3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide

C134H149F7N28O17S — CID 158714524

About 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide

3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 158714524) has the molecular formula C134H149F7N28O17S and a molecular weight of 2588.90 g/mol. Its IUPAC name is 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

Molecular Properties

• Compound Name: 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
• PubChem CID: 158714524
• Molecular Formula: C134H149F7N28O17S
• Molecular Weight: 2588.90 g/mol
• Exact Mass: 2587.13
• IUPAC Name: 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
• SMILES: Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)C)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1
• InChI: InChI=1S/C28H34N6O3.C27H29F2N5O3.C27H31N5O5S.C26H27F3N6O3.C26H28F2N6O3/c1-19(2)25-14-21(4-5-29-25)28(35)31-23-17-24(20(3)30-18-23)22-15-26(33-6-10-36-11-7-33)32-27(16-22)34-8-12-37-13-9-34;1-18-23(16-22(17-30-18)31-27(35)20-4-2-3-19(13-20)26(28)29)21-14-24(33-5-9-36-10-6-33)32-25(15-21)34-7-11-37-12-8-34;1-19-3-4-22(29-27(33)20-5-6-28-26(17-20)38(2,34)35)18-23(19)21-15-24(31-7-11-36-12-8-31)30-25(16-21)32-9-13-37-14-10-32;1-17-21(15-20(16-31-17)32-25(36)18-2-3-30-22(12-18)26(27,28)29)19-13-23(34-4-8-37-9-5-34)33-24(14-19)35-6-10-38-11-7-35;1-17-21(15-20(16-30-17)31-26(35)18-2-3-29-22(12-18)25(27)28)19-13-23(33-4-8-36-9-5-33)32-24(14-19)34-6-10-37-11-7-34/h4-5,14-19H,6-13H2,1-3H3,(H,31,35);2-4,13-17,26H,5-12H2,1H3,(H,31,35);3-6,15-18H,7-14H2,1-2H3,(H,29,33);2-3,12-16H,4-11H2,1H3,(H,32,36);2-3,12-16,25H,4-11H2,1H3,(H,31,35)
• InChIKey: IJDLLITVBNQFMI-UHFFFAOYSA-N
• XLogP: 18.49
• TPSA: 471.91 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 40
• Rotatable Bonds: 29
• Heavy Atoms: 187
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2588.90
LogP ≤ 5	18.49
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The IUPAC name of 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 158714524) is 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide.

What is the SMILES notation for 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The canonical SMILES for 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide is Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(C)C)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.Cc1ncc(NC(=O)c2ccnc(C(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1.

What is the InChIKey of 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

The InChIKey is IJDLLITVBNQFMI-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H34N6O3.C27H29F2N5O3.C27H31N5O5S.C26H27F3N6O3.C26H28F2N6O3/c1-19(2)25-14-21(4-5-29-25)28(35)31-23-17-24(20(3)30-18-23)22-15-26(33-6-10-36-11-7-33)32-27(16-22)34-8-12-37-13-9-34;1-18-23(16-22(17-30-18)31-27(35)20-4-2-3-19(13-20)26(28)29)21-14-24(33-5-9-36-10-6-33)32-25(15-21)34-7-11-37-12-8-34;1-19-3-4-22(29-27(33)20-5-6-28-26(17-20)38(2,34)35)18-23(19)21-15-24(31-7-11-36-12-8-31)30-25(16-21)32-9-13-37-14-10-32;1-17-21(15-20(16-31-17)32-25(36)18-2-3-30-22(12-18)26(27,28)29)19-13-23(34-4-8-37-9-5-34)33-24(14-19)35-6-10-38-11-7-35;1-17-21(15-20(16-30-17)31-26(35)18-2-3-29-22(12-18)25(27)28)19-13-23(33-4-8-36-9-5-33)32-24(14-19)34-6-10-37-11-7-34/h4-5,14-19H,6-13H2,1-3H3,(H,31,35);2-4,13-17,26H,5-12H2,1H3,(H,31,35);3-6,15-18H,7-14H2,1-2H3,(H,29,33);2-3,12-16H,4-11H2,1H3,(H,32,36);2-3,12-16,25H,4-11H2,1H3,(H,31,35).

What are the key properties of 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide?

3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 2588.90 g/mol, XLogP of 18.49, 29 rotatable bonds, 5 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for 3-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-(2,6-dimorpholin-4-yl-4-pyridinyl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(2,6-dimorpholin-4-yl-4-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 158714524), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).