azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

C125H122Cl6F2N26O9S7 — CID 159988152

About azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 159988152) has the molecular formula C125H122Cl6F2N26O9S7 and a molecular weight of 2607.71 g/mol. Its IUPAC name is azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 159988152
• Molecular Formula: C125H122Cl6F2N26O9S7
• Molecular Weight: 2607.71 g/mol
• Exact Mass: 2602.60
• IUPAC Name: azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• SMILES: COc1ccc(CNC(=O)c2sc3nc(C)c(Cl)c(C)c3c2-c2cnn(C)c2)cc1C.Cc1nc2sc(C(=O)N3CCC3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3C4CC3C4)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NCc3ccc(S(=O)(=O)C(C)(F)F)cc3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NCc3cnn(-c4ccccc4)c3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)N[C@H](C)C3CC3)c(-c3cnn(C)c3)c2c(C)c1Cl
• InChI: InChI=1S/C24H21ClN6OS.C23H21ClF2N4O3S2.C23H23ClN4O2S.C19H19ClN4OS.C19H21ClN4OS.C17H17ClN4OS/c1-14-19-20(17-11-27-30(3)13-17)22(33-24(19)29-15(2)21(14)25)23(32)26-9-16-10-28-31(12-16)18-7-5-4-6-8-18;1-12-17-18(15-10-28-30(4)11-15)20(34-22(17)29-13(2)19(12)24)21(31)27-9-14-5-7-16(8-6-14)35(32,33)23(3,25)26;1-12-8-15(6-7-17(12)30-5)9-25-22(29)21-19(16-10-26-28(4)11-16)18-13(2)20(24)14(3)27-23(18)31-21;1-8-13-14(12-6-21-24(3)7-12)17(26-19(13)22-9(2)15(8)20)18(25)23-16-10-4-11(16)5-10;1-9-14-15(13-7-21-24(4)8-13)17(18(25)22-10(2)12-5-6-12)26-19(14)23-11(3)16(9)20;1-9-12-13(11-7-19-21(3)8-11)15(17(23)22-5-4-6-22)24-16(12)20-10(2)14(9)18/h4-8,10-13H,9H2,1-3H3,(H,26,32);5-8,10-11H,9H2,1-4H3,(H,27,31);6-8,10-11H,9H2,1-5H3,(H,25,29);6-7,10-11,16H,4-5H2,1-3H3,(H,23,25);7-8,10,12H,5-6H2,1-4H3,(H,22,25);7-8H,4-6H2,1-3H3/t;;;;10-;/m....1./s1
• InChIKey: OGPGLZQQVYJMNN-NNEKGOKVSA-N
• XLogP: 27.99
• TPSA: 411.26 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 35
• Rotatable Bonds: 25
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2607.71
LogP ≤ 5	27.99
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CID 159988152) is azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is COc1ccc(CNC(=O)c2sc3nc(C)c(Cl)c(C)c3c2-c2cnn(C)c2)cc1C.Cc1nc2sc(C(=O)N3CCC3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NC3C4CC3C4)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NCc3ccc(S(=O)(=O)C(C)(F)F)cc3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)NCc3cnn(-c4ccccc4)c3)c(-c3cnn(C)c3)c2c(C)c1Cl.Cc1nc2sc(C(=O)N[C@H](C)C3CC3)c(-c3cnn(C)c3)c2c(C)c1Cl.

What is the InChIKey of azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is OGPGLZQQVYJMNN-NNEKGOKVSA-N. The full InChI is InChI=1S/C24H21ClN6OS.C23H21ClF2N4O3S2.C23H23ClN4O2S.C19H19ClN4OS.C19H21ClN4OS.C17H17ClN4OS/c1-14-19-20(17-11-27-30(3)13-17)22(33-24(19)29-15(2)21(14)25)23(32)26-9-16-10-28-31(12-16)18-7-5-4-6-8-18;1-12-17-18(15-10-28-30(4)11-15)20(34-22(17)29-13(2)19(12)24)21(31)27-9-14-5-7-16(8-6-14)35(32,33)23(3,25)26;1-12-8-15(6-7-17(12)30-5)9-25-22(29)21-19(16-10-26-28(4)11-16)18-13(2)20(24)14(3)27-23(18)31-21;1-8-13-14(12-6-21-24(3)7-12)17(26-19(13)22-9(2)15(8)20)18(25)23-16-10-4-11(16)5-10;1-9-14-15(13-7-21-24(4)8-13)17(18(25)22-10(2)12-5-6-12)26-19(14)23-11(3)16(9)20;1-9-12-13(11-7-19-21(3)8-11)15(17(23)22-5-4-6-22)24-16(12)20-10(2)14(9)18/h4-8,10-13H,9H2,1-3H3,(H,26,32);5-8,10-11H,9H2,1-4H3,(H,27,31);6-8,10-11H,9H2,1-5H3,(H,25,29);6-7,10-11,16H,4-5H2,1-3H3,(H,23,25);7-8,10,12H,5-6H2,1-4H3,(H,22,25);7-8H,4-6H2,1-3H3/t;;;;10-;/m....1./s1.

What are the key properties of azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2607.71 g/mol, XLogP of 27.99, 25 rotatable bonds, 5 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for azetidin-1-yl-[5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridin-2-yl]methanone;N-(2-bicyclo[1.1.1]pentanyl)-5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(1R)-1-cyclopropylethyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[[4-(1,1-difluoroethylsulfonyl)phenyl]methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;5-chloro-4,6-dimethyl-3-(1-methylpyrazol-4-yl)-N-[(1-phenylpyrazol-4-yl)methyl]thieno[2,3-b]pyridine-2-carboxamide;5-chloro-N-[(4-methoxy-3-methylphenyl)methyl]-4,6-dimethyl-3-(1-methylpyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 159988152), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).