• IUPAC Name: (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid
• SMILES: CC1CCC(C(=O)O)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.CC1CCC(C(N)=O)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.Cc1cnc(N2C[C@@H](C)O[C@@H](c3cn[nH]c3C)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@@H](c3cn[nH]c3C)O[C@@H](C)C2)nc1-c1cnc2ccc(Cl)cn12.NC(=O)C1CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CC(F)(F)C1.O=C(O)C1CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CC(F)(F)C1
• InChI: InChI=1S/2C21H22ClN7O.C19H19F3N6O.C19H18F3N5O2.C18H15F5N6O.C18H14F5N5O2/c2*1-12-6-24-21(26-20(12)17-8-23-19-5-4-15(22)10-29(17)19)28-9-13(2)30-18(11-28)16-7-25-27-14(16)3;1-11-2-3-12(17(23)29)9-27(11)16-6-7-24-18(26-16)14-8-25-15-5-4-13(10-28(14)15)19(20,21)22;1-11-2-3-12(18(28)29)9-26(11)16-6-7-23-17(25-16)14-8-24-15-5-4-13(10-27(14)15)19(20,21)22;19-17(20)5-10(15(24)30)7-28(9-17)14-3-4-25-16(27-14)12-6-26-13-2-1-11(8-29(12)13)18(21,22)23;19-17(20)5-10(16(29)30)7-27(9-17)14-3-4-24-15(26-14)12-6-25-13-2-1-11(8-28(12)13)18(21,22)23/h2*4-8,10,13,18H,9,11H2,1-3H3,(H,25,27);4-8,10-12H,2-3,9H2,1H3,(H2,23,29);4-8,10-12H,2-3,9H2,1H3,(H,28,29);1-4,6,8,10H,5,7,9H2,(H2,24,30);1-4,6,8,10H,5,7,9H2,(H,29,30)/t2*13-,18-;;;;/m10..../s1
• InChIKey: BKXHVYORNZFCNH-XVRRDRJUSA-N
• XLogP: 20.02
• TPSA: 514.52 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 38
• Rotatable Bonds: 18
• Heavy Atoms: 178
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2511.27
LogP ≤ 5	20.02
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	38

Frequently Asked Questions

What is the IUPAC name of (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid?

The IUPAC name of (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid (CID 157381261) is (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid.

What is the SMILES notation for (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid?

The canonical SMILES for (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid is CC1CCC(C(=O)O)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.CC1CCC(C(N)=O)CN1c1ccnc(-c2cnc3ccc(C(F)(F)F)cn23)n1.Cc1cnc(N2C[C@@H](C)O[C@@H](c3cn[nH]c3C)C2)nc1-c1cnc2ccc(Cl)cn12.Cc1cnc(N2C[C@@H](c3cn[nH]c3C)O[C@@H](C)C2)nc1-c1cnc2ccc(Cl)cn12.NC(=O)C1CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CC(F)(F)C1.O=C(O)C1CN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)CC(F)(F)C1.

What is the InChIKey of (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid?

The InChIKey is BKXHVYORNZFCNH-XVRRDRJUSA-N. The full InChI is InChI=1S/2C21H22ClN7O.C19H19F3N6O.C19H18F3N5O2.C18H15F5N6O.C18H14F5N5O2/c2*1-12-6-24-21(26-20(12)17-8-23-19-5-4-15(22)10-29(17)19)28-9-13(2)30-18(11-28)16-7-25-27-14(16)3;1-11-2-3-12(17(23)29)9-27(11)16-6-7-24-18(26-16)14-8-25-15-5-4-13(10-28(14)15)19(20,21)22;1-11-2-3-12(18(28)29)9-26(11)16-6-7-23-17(25-16)14-8-24-15-5-4-13(10-27(14)15)19(20,21)22;19-17(20)5-10(15(24)30)7-28(9-17)14-3-4-25-16(27-14)12-6-26-13-2-1-11(8-29(12)13)18(21,22)23;19-17(20)5-10(16(29)30)7-27(9-17)14-3-4-24-15(26-14)12-6-25-13-2-1-11(8-28(12)13)18(21,22)23/h2*4-8,10,13,18H,9,11H2,1-3H3,(H,25,27);4-8,10-12H,2-3,9H2,1H3,(H2,23,29);4-8,10-12H,2-3,9H2,1H3,(H,28,29);1-4,6,8,10H,5,7,9H2,(H2,24,30);1-4,6,8,10H,5,7,9H2,(H,29,30)/t2*13-,18-;;;;/m10..../s1.

What are the key properties of (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid?

(2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid has a molecular weight of 2511.27 g/mol, XLogP of 20.02, 18 rotatable bonds, 6 hydrogen bond donors, and 38 hydrogen bond acceptors.

Where does this data come from?

All data for (2R,6S)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;(2S,6R)-4-[4-(6-chloroimidazo[1,2-a]pyridin-3-yl)-5-methylpyrimidin-2-yl]-2-methyl-6-(5-methyl-1H-pyrazol-4-yl)morpholine;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;5,5-difluoro-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxamide;6-methyl-1-[2-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]piperidine-3-carboxylic acid is sourced from PubChem (CID 157381261), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).