2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

C138H146F9N31O16S — CID 161245978

About 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide

2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 161245978) has the molecular formula C138H146F9N31O16S and a molecular weight of 2697.94 g/mol. Its IUPAC name is 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

Molecular Properties

• Compound Name: 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
• PubChem CID: 161245978
• Molecular Formula: C138H146F9N31O16S
• Molecular Weight: 2697.94 g/mol
• Exact Mass: 2696.11
• IUPAC Name: 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
• SMILES: CCn1cc(C(=O)Nc2cnc(C)c(-c3cc(N4CCOCC4)nc(N4CCOCC4)c3)c2)cc(C(F)(F)F)c1=O.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(-c2c(C)n[nH]c2C)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(-c2cnn(C)c2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1
• InChI: InChI=1S/C29H33N7O3.C28H31F3N6O4.C28H27F3N6O2.C27H25F3N6O2.C26H30N6O5S/c1-20-24(17-23(18-32-20)33-28(37)21-4-5-31-25(14-21)29(2,3)19-30)22-15-26(35-6-10-38-11-7-35)34-27(16-22)36-8-12-39-13-9-36;1-3-35-17-20(12-23(27(35)39)28(29,30)31)26(38)33-21-15-22(18(2)32-16-21)19-13-24(36-4-8-40-9-5-36)34-25(14-19)37-6-10-41-11-7-37;1-16-4-5-21(33-27(38)19-6-7-32-24(13-19)28(29,30)31)15-22(16)20-12-23(26-17(2)35-36-18(26)3)34-25(14-20)37-8-10-39-11-9-37;1-17-3-4-21(33-26(37)18-5-6-31-24(12-18)27(28,29)30)14-22(17)19-11-23(20-15-32-35(2)16-20)34-25(13-19)36-7-9-38-10-8-36;1-18-22(16-21(17-28-18)29-26(33)19-3-4-27-25(15-19)38(2,34)35)20-13-23(31-5-9-36-10-6-31)30-24(14-20)32-7-11-37-12-8-32/h4-5,14-18H,6-13H2,1-3H3,(H,33,37);12-17H,3-11H2,1-2H3,(H,33,38);4-7,12-15H,8-11H2,1-3H3,(H,33,38)(H,35,36);3-6,11-16H,7-10H2,1-2H3,(H,33,37);3-4,13-17H,5-12H2,1-2H3,(H,29,33)
• InChIKey: VAQJYLYFKAAIJL-UHFFFAOYSA-N
• XLogP: 19.85
• TPSA: 526.37 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 41
• Rotatable Bonds: 28
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2697.94
LogP ≤ 5	19.85
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The IUPAC name of 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 161245978) is 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

What is the SMILES notation for 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The canonical SMILES for 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is CCn1cc(C(=O)Nc2cnc(C)c(-c3cc(N4CCOCC4)nc(N4CCOCC4)c3)c2)cc(C(F)(F)F)c1=O.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(-c2c(C)n[nH]c2C)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(-c2cnn(C)c2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.

What is the InChIKey of 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The InChIKey is VAQJYLYFKAAIJL-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H33N7O3.C28H31F3N6O4.C28H27F3N6O2.C27H25F3N6O2.C26H30N6O5S/c1-20-24(17-23(18-32-20)33-28(37)21-4-5-31-25(14-21)29(2,3)19-30)22-15-26(35-6-10-38-11-7-35)34-27(16-22)36-8-12-39-13-9-36;1-3-35-17-20(12-23(27(35)39)28(29,30)31)26(38)33-21-15-22(18(2)32-16-21)19-13-24(36-4-8-40-9-5-36)34-25(14-19)37-6-10-41-11-7-37;1-16-4-5-21(33-27(38)19-6-7-32-24(13-19)28(29,30)31)15-22(16)20-12-23(26-17(2)35-36-18(26)3)34-25(14-20)37-8-10-39-11-9-37;1-17-3-4-21(33-26(37)18-5-6-31-24(12-18)27(28,29)30)14-22(17)19-11-23(20-15-32-35(2)16-20)34-25(13-19)36-7-9-38-10-8-36;1-18-22(16-21(17-28-18)29-26(33)19-3-4-27-25(15-19)38(2,34)35)20-13-23(31-5-9-36-10-6-31)30-24(14-20)32-7-11-37-12-8-32/h4-5,14-18H,6-13H2,1-3H3,(H,33,37);12-17H,3-11H2,1-2H3,(H,33,38);4-7,12-15H,8-11H2,1-3H3,(H,33,38)(H,35,36);3-6,11-16H,7-10H2,1-2H3,(H,33,37);3-4,13-17H,5-12H2,1-2H3,(H,29,33).

What are the key properties of 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 2697.94 g/mol, XLogP of 19.85, 28 rotatable bonds, 6 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(2-cyanopropan-2-yl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[2-(3,5-dimethyl-1H-pyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-1-ethyl-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide;N-[4-methyl-3-[2-(1-methylpyrazol-4-yl)-6-morpholin-4-yl-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 161245978), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).