(1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

C103H123F5N26O7 — CID 159803681

About (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

(1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (PubChem CID 159803681) has the molecular formula C103H123F5N26O7 and a molecular weight of 1932.28 g/mol. Its IUPAC name is (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

Molecular Properties

• Compound Name: (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
• PubChem CID: 159803681
• Molecular Formula: C103H123F5N26O7
• Molecular Weight: 1932.28 g/mol
• Exact Mass: 1931.00
• IUPAC Name: (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
• SMILES: CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C#N)c2ccccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C(F)(F)F)c2c(F)cccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C2=CCOCC2)c2ccccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(F)cccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2cnccn12.Cc1cccn2c(C(C)(C)NC(=O)C3[C@H]4CNC[C@@H]34)ncc12
• InChI: InChI=1S/C21H26N4O2.C17H18F4N4O.C17H19N5O.C17H22N4O.C16H19FN4O.C15H19N5O/c1-21(2,24-19(26)17-14-11-22-12-15(14)17)20-23-18(13-6-9-27-10-7-13)16-5-3-4-8-25(16)20;1-16(2,24-14(26)11-8-6-22-7-9(8)11)15-23-13(17(19,20)21)12-10(18)4-3-5-25(12)15;1-17(2,21-15(23)14-10-8-19-9-11(10)14)16-20-12(7-18)13-5-3-4-6-22(13)16;1-10-5-4-6-21-13(10)9-19-16(21)17(2,3)20-15(22)14-11-7-18-8-12(11)14;1-16(2,20-14(22)13-9-6-18-7-10(9)13)15-19-8-12-11(17)4-3-5-21(12)15;1-15(2,14-18-6-9-5-16-3-4-20(9)14)19-13(21)12-10-7-17-8-11(10)12/h3-6,8,14-15,17,22H,7,9-12H2,1-2H3,(H,24,26);3-5,8-9,11,22H,6-7H2,1-2H3,(H,24,26);3-6,10-11,14,19H,8-9H2,1-2H3,(H,21,23);4-6,9,11-12,14,18H,7-8H2,1-3H3,(H,20,22);3-5,8-10,13,18H,6-7H2,1-2H3,(H,20,22);3-6,10-12,17H,7-8H2,1-2H3,(H,19,21)/t14-,15+,17?;8-,9+,11?;10-,11+,14?;11-,12+,14?;9-,10+,13?;10-,11+,12?
• InChIKey: NKCOZUNINIGRLN-LNVHBOGVSA-N
• XLogP: 8.58
• TPSA: 396.49 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 27
• Rotatable Bonds: 19
• Heavy Atoms: 141
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1932.28
LogP ≤ 5	8.58
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The IUPAC name of (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (CID 159803681) is (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

What is the SMILES notation for (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The canonical SMILES for (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C#N)c2ccccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C(F)(F)F)c2c(F)cccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1nc(C2=CCOCC2)c2ccccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2c(F)cccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2cnccn12.Cc1cccn2c(C(C)(C)NC(=O)C3[C@H]4CNC[C@@H]34)ncc12.

What is the InChIKey of (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

The InChIKey is NKCOZUNINIGRLN-LNVHBOGVSA-N. The full InChI is InChI=1S/C21H26N4O2.C17H18F4N4O.C17H19N5O.C17H22N4O.C16H19FN4O.C15H19N5O/c1-21(2,24-19(26)17-14-11-22-12-15(14)17)20-23-18(13-6-9-27-10-7-13)16-5-3-4-8-25(16)20;1-16(2,24-14(26)11-8-6-22-7-9(8)11)15-23-13(17(19,20)21)12-10(18)4-3-5-25(12)15;1-17(2,21-15(23)14-10-8-19-9-11(10)14)16-20-12(7-18)13-5-3-4-6-22(13)16;1-10-5-4-6-21-13(10)9-19-16(21)17(2,3)20-15(22)14-11-7-18-8-12(11)14;1-16(2,20-14(22)13-9-6-18-7-10(9)13)15-19-8-12-11(17)4-3-5-21(12)15;1-15(2,14-18-6-9-5-16-3-4-20(9)14)19-13(21)12-10-7-17-8-11(10)12/h3-6,8,14-15,17,22H,7,9-12H2,1-2H3,(H,24,26);3-5,8-9,11,22H,6-7H2,1-2H3,(H,24,26);3-6,10-11,14,19H,8-9H2,1-2H3,(H,21,23);4-6,9,11-12,14,18H,7-8H2,1-3H3,(H,20,22);3-5,8-10,13,18H,6-7H2,1-2H3,(H,20,22);3-6,10-12,17H,7-8H2,1-2H3,(H,19,21)/t14-,15+,17?;8-,9+,11?;10-,11+,14?;11-,12+,14?;9-,10+,13?;10-,11+,12?.

What are the key properties of (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?

(1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide has a molecular weight of 1932.28 g/mol, XLogP of 8.58, 19 rotatable bonds, 12 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for (1R,5S)-N-[2-(1-cyanoimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[1-(3,6-dihydro-2H-pyran-4-yl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-fluoroimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[8-fluoro-1-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-(2-imidazo[1,5-a]pyrazin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is sourced from PubChem (CID 159803681), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).