3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide

C156H151F12N31O13S2 — CID 159868549

IUPAC3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide
SMILESCc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(-c2cnn(C)c2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ncc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1
InChIInChI=1S/C28H25F3N6O.2C28H28F3N5O2.C27H27F3N6O2.C23H22N4O3S.C22H21N5O3S/c1-16-5-6-23(36-26(38)17-8-21(27(2,3)33)10-22(9-17)28(29,30)31)11-24(16)19-7-18(12-32)25(34-13-19)20-14-35-37(4)15-20;1-16-5-6-22(35-25(37)17-8-20(26(2,3)33)10-21(9-17)28(29,30)31)11-23(16)19-7-18(12-32)24(34-13-19)36-14-27(4,38)15-36;1-17-4-5-23(35-26(37)18-11-21(27(2,3)33)13-22(12-18)28(29,30)31)14-24(17)20-10-19(15-32)25(34-16-20)36-6-8-38-9-7-36;1-15-22(18-5-17(10-31)23(34-11-18)36-13-26(4,38)14-36)9-21(12-33-15)35-24(37)16-6-19(25(2,3)32)8-20(7-16)27(28,29)30;1-15-8-9-19(26-23(28)16-6-5-7-20(11-16)31(4,29)30)12-21(15)18-10-17(13-24)22(25-14-18)27(2)3;1-14-20(17-8-16(11-23)21(25-12-17)27(2)3)10-18(13-24-14)26-22(28)15-6-5-7-19(9-15)31(4,29)30/h5-11,13-15H,33H2,1-4H3,(H,36,38);5-11,13,38H,14-15,33H2,1-4H3,(H,35,37);4-5,10-14,16H,6-9,33H2,1-3H3,(H,35,37);5-9,11-12,38H,13-14,32H2,1-4H3,(H,35,37);5-12,14H,1-4H3,(H,26,28);5-10,12-13H,1-4H3,(H,26,28)
InChIKeyNSARDNWXIQDWCJ-UHFFFAOYSA-N
MW2960.24 g/mol
LogP27.04
Rot. Bonds30

About 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide

3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide (PubChem CID 159868549) has the molecular formula C156H151F12N31O13S2 and a molecular weight of 2960.24 g/mol. Its IUPAC name is 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide.

Molecular Properties

Compound Name3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide
PubChem CID159868549
Molecular FormulaC156H151F12N31O13S2
Molecular Weight2960.24 g/mol
Exact Mass2958.14
IUPAC Name3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide
SMILESCc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(-c2cnn(C)c2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ncc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1
InChIInChI=1S/C28H25F3N6O.2C28H28F3N5O2.C27H27F3N6O2.C23H22N4O3S.C22H21N5O3S/c1-16-5-6-23(36-26(38)17-8-21(27(2,3)33)10-22(9-17)28(29,30)31)11-24(16)19-7-18(12-32)25(34-13-19)20-14-35-37(4)15-20;1-16-5-6-22(35-25(37)17-8-20(26(2,3)33)10-21(9-17)28(29,30)31)11-23(16)19-7-18(12-32)24(34-13-19)36-14-27(4,38)15-36;1-17-4-5-23(35-26(37)18-11-21(27(2,3)33)13-22(12-18)28(29,30)31)14-24(17)20-10-19(15-32)25(34-16-20)36-6-8-38-9-7-36;1-15-22(18-5-17(10-31)23(34-11-18)36-13-26(4,38)14-36)9-21(12-33-15)35-24(37)16-6-19(25(2,3)32)8-20(7-16)27(28,29)30;1-15-8-9-19(26-23(28)16-6-5-7-20(11-16)31(4,29)30)12-21(15)18-10-17(13-24)22(25-14-18)27(2)3;1-14-20(17-8-16(11-23)21(25-12-17)27(2)3)10-18(13-24-14)26-22(28)15-6-5-7-19(9-15)31(4,29)30/h5-11,13-15H,33H2,1-4H3,(H,36,38);5-11,13,38H,14-15,33H2,1-4H3,(H,35,37);4-5,10-14,16H,6-9,33H2,1-3H3,(H,35,37);5-9,11-12,38H,13-14,32H2,1-4H3,(H,35,37);5-12,14H,1-4H3,(H,26,28);5-10,12-13H,1-4H3,(H,26,28)
InChIKeyNSARDNWXIQDWCJ-UHFFFAOYSA-N
XLogP27.04
TPSA676.53 Ų
H-Bond Donors12
H-Bond Acceptors38
Rotatable Bonds30
Heavy Atoms214
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002960.24
LogP ≤ 527.04
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1038

