N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide

C132H129F6N39O9 — CID 161076767

About N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide

N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide (PubChem CID 161076767) has the molecular formula C132H129F6N39O9 and a molecular weight of 2519.74 g/mol. Its IUPAC name is N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide.

Molecular Properties

• Compound Name: N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide
• PubChem CID: 161076767
• Molecular Formula: C132H129F6N39O9
• Molecular Weight: 2519.74 g/mol
• Exact Mass: 2518.07
• IUPAC Name: N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide
• SMILES: CCn1cc(C(=O)Nc2cnc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)c(C)n1.COCCNc1ncc(-c2cc(NC(=O)c3cc(C(F)(F)F)ccn3)ccc2C)cc1C#N.COCCNc1ncc(-c2cc(NC(=O)c3cc(C(F)(F)F)ccn3)cnc2C)cc1C#N.Cc1cc(C(=O)Nc2cnc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)n(C)n1.Cc1ncc(NC(=O)c2cc(C(C)(C)C#N)ccn2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1nn(C)cc1C(=O)Nc1cnc(C)c(-c2cnc(N(C)C)c(C#N)c2)c1
• InChI: InChI=1S/C26H25N7O2.C23H20F3N5O2.C22H19F3N6O2.C21H23N7O.2C20H21N7O/c1-17-22(19-10-18(13-27)24(31-14-19)33-6-8-35-9-7-33)12-21(15-30-17)32-25(34)23-11-20(4-5-29-23)26(2,3)16-28;1-14-3-4-18(31-22(32)20-10-17(5-6-28-20)23(24,25)26)11-19(14)16-9-15(12-27)21(30-13-16)29-7-8-33-2;1-13-18(15-7-14(10-26)20(30-11-15)28-5-6-33-2)9-17(12-29-13)31-21(32)19-8-16(3-4-27-19)22(23,24)25;1-6-28-12-19(14(3)26-28)21(29)25-17-8-18(13(2)23-11-17)16-7-15(9-22)20(24-10-16)27(4)5;1-12-17(15-6-14(8-21)19(23-9-15)26(3)4)7-16(10-22-12)24-20(28)18-11-27(5)25-13(18)2;1-12-6-18(27(5)25-12)20(28)24-16-8-17(13(2)22-11-16)15-7-14(9-21)19(23-10-15)26(3)4/h4-5,10-12,14-15H,6-9H2,1-3H3,(H,32,34);3-6,9-11,13H,7-8H2,1-2H3,(H,29,30)(H,31,32);3-4,7-9,11-12H,5-6H2,1-2H3,(H,28,30)(H,31,32);7-8,10-12H,6H2,1-5H3,(H,25,29);6-7,9-11H,1-5H3,(H,24,28);6-8,10-11H,1-5H3,(H,24,28)
• InChIKey: UFJNVGROULQIKB-UHFFFAOYSA-N
• XLogP: 20.84
• TPSA: 639.76 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 42
• Rotatable Bonds: 32
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2519.74
LogP ≤ 5	20.84
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide?

The IUPAC name of N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide (CID 161076767) is N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide.

What is the SMILES notation for N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide?

The canonical SMILES for N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide is CCn1cc(C(=O)Nc2cnc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)c(C)n1.COCCNc1ncc(-c2cc(NC(=O)c3cc(C(F)(F)F)ccn3)ccc2C)cc1C#N.COCCNc1ncc(-c2cc(NC(=O)c3cc(C(F)(F)F)ccn3)cnc2C)cc1C#N.Cc1cc(C(=O)Nc2cnc(C)c(-c3cnc(N(C)C)c(C#N)c3)c2)n(C)n1.Cc1ncc(NC(=O)c2cc(C(C)(C)C#N)ccn2)cc1-c1cnc(N2CCOCC2)c(C#N)c1.Cc1nn(C)cc1C(=O)Nc1cnc(C)c(-c2cnc(N(C)C)c(C#N)c2)c1.

What is the InChIKey of N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide?

The InChIKey is UFJNVGROULQIKB-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H25N7O2.C23H20F3N5O2.C22H19F3N6O2.C21H23N7O.2C20H21N7O/c1-17-22(19-10-18(13-27)24(31-14-19)33-6-8-35-9-7-33)12-21(15-30-17)32-25(34)23-11-20(4-5-29-23)26(2,3)16-28;1-14-3-4-18(31-22(32)20-10-17(5-6-28-20)23(24,25)26)11-19(14)16-9-15(12-27)21(30-13-16)29-7-8-33-2;1-13-18(15-7-14(10-26)20(30-11-15)28-5-6-33-2)9-17(12-29-13)31-21(32)19-8-16(3-4-27-19)22(23,24)25;1-6-28-12-19(14(3)26-28)21(29)25-17-8-18(13(2)23-11-17)16-7-15(9-22)20(24-10-16)27(4)5;1-12-17(15-6-14(8-21)19(23-9-15)26(3)4)7-16(10-22-12)24-20(28)18-11-27(5)25-13(18)2;1-12-6-18(27(5)25-12)20(28)24-16-8-17(13(2)22-11-16)15-7-14(9-21)19(23-10-15)26(3)4/h4-5,10-12,14-15H,6-9H2,1-3H3,(H,32,34);3-6,9-11,13H,7-8H2,1-2H3,(H,29,30)(H,31,32);3-4,7-9,11-12H,5-6H2,1-2H3,(H,28,30)(H,31,32);7-8,10-12H,6H2,1-5H3,(H,25,29);6-7,9-11H,1-5H3,(H,24,28);6-8,10-11H,1-5H3,(H,24,28).

What are the key properties of N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide?

N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide has a molecular weight of 2519.74 g/mol, XLogP of 20.84, 32 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1,3-dimethylpyrazole-4-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-2,5-dimethylpyrazole-3-carboxamide;N-[5-[5-cyano-6-(dimethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-1-ethyl-3-methylpyrazole-4-carboxamide;N-[3-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-[5-cyano-6-(2-methoxyethylamino)-3-pyridinyl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[5-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-4-(2-cyanopropan-2-yl)pyridine-2-carboxamide is sourced from PubChem (CID 161076767), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).