6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C119H102F21N25O15 — CID 159825201

About 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 159825201) has the molecular formula C119H102F21N25O15 and a molecular weight of 2521.24 g/mol. Its IUPAC name is 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

• Compound Name: 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• PubChem CID: 159825201
• Molecular Formula: C119H102F21N25O15
• Molecular Weight: 2521.24 g/mol
• Exact Mass: 2519.77
• IUPAC Name: 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• SMILES: CC1(O)COCC1(NC(=O)c1cnn2cc(C3CC3)cnc12)c1ccc(C(F)(F)F)nc1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4)COC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4F)COC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)nc4)COCC3(C)O)cnn2c1.O=C(CC1(c2ccc(C(F)(F)F)cc2F)CCOCC1=O)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(C(F)(F)F)cc2F)COC1)c1cnn2cc(C3CC3)cnc12
• InChI: InChI=1S/C23H19F4N3O3.C21H20F3N5O3.C20H16F4N4O2.C19H18F3N5O3.C18H14F4N4O2.C18H15F3N4O2/c24-18-7-15(23(25,26)27)3-4-17(18)22(5-6-33-12-20(22)32)8-19(31)16-10-29-30-11-14(13-1-2-13)9-28-21(16)30;1-19(31)10-32-11-20(19,14-4-5-16(25-7-14)21(22,23)24)28-18(30)15-8-27-29-9-13(12-2-3-12)6-26-17(15)29;21-16-5-13(20(22,23)24)3-4-15(16)19(9-30-10-19)27-18(29)14-7-26-28-8-12(11-1-2-11)6-25-17(14)28;1-11-5-24-15-13(7-25-27(15)8-11)16(28)26-18(10-30-9-17(18,2)29)12-3-4-14(23-6-12)19(20,21)22;1-10-5-23-15-12(6-24-26(15)7-10)16(27)25-17(8-28-9-17)13-3-2-11(4-14(13)19)18(20,21)22;1-11-6-22-15-14(7-23-25(15)8-11)16(26)24-17(9-27-10-17)12-2-4-13(5-3-12)18(19,20)21/h3-4,7,9-11,13H,1-2,5-6,8,12H2;4-9,12,31H,2-3,10-11H2,1H3,(H,28,30);3-8,11H,1-2,9-10H2,(H,27,29);3-8,29H,9-10H2,1-2H3,(H,26,28);2-7H,8-9H2,1H3,(H,25,27);2-8H,9-10H2,1H3,(H,24,26)
• InChIKey: NMTBWHMMEWWSJY-UHFFFAOYSA-N
• XLogP: 17.53
• TPSA: 482.40 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 35
• Rotatable Bonds: 22
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2521.24
LogP ≤ 5	17.53
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The IUPAC name of 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 159825201) is 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

What is the SMILES notation for 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The canonical SMILES for 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is CC1(O)COCC1(NC(=O)c1cnn2cc(C3CC3)cnc12)c1ccc(C(F)(F)F)nc1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4)COC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)cc4F)COC3)cnn2c1.Cc1cnc2c(C(=O)NC3(c4ccc(C(F)(F)F)nc4)COCC3(C)O)cnn2c1.O=C(CC1(c2ccc(C(F)(F)F)cc2F)CCOCC1=O)c1cnn2cc(C3CC3)cnc12.O=C(NC1(c2ccc(C(F)(F)F)cc2F)COC1)c1cnn2cc(C3CC3)cnc12.

What is the InChIKey of 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The InChIKey is NMTBWHMMEWWSJY-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H19F4N3O3.C21H20F3N5O3.C20H16F4N4O2.C19H18F3N5O3.C18H14F4N4O2.C18H15F3N4O2/c24-18-7-15(23(25,26)27)3-4-17(18)22(5-6-33-12-20(22)32)8-19(31)16-10-29-30-11-14(13-1-2-13)9-28-21(16)30;1-19(31)10-32-11-20(19,14-4-5-16(25-7-14)21(22,23)24)28-18(30)15-8-27-29-9-13(12-2-3-12)6-26-17(15)29;21-16-5-13(20(22,23)24)3-4-15(16)19(9-30-10-19)27-18(29)14-7-26-28-8-12(11-1-2-11)6-25-17(14)28;1-11-5-24-15-13(7-25-27(15)8-11)16(28)26-18(10-30-9-17(18,2)29)12-3-4-14(23-6-12)19(20,21)22;1-10-5-23-15-12(6-24-26(15)7-10)16(27)25-17(8-28-9-17)13-3-2-11(4-14(13)19)18(20,21)22;1-11-6-22-15-14(7-23-25(15)8-11)16(26)24-17(9-27-10-17)12-2-4-13(5-3-12)18(19,20)21/h3-4,7,9-11,13H,1-2,5-6,8,12H2;4-9,12,31H,2-3,10-11H2,1H3,(H,28,30);3-8,11H,1-2,9-10H2,(H,27,29);3-8,29H,9-10H2,1-2H3,(H,26,28);2-7H,8-9H2,1H3,(H,25,27);2-8H,9-10H2,1H3,(H,24,26).

What are the key properties of 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2521.24 g/mol, XLogP of 17.53, 22 rotatable bonds, 7 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 6-cyclopropyl-N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;4-[2-(6-cyclopropylpyrazolo[1,5-a]pyrimidin-3-yl)-2-oxoethyl]-4-[2-fluoro-4-(trifluoromethyl)phenyl]oxan-3-one;N-[3-[2-fluoro-4-(trifluoromethyl)phenyl]oxetan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[4-hydroxy-4-methyl-3-[6-(trifluoromethyl)-3-pyridinyl]oxolan-3-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-methyl-N-[3-[4-(trifluoromethyl)phenyl]oxetan-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 159825201), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).