Analyze 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-2-ethyl-3-oxo-4-(trifluoromethyl)-2H-pyridine-6-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157313884
3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1,3-dimethylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[5-[5-cyano-6-(3-hydroxyazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-[5-cyano-6-(oxan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(4-oxo-1-pyridinyl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[5-(5-cyano-6-pyridin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157623051
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)pyridine-3-carboxamide
CID 157707307
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 157782406
3-(2-aminopropan-2-yl)-N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-3-methylbenzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylbenzamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide
CID 158655694
2-(1-cyanocyclopropyl)-N-[3-[2-(3-hydroxyazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;6-cyclopropyl-N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridazine-4-carboxamide;5-(difluoromethyl)-N-[3-[2-(3-hydroxyazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridazine-4-carboxamide;2-(difluoromethyl)-N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 158989334
3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;methane
CID 159428896
3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide
CID 159745604
3-(2-aminopropan-2-yl)-N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide;N-[5-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(difluoromethyl)benzamide
CID 159981420
N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-1,3-dimethylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methyl-1-propan-2-ylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 160068732
2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 161245978
6-cyclopropyl-N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridazine-4-carboxamide;5-(difluoromethyl)-N-[3-[2-(3-hydroxyazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridazine-4-carboxamide;2-(difluoromethyl)-N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-methylsulfonylpyridazine-4-carboxamide;N-[3-[2-(3-hydroxy-3-methylazetidin-1-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide
CID 161396932

Frequently Asked Questions

What is the IUPAC name of 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide?
The IUPAC name of 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide (CID 159868549) is 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide.
What is the SMILES notation for 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide?
The canonical SMILES for 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide is Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(-c2cnn(C)c2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ccc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1.Cc1ncc(NC(=O)c2cc(C(C)(C)N)cc(C(F)(F)F)c2)cc1-c1cnc(N2CC(C)(O)C2)c(C#N)c1.Cc1ncc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1cnc(N(C)C)c(C#N)c1.
What is the InChIKey of 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide?
The InChIKey is NSARDNWXIQDWCJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H25F3N6O.2C28H28F3N5O2.C27H27F3N6O2.C23H22N4O3S.C22H21N5O3S/c1-16-5-6-23(36-26(38)17-8-21(27(2,3)33)10-22(9-17)28(29,30)31)11-24(16)19-7-18(12-32)25(34-13-19)20-14-35-37(4)15-20;1-16-5-6-22(35-25(37)17-8-20(26(2,3)33)10-21(9-17)28(29,30)31)11-23(16)19-7-18(12-32)24(34-13-19)36-14-27(4,38)15-36;1-17-4-5-23(35-26(37)18-11-21(27(2,3)33)13-22(12-18)28(29,30)31)14-24(17)20-10-19(15-32)25(34-16-20)36-6-8-38-9-7-36;1-15-22(18-5-17(10-31)23(34-11-18)36-13-26(4,38)14-36)9-21(12-33-15)35-24(37)16-6-19(25(2,3)32)8-20(7-16)27(28,29)30;1-15-8-9-19(26-23(28)16-6-5-7-20(11-16)31(4,29)30)12-21(15)18-10-17(13-24)22(25-14-18)27(2)3;1-14-20(17-8-16(11-23)21(25-12-17)27(2)3)10-18(13-24-14)26-22(28)15-6-5-7-19(9-15)31(4,29)30/h5-11,13-15H,33H2,1-4H3,(H,36,38);5-11,13,38H,14-15,33H2,1-4H3,(H,35,37);4-5,10-14,16H,6-9,33H2,1-3H3,(H,35,37);5-9,11-12,38H,13-14,32H2,1-4H3,(H,35,37);5-12,14H,1-4H3,(H,26,28);5-10,12-13H,1-4H3,(H,26,28).
What are the key properties of 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide?
3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide has a molecular weight of 2960.24 g/mol, XLogP of 27.04, 30 rotatable bonds, 12 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[5-[5-cyano-6-(3-hydroxy-3-methylazetidin-1-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-[5-cyano-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)benzamide;3-(2-aminopropan-2-yl)-N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(dimethylamino)-3-pyridinyl]-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide is sourced from PubChem (CID 159868549), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).