2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one

C146H126N38O8 — CID 161422128

About 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one

2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one (PubChem CID 161422128) has the molecular formula C146H126N38O8 and a molecular weight of 2540.87 g/mol. Its IUPAC name is 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one.

Molecular Properties

• Compound Name: 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one
• PubChem CID: 161422128
• Molecular Formula: C146H126N38O8
• Molecular Weight: 2540.87 g/mol
• Exact Mass: 2539.06
• IUPAC Name: 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one
• SMILES: Cc1cc(-c2c(C#N)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2c(C)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2cnc3c(ccn3CC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(C3=CCOCC3)ccnc21.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(C3CCOCC3)ccnc21.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(N3CCCCC3)ccnc21
• InChI: InChI=1S/C25H18N8O.C25H21N7O.C24H19N7O.C24H24N6O.C24H23N5O2.C24H21N5O2/c1-16-10-17(4-6-28-16)24-19(11-26)13-31-25-20(24)5-9-33(25)15-23(34)32-22-3-2-18(12-30-22)21-14-27-7-8-29-21;1-16-12-30-25-20(24(16)18-5-7-27-17(2)11-18)6-10-32(25)15-23(33)31-22-4-3-19(13-29-22)21-14-26-8-9-28-21;1-16-10-17(4-6-26-16)20-11-18-5-9-31(24(18)29-13-20)15-23(32)30-22-3-2-19(12-28-22)21-14-25-7-8-27-21;31-20(14-19-5-4-18(15-28-19)22-16-25-9-10-26-22)17-30-13-7-21-23(6-8-27-24(21)30)29-11-2-1-3-12-29;2*30-20(13-19-2-1-18(14-28-19)23-15-25-8-9-26-23)16-29-10-4-22-21(3-7-27-24(22)29)17-5-11-31-12-6-17/h2-10,12-14H,15H2,1H3,(H,30,32,34);3-14H,15H2,1-2H3,(H,29,31,33);2-14H,15H2,1H3,(H,28,30,32);4-10,13,15-16H,1-3,11-12,14,17H2;1-4,7-10,14-15,17H,5-6,11-13,16H2;1-5,7-10,14-15H,6,11-13,16H2
• InChIKey: VWWIXQZLQPTDPL-UHFFFAOYSA-N
• XLogP: 22.66
• TPSA: 561.61 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 43
• Rotatable Bonds: 33
• Heavy Atoms: 192
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2540.87
LogP ≤ 5	22.66
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one?

The IUPAC name of 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one (CID 161422128) is 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one.

What is the SMILES notation for 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one?

The canonical SMILES for 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one is Cc1cc(-c2c(C#N)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2c(C)cnc3c2ccn3CC(=O)Nc2ccc(-c3cnccn3)cn2)ccn1.Cc1cc(-c2cnc3c(ccn3CC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(C3=CCOCC3)ccnc21.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(C3CCOCC3)ccnc21.O=C(Cc1ccc(-c2cnccn2)cn1)Cn1ccc2c(N3CCCCC3)ccnc21.

What is the InChIKey of 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one?

The InChIKey is VWWIXQZLQPTDPL-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H18N8O.C25H21N7O.C24H19N7O.C24H24N6O.C24H23N5O2.C24H21N5O2/c1-16-10-17(4-6-28-16)24-19(11-26)13-31-25-20(24)5-9-33(25)15-23(34)32-22-3-2-18(12-30-22)21-14-27-7-8-29-21;1-16-12-30-25-20(24(16)18-5-7-27-17(2)11-18)6-10-32(25)15-23(33)31-22-4-3-19(13-29-22)21-14-26-8-9-28-21;1-16-10-17(4-6-26-16)20-11-18-5-9-31(24(18)29-13-20)15-23(32)30-22-3-2-19(12-28-22)21-14-25-7-8-27-21;31-20(14-19-5-4-18(15-28-19)22-16-25-9-10-26-22)17-30-13-7-21-23(6-8-27-24(21)30)29-11-2-1-3-12-29;2*30-20(13-19-2-1-18(14-28-19)23-15-25-8-9-26-23)16-29-10-4-22-21(3-7-27-24(22)29)17-5-11-31-12-6-17/h2-10,12-14H,15H2,1H3,(H,30,32,34);3-14H,15H2,1-2H3,(H,29,31,33);2-14H,15H2,1H3,(H,28,30,32);4-10,13,15-16H,1-3,11-12,14,17H2;1-4,7-10,14-15,17H,5-6,11-13,16H2;1-5,7-10,14-15H,6,11-13,16H2.

What are the key properties of 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one?

2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one has a molecular weight of 2540.87 g/mol, XLogP of 22.66, 33 rotatable bonds, 3 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[5-cyano-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(3,6-dihydro-2H-pyran-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;2-[5-methyl-4-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;2-[5-(2-methyl-4-pyridinyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide;1-[4-(oxan-4-yl)pyrrolo[2,3-b]pyridin-1-yl]-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one;1-(4-piperidin-1-ylpyrrolo[2,3-b]pyridin-1-yl)-3-(5-pyrazin-2-yl-2-pyridinyl)propan-2-one is sourced from PubChem (CID 161422128), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